Questions & Study Guide | Latest Update 2026
| Graded A+
Epithelialization, the first component of the proliferative phase of
wound healing, is delayed in open wounds until after _______________ has formed.
a. granulation tissue
b. fibrinous meshwork
c. capillary circulation
d. collagenous layers - correct answerA
A mutation has occurred during mitosis of an individual's bone marrow cell. This event
may be the result of the failure of which of the following?
a. progenitor cells
b. fibroblasts
c. stem cells
d. cyclins - correct answerD
A patient has experienced a myocardial infarction with accompanying necrosis of
cardiac muscle, a permanent tissue, What are the ramifications of the fact that cardiac
muscle is a permanent tissue?
a. cardiac muscle cells will remain perpetually in the GI stage of mitosis
b. regeneration of the patients cardiac muscle will be exceptionally low
c. the necrotic cells will be replaced with muscle cells that have limited metabolism
d. the cells will not proliferate - correct answerD
A couple have chosen to pay for the harvesting and storage of umbilical cord blood after
the delivery of their child to secure a future source of embryonic stem cells. What is the
most likely rationale for the couples decision?
a. the stem cells may be able to produce a wide range of body cells
b. the embryonic stem cells allow stable and permanent tissues to enter mitosis
c. the stem cells can change the proliferative capacity of other cells
d. the embryonic stem cells remove cyclin-dependent kinase inhibitors from the body -
correct answerA
The basement membrane surrounding a patients foot wound remains intact, a fact that
bodes well for the wound-healing process. Which of the following components
constitutes this form of the extracellular matrix? Select all that apply
a. prostaglandins
b. fibrous structural proteins
c. lymphocytes
d. water-hydrated gels
, e. glycoproteins - correct answerB, D E
A nursing student is cleaning and changing the dressing on a patients sacral ulcer. The
student has vigorously cleansed the wound bed to remove all traces of the beefy, red
tissue that existed in the wound bed. The student has most likely removed:
a. necrotic tissue
b. granulation tissue
c. stem cells
d. the extracellular matrix - correct answerB
a 12 yr old boys severe wound that he received from a dog bite has begun to heal &
currently shows no signs of infection. Which of the following processes occurred first
during this process of repair by connective tissue deposition?
a. reorganization of fibrous tissue
b. angiogenesis
c. emigration of fibroblasts to the wound site
d. deposition of the extracellular matrix - correct answerB
Which of the following wounds is most likely to heal by secondary intention?
a. a finger laceration that a cook received while cutting up onions
b. a boys road rash that he got by falling off his bike
c. a needlestick injury that a nurse received when injecting a patient's medication
d. the incision from a teenagers open appendectomy - correct answerB
a patient underwent an open cholecystectomy 4 days ago & her incision is now in the
proliferative phase of healing. What is the dominant cellular process that characterizes
this phase of the patients healing?
a. hemostasis and vasoconstriction
b. keloid formation
c. collagen secretion by fibroblasts
d. phagocytosis by neutrophils - correct answerC
Which of the following surgical patients is most likely to experience enhanced wound
healing as a result of his or her diet?
a. a patient who eats a high-calorie diet & large amounts of red meat
b. a patient who is a vegetarian who eats organic foods whenever possible
c. a patient who practices carefully calorie control & who avoids animal fats
d. a patient who is receiving TPN d/t recurrent nausea - correct answerA
Which of the following patients is most likely to experience impaired wound healing?
a. a patient with a diagnosis of type 1 DM & a hx of poor blood sugar control
b. a child whose severe cleft lip and palate have required a series of surgeries over
several months
c. a patient who takes nebulized bronchodilators several times daily to treat COPD
d. a patient w/ persistent HTN who takes a b-adrenergic blocker & a K+ wasting diuretic
daily - correct answerA