Toxicology - Answers Study of the adverse effects of drugs and poisons on the body
Forensic toxicology - Answers application of scientific methods that are used in toxicology for
the investigation of crime and death
Drug - Answers Any chemical substance, other than one that is required for normal body
function that when applied or introduced into an organism, has the effect of altering the body
function
Poison - Answers Any substance when applied or introduced into the body causes damage,
disturbance of bodily function or adverse effects
Paracelsius (1493-1541) - Answers Created the foundation of toxicology
Foundation of toxicology - Answers "What is there that is not poison? All things are poison and
nothing without poison. Solely the dose determines that a thing is not poison"
Bernardino Ramazzini (1633-1714) - Answers Wrote the basic tenet for the occupational
toxicologist when he stated, "when a doctor visits a working-class home, he should be content
to sit on a three-legged stool if there isn't a gilded chair, and he should take his time for his
examination and to the questions recommended by Hippocrates, he should add one more -
What is your occupation?"
Arsenic - Answers An "inheritance powder" that is odorless, tasteless and readily available for
killing rats. The symptoms of arsenic poisoning include vomiting, diarrhea, stomach pains and
Guillian Barre Syndrome
Marsh Test - Answers Test developed in 1836 for the detection of arsenic in bodily fluids and
tissues
Reinsch Test - Answers Test developed in 1842 to detect heavy metals, including arsenic
Mathiew Orfila (1787 - 1853) - Answers One of the founders of L'Academie de Medecine and
held chair of legal medecine at the Sorbonne, Paris. He published Traite des Poisons ou
Toxicologie Generale, which divided poisons into six classifications. He also proclaimed that
"Investigations of deaths were too important to be left to dabblers and emphasized that
toxicology must be a separate science and autopsy and chemical analysis must be its
foundation" and "that poisons must be absorbed or enter the blood to manifest their toxic
effects"
6 Classifications of poisons - Answers Corrosive, astringents, acrids, stupefying or narcotics,
carcotico-acrids and septic or putrefacants
First forensic toxicology lab - Answers Created in 1868, named "Insitut de medecine legale du
, Paris"
Dr. Wilfred Derome - Answers Spearheaded the opening of thte first forensic lab in all of North
America, first expert in North America to testify in Court on ethyl alcohol in blood in 1922,
invented the microspherometer in 1926, which can reveal the marks left on the surface of
bullets fired from a firearm for the purpose of identification and allowed the presentation of
scientific evidence in Court for the first time on ballistics
RCMP labs - Answers RCMP scientific laboratory established in 1937 in Regina, opened crime
lab in Ottawa in 1942. RCMP have 3 forensic labs across Canada, which are in Vancouver,
Edmonton and Ottawa
Centre of Forensic Sciences - Answers AG lab was renamed Centre of Forensic Sciences in
1966 to enhance appearance of independence, D.M Lucas was appointed director of CFS in
1967, toxicology section expanded to include breath and alcohol testing
Client Groups - Answers Office of the Chief Coroner
Ontario Forensic Pathology Services
Police services from across province
Ontario Fire Marshall's Office
Ministry of the Attorney General
Criminal Lawyers Association
Special Investigations Unit
Transportation Safety Board and Alcohol and Gaming Commission of Ontario
Types of cases - Answers Coroner's death investigations and criminal investigations
Duties of a forensic toxicologist - Answers Perform/direct analysis of body fluids and tissues
Interpretation of analytical findings,
Write reports
Prepare letters of opinions
Provide expert testimony
Training and education
Conduct research and method development
Court testimony - Answers Provide objective and impartial opinion evidence that is within your