, THE IMMUNE SYSTEM, FOURTH EDITION CHAP
79 79 79 79 79
TER 1: ELEMENTS OF THE IMMUNE SYSTEM
79 79 79 79 79 79
AND THEIR ROLES IN DEFENSE
79 79 79 79
©79201579GARLAND79 SCIENCE
1–1 The79last79cases79of79smallpox79were79reported79in79the79 .
a. 1950s
b. 1960s
c. 1970s
d. 1980s
e. 1990s.
1–2 The79first79line79of79defense79against79microorganisms79that79infect79the79body79is79referred79to79as
.
a. opportunistic79immunity
b. innate79immunity
c. adaptive79immunity
d. primary79immunity
e. central79immunity.
1–3 Which79of79the79following79pairs79is79mismatched?
a. innate79immunity:79highly79specialized79defenses
b. secondary79immune79response:79immunological79memory
c. hematopoiesis:79bone79marrow
d. phagocytosis:79uptake79and79killing79of79microbes
e. lymphocyte79recirculation:79continuous79transport79between79blood79and79lymph.
1–4 All79of79the79following79are79examples79of79chemical79barriers79of79innate79immunity79except79 .
a. lactic79acid
b. normal79microbiota
c. lysozyme
d. fatty79acids
e. proteases.
1–5 When79effector79lymphocytes79secrete79 ,79an79inflammatory79response79ensues.
a. lysozyme
b. defensins
c. lymph
d. sebum
e. cytokines.
1–6
The79thin79layer79of79cells79that79makes79up79the79interior79lining79of79the79blood79vessels79is79called79t
he
.
1
,a. mucosa
2
, b. epithelium
c. endothelium
d. connective79tissue
e. lymphoid79tissue.
1–7 Identify79the79incorrect79statement79regarding79hematopoiesis.
a. Hematopoiesis79is79a79continuous79process79that79occurs79throughout79one‘s79lifetime.
b. The79location79for79hematopoiesis79differs79with79age.
c. Self79renewal79is79necessary79to79replenish79the79supply79of79hematopoietic79stem79cells.
d. Most79hematopoiesis79occurs79in79the79bone79marrow79after79birth.
e. Leukocytes,79but79not79erythrocytes,79must79go79through79hematopoiesis79in79order79to79develop.
1–8 The79progenitors79of79macrophages79are79 .
a. megakaryocytes
b. dendritic79cells
c. monocytes
d. neutrophils
e. erythrocytes
f. M79cells.
1–9 act79as79cellular79messengers79by79delivering79degraded79pathogens79to79lymphoid79organs.
a. Plasma79cells
b. Dendritic79cells
c. Large79granular79lymphocytes
d. Mast79cells
e. Basophils.
1–10 Another79name79for79a79large79granular79lymphocyte79is79a79 .
a. plasma79cell
b. helper79T79cell
c. monocyte
d. natural79killer79cell
e. eosinophil.
1–11 Effector79cells79that79secrete79antibodies79are79known79as79 .
a. natural79killer79cells
b. cytotoxic79T79cells
c. helper79T79cells
d. M79cells
e. plasma79cells
f. regulatory79T79cells.
1–12
Spherical79regions79in79lymph79nodes79containing79areas79that79are79packed79dens
ely79with79proliferating79B79cells79are79called79 .
a. efferent79vessels
b. germinal79centers
3
79 79 79 79 79
TER 1: ELEMENTS OF THE IMMUNE SYSTEM
79 79 79 79 79 79
AND THEIR ROLES IN DEFENSE
79 79 79 79
©79201579GARLAND79 SCIENCE
1–1 The79last79cases79of79smallpox79were79reported79in79the79 .
a. 1950s
b. 1960s
c. 1970s
d. 1980s
e. 1990s.
1–2 The79first79line79of79defense79against79microorganisms79that79infect79the79body79is79referred79to79as
.
a. opportunistic79immunity
b. innate79immunity
c. adaptive79immunity
d. primary79immunity
e. central79immunity.
1–3 Which79of79the79following79pairs79is79mismatched?
a. innate79immunity:79highly79specialized79defenses
b. secondary79immune79response:79immunological79memory
c. hematopoiesis:79bone79marrow
d. phagocytosis:79uptake79and79killing79of79microbes
e. lymphocyte79recirculation:79continuous79transport79between79blood79and79lymph.
1–4 All79of79the79following79are79examples79of79chemical79barriers79of79innate79immunity79except79 .
a. lactic79acid
b. normal79microbiota
c. lysozyme
d. fatty79acids
e. proteases.
1–5 When79effector79lymphocytes79secrete79 ,79an79inflammatory79response79ensues.
a. lysozyme
b. defensins
c. lymph
d. sebum
e. cytokines.
1–6
The79thin79layer79of79cells79that79makes79up79the79interior79lining79of79the79blood79vessels79is79called79t
he
.
1
,a. mucosa
2
, b. epithelium
c. endothelium
d. connective79tissue
e. lymphoid79tissue.
1–7 Identify79the79incorrect79statement79regarding79hematopoiesis.
a. Hematopoiesis79is79a79continuous79process79that79occurs79throughout79one‘s79lifetime.
b. The79location79for79hematopoiesis79differs79with79age.
c. Self79renewal79is79necessary79to79replenish79the79supply79of79hematopoietic79stem79cells.
d. Most79hematopoiesis79occurs79in79the79bone79marrow79after79birth.
e. Leukocytes,79but79not79erythrocytes,79must79go79through79hematopoiesis79in79order79to79develop.
1–8 The79progenitors79of79macrophages79are79 .
a. megakaryocytes
b. dendritic79cells
c. monocytes
d. neutrophils
e. erythrocytes
f. M79cells.
1–9 act79as79cellular79messengers79by79delivering79degraded79pathogens79to79lymphoid79organs.
a. Plasma79cells
b. Dendritic79cells
c. Large79granular79lymphocytes
d. Mast79cells
e. Basophils.
1–10 Another79name79for79a79large79granular79lymphocyte79is79a79 .
a. plasma79cell
b. helper79T79cell
c. monocyte
d. natural79killer79cell
e. eosinophil.
1–11 Effector79cells79that79secrete79antibodies79are79known79as79 .
a. natural79killer79cells
b. cytotoxic79T79cells
c. helper79T79cells
d. M79cells
e. plasma79cells
f. regulatory79T79cells.
1–12
Spherical79regions79in79lymph79nodes79containing79areas79that79are79packed79dens
ely79with79proliferating79B79cells79are79called79 .
a. efferent79vessels
b. germinal79centers
3
