MHC gene diversity: mechanisms of creation and maintenance Disease associations of MHC with: - Infectious disease - Autoimmunity

Processing of pathways for MHC II presentation Structure of MHC II Effect of MHCII-peptide presentation

Ontogeny of myeloid cells How function varies in development Subsets of monocytes and macrophages

DC functions and activation

Natural killer cell functions NK receptors regulating activity NK genes

Importance of post-transcriptional regulation in activating and inactivating innate immunity

immune cells at the maternal-fetal interface How tolerance to the fetus is maintained Pre-eclampsia and failure of placentation

Differences in the structure of classical and non-classical MHC, and how this relates to their differing function

Theories of how TCR signalling is triggered, and evidence supporting these

Factors promoting Th17 differentiation, and their mechanism of affecting gene expression Role of Th17 cells in immunity and disease states