NSC 830 Advanced Pharmacology Questions
and Answers (100% Correct Answers) Already
Graded A+
Narrow Specturm [ Ans: ] Treat limited # of organisms,
Less likely to disrupt normal flora, organism identified.
Broad Specturm [ Ans: ] Treats multiple organisms, more
likely to disrupt normal flora, causative agent unknown.
Why would you select abx? [ Ans: ] Is antimicrobial
therapy indicated, make a clinical diagnosis, collection of
specimens for a cx or lab test, make microbial diagnosis,
select drug.
Extended spectrum [ Ans: ] treats multiple organisms,
more likely to disrupt normal flora, used when causative
organism is unknown.
Gram positive [ Ans: ] Purple, thick layer
Example of gram positive [ Ans: ] Group A beta-strep
Strep PNA
Gram negative [ Ans: ] Red or pink, thin layer
Example of gram negative [ Ans: ] H. influenza
N. Gonoccocus
,Atypical Organism [ Ans: ] colorless, no layer
Example of Atypical organism [ Ans: ] Macrolides-
erythromycins
True or False: Atypical bacteria are resistent to becta-
lactum abx [ Ans: ] True
Risk factors for Drug Resistant Strep PNA (DRSP) [ Ans: ]
Recent abx use
Older >65
Multiple Comorbidtities ( COPD, DM, HF, renal failure)
Daycare worker
Alcoholism
Immunosuppressed (including chronic steroid use >10
mg/day long term).
Treatment for Drug Resistant Strep PNA [ Ans: ] High dose
amoxicillin 3-4g/day
Respiratory fluoroquinolones: moxifloxican, gemifloxican,
levofloxacin.
Tehlithromycin: use limited due to hepatoxicity
, Factors to determine when selecting an abx... [ Ans: ]
Allergy history (PCN- risk of cross allergy with
cephalosporins)
Age- (Renal function- neonates and elderly)
Pregnancy
Immunocompromised status
Affordability
Taste and convenience
What are 2 abx contraindicated in pregnancy? [ Ans: ]
tetracyclines
fluoroquinolone
Do immunocompromised patients get bactericidal or
baceriostiatic? [ Ans: ] Bactericidals
What are bactericidals? [ Ans: ] Kills bacteria
What are bacteriostatic? [ Ans: ] Restrains production of
bacteria. The patient needs a good immune system.
Minimum inhibitory concentration (MIC) [ Ans: ] Min.
amount of abx used to inhibit growth of bacteria. Abx
usually dosed 2-4 times MIC
Teaching the patient to ..... [ Ans: ] Take ALL of medication
and Answers (100% Correct Answers) Already
Graded A+
Narrow Specturm [ Ans: ] Treat limited # of organisms,
Less likely to disrupt normal flora, organism identified.
Broad Specturm [ Ans: ] Treats multiple organisms, more
likely to disrupt normal flora, causative agent unknown.
Why would you select abx? [ Ans: ] Is antimicrobial
therapy indicated, make a clinical diagnosis, collection of
specimens for a cx or lab test, make microbial diagnosis,
select drug.
Extended spectrum [ Ans: ] treats multiple organisms,
more likely to disrupt normal flora, used when causative
organism is unknown.
Gram positive [ Ans: ] Purple, thick layer
Example of gram positive [ Ans: ] Group A beta-strep
Strep PNA
Gram negative [ Ans: ] Red or pink, thin layer
Example of gram negative [ Ans: ] H. influenza
N. Gonoccocus
,Atypical Organism [ Ans: ] colorless, no layer
Example of Atypical organism [ Ans: ] Macrolides-
erythromycins
True or False: Atypical bacteria are resistent to becta-
lactum abx [ Ans: ] True
Risk factors for Drug Resistant Strep PNA (DRSP) [ Ans: ]
Recent abx use
Older >65
Multiple Comorbidtities ( COPD, DM, HF, renal failure)
Daycare worker
Alcoholism
Immunosuppressed (including chronic steroid use >10
mg/day long term).
Treatment for Drug Resistant Strep PNA [ Ans: ] High dose
amoxicillin 3-4g/day
Respiratory fluoroquinolones: moxifloxican, gemifloxican,
levofloxacin.
Tehlithromycin: use limited due to hepatoxicity
, Factors to determine when selecting an abx... [ Ans: ]
Allergy history (PCN- risk of cross allergy with
cephalosporins)
Age- (Renal function- neonates and elderly)
Pregnancy
Immunocompromised status
Affordability
Taste and convenience
What are 2 abx contraindicated in pregnancy? [ Ans: ]
tetracyclines
fluoroquinolone
Do immunocompromised patients get bactericidal or
baceriostiatic? [ Ans: ] Bactericidals
What are bactericidals? [ Ans: ] Kills bacteria
What are bacteriostatic? [ Ans: ] Restrains production of
bacteria. The patient needs a good immune system.
Minimum inhibitory concentration (MIC) [ Ans: ] Min.
amount of abx used to inhibit growth of bacteria. Abx
usually dosed 2-4 times MIC
Teaching the patient to ..... [ Ans: ] Take ALL of medication
