PN1005 Pharmacology Midterm |\ |\ |\
questions with answers |\ |\
Pharmacokinetics - CORRECT ANSWERS ✔✔How the body |\ |\ |\ |\ |\ |\ |\
affects the drug |\ |\
4 stages of pharmacokinetics - CORRECT ANSWERS ✔✔1.
|\ |\ |\ |\ |\ |\ |\ |\
Absorption
2. Distribution
|\
3. Metabolism
|\
4. Excretion
|\
Absorption - CORRECT ANSWERS ✔✔what happens to a
|\ |\ |\ |\ |\ |\ |\ |\
drug from the time it enters the body until it enters the
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\
circulating fluid; intravenous administration causes the
|\ |\ |\ |\ |\ |\
drug to directly enter the circulating blood, bypassing the
|\ |\ |\ |\ |\ |\ |\ |\ |\
many complications of absorption from other routes.
|\ |\ |\ |\ |\ |\
Distribution - CORRECT ANSWERS ✔✔The movement of |\ |\ |\ |\ |\ |\ |\
drug to and from the bloodstream and various tissues of
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\
the body |\
, Pharmacodynamics - CORRECT ANSWERS ✔✔How the |\ |\ |\ |\ |\ |\
drug affects the body |\ |\ |\
Controlled Drugs and Substances Act - CORRECT |\ |\ |\ |\ |\ |\ |\
ANSWERS ✔✔Class 1: heroin |\ |\ |\
Class 2: hydromorphone |\ |\ |\
Class 3: Codeine |\ |\
Biotransformation (metabolism) - CORRECT ANSWERS |\ |\ |\ |\ |\
✔✔the process by which drugs are changed into new, less
|\ |\ |\ |\ |\ |\ |\ |\ |\
active chemicals
|\ |\
first pass effect - CORRECT ANSWERS ✔✔a phenomenon
|\ |\ |\ |\ |\ |\ |\ |\
in which drugs given orally are carried directly to the liver
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\
after absorption, where they may be largely inactivated
|\ |\ |\ |\ |\ |\ |\ |\ |\
by liver enzymes before they can enter the general
|\ |\ |\ |\ |\ |\ |\ |\ |\
circulation; oral drugs frequently are given in higher |\ |\ |\ |\ |\ |\ |\ |\
doses than drugs given by other routes because of this
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\
early breakdown |\
Protein bound drugs - CORRECT ANSWERS ✔✔Affects the
|\ |\ |\ |\ |\ |\ |\ |\
distribution of a drug; when the drug is bound to protein, |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\
it is unable to pass through capillary walls; may cause
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\
drug toxicity. when the patient has a lower-than-expected
|\ |\ |\ |\ |\ |\ |\ |\
protein level, the distribution of the drug is altered.
|\ |\ |\ |\ |\ |\ |\ |\
questions with answers |\ |\
Pharmacokinetics - CORRECT ANSWERS ✔✔How the body |\ |\ |\ |\ |\ |\ |\
affects the drug |\ |\
4 stages of pharmacokinetics - CORRECT ANSWERS ✔✔1.
|\ |\ |\ |\ |\ |\ |\ |\
Absorption
2. Distribution
|\
3. Metabolism
|\
4. Excretion
|\
Absorption - CORRECT ANSWERS ✔✔what happens to a
|\ |\ |\ |\ |\ |\ |\ |\
drug from the time it enters the body until it enters the
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\
circulating fluid; intravenous administration causes the
|\ |\ |\ |\ |\ |\
drug to directly enter the circulating blood, bypassing the
|\ |\ |\ |\ |\ |\ |\ |\ |\
many complications of absorption from other routes.
|\ |\ |\ |\ |\ |\
Distribution - CORRECT ANSWERS ✔✔The movement of |\ |\ |\ |\ |\ |\ |\
drug to and from the bloodstream and various tissues of
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\
the body |\
, Pharmacodynamics - CORRECT ANSWERS ✔✔How the |\ |\ |\ |\ |\ |\
drug affects the body |\ |\ |\
Controlled Drugs and Substances Act - CORRECT |\ |\ |\ |\ |\ |\ |\
ANSWERS ✔✔Class 1: heroin |\ |\ |\
Class 2: hydromorphone |\ |\ |\
Class 3: Codeine |\ |\
Biotransformation (metabolism) - CORRECT ANSWERS |\ |\ |\ |\ |\
✔✔the process by which drugs are changed into new, less
|\ |\ |\ |\ |\ |\ |\ |\ |\
active chemicals
|\ |\
first pass effect - CORRECT ANSWERS ✔✔a phenomenon
|\ |\ |\ |\ |\ |\ |\ |\
in which drugs given orally are carried directly to the liver
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\
after absorption, where they may be largely inactivated
|\ |\ |\ |\ |\ |\ |\ |\ |\
by liver enzymes before they can enter the general
|\ |\ |\ |\ |\ |\ |\ |\ |\
circulation; oral drugs frequently are given in higher |\ |\ |\ |\ |\ |\ |\ |\
doses than drugs given by other routes because of this
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\
early breakdown |\
Protein bound drugs - CORRECT ANSWERS ✔✔Affects the
|\ |\ |\ |\ |\ |\ |\ |\
distribution of a drug; when the drug is bound to protein, |\ |\ |\ |\ |\ |\ |\ |\ |\ |\ |\
it is unable to pass through capillary walls; may cause
|\ |\ |\ |\ |\ |\ |\ |\ |\ |\
drug toxicity. when the patient has a lower-than-expected
|\ |\ |\ |\ |\ |\ |\ |\
protein level, the distribution of the drug is altered.
|\ |\ |\ |\ |\ |\ |\ |\
