Tcr hla Guías de estudio, Notas de estudios & Resúmenes

Antigen Shape to Antibody Shape - Answer-Simple = Pocket Large = Groove Complex = Extended Surface Type of chemical bond used with antibodies - Answer-1)Electrostatic 2) Hydrogen bonds 3) Van der Waals forces 4) Hydrophobic interactions Cross reactivity - Answer-The biding site can accept a shape close enough in shape and get reaction or a stable structure Ex. Penicillin and other B-lactam Diagnostic tests for antibody/antigen - Answer-ELISA Lateral Flow test (pregnancy hCG) Immunofl...

ISBB REVIEW QUESTIONSY. entercolitica Most common contaminant in blood bags Rubeola 2 weeks Rubella 4 weeks platelet concentrate 5.5 x 10 to the 11th power (whole blood) platelet concentrate 3.0 x 10 to the 11th power (apheresis) Cryoprecipitate Heavy spin 56C for 30 min. Inactivation of serum 56C for 10 min Reinactivation of serum 10 minutes How many minutes does HBV inactivates using 1:100 dilution S. epidermidis B. cereu...

Immunology Exam 2 - Questions and Answers NKG2D is an activating receptor expressed on NK cells, : T cells, and some cytotoxic : T cells. When stressed or infected cells up-regulate receptors that bind to and activate NKG2D molecules, the stressed or infected cells will be killed. This pathway relies on the fact that stressed or infected cells up-regulate: A. All classical MHC class I molecules B. HLA-C molecules that bind KIRs C. MHC class Ib genes such as MICA, MICB, and RAET1 D. Qa-1 and HLA...

Innate immune response -Nonspecific immune response Macrophages Killer (NK) cell Complement Antibodies Enzymes/chemicals adaptive immune response -specific immune response • Antigen dependent • Produced only on an as-needed basis • Two types 1. Cellular • T cells • NK cells • Antigen presenting cells (APCs) 2. Humoral • Antibodies made by B cells state source and function of IL1 -Produced by many cells -T & neutrophil activation, pyrogenic sta...

CHT Practice Exam Questions And Answers With Verified Solutions Bacterial Lysing Correct Answer: Not a role of antibodies in host defense Primary role of proteasome in Ag presentation Correct Answer: Processing cytoplasmic proteins Peptides that bind to MHC class I and II are different EXCEPT Correct Answer: They anchor in the middle instead of the end of the MHC HLA-DM is primarily involved in Correct Answer: Loading Ag onto HLA-DR molecules The Ig that binds the most complement Correct...

MB (ASCP) 2022 - Translocations, Diseases, Pharma, Polymerases, & more Chronic Myeloid Leukemia (CML) t(9;22) BCR-ABL translocation Ewing sarcoma t(11;22) EWS-FLI1 Acute Lymphocytic Leukemia (ALL) t(9;22) BCR-ABL p190 protein Follicular Lymphoma t(14;18) BCL2 translocation Mantle Cell Lymphoma t(11;14) bcl-1 translocation CCND1-IgH Burkitt Lymphoma t(8;14) MYC gene translocation Rhabdomyosarcoma (alveolar); Cancer/solid tumor t(2;13) or t(1;13) PAX3-FKHR and PAX7-FKHR "ARMS" translocatio...

MB (ASCP) 2021 - Translocations, Diseases, Pharma, Polymerases, & more correctly answeredChronic Myeloid Leukemia (CML) t(9;22) BCR-ABL translocation Ewing sarcoma t(11;22) EWS-FLI1 Acute Lymphocytic Leukemia (ALL) t(9;22) BCR-ABL p190 protein Follicular Lymphoma t(14;18) BCL2 translocation Mantle Cell Lymphoma t(11;14) bcl-1 translocation CCND1-IgH Burkitt Lymphoma t(8;14) MYC gene translocation Rhabdomyosarcoma (alveolar); Cancer/solid t...

What is the hapten- carrier effect? Small-molecule antigen requires covalent linkage to a larger carrier to stimulate adaptive immune response. The process is achieved in collaboration between hapten-specific B cells and carrier-specific T cells. This is the basis of developing conjugated vaccines. What are the common superantigens and related diseases? SEB and SEC cause food poisoning; TSST and SPE-C cause toxic shock syndrome. Superantigens bind the Vβ region of TCRs (CDR4) and outside of...

MB (ASCP) 2021 - Translocations, Diseases, Pharma, Polymerases, & more completedChronic Myeloid Leukemia (CML) t(9;22) BCR-ABL translocation Ewing sarcoma t(11;22) EWS-FLI1 01:03 01:08 Acute Lymphocytic Leukemia (ALL) t(9;22) BCR-ABL p190 protein Follicular Lymphoma t(14;18) BCL2 translocation Mantle Cell Lymphoma t(11;14) bcl-1 translocation CCND1-IgH Burkitt Lymphoma t(8;14) MYC gene translocation Rhabdomyosarcoma (alveolar); Cance...

CPPS 307 (Pharmacology: Cancer Immunotherapy)questions and answers 2023Different Modes of Tumor Immunotherapy - correct answer 1. Passive immunotherapy with monoclonal antibodies or antibody-like molecules 2. Adoptive cellular therapy with antitumor T cells 3. Immune checkpoint blockade-targeting T cell inhibitory pathways 4. Vaccination with tumor antigens 5. Various other approaches for stimulating antitumor immunity Passive immunotherapy with Abs or antibody-like molecules - correct an...