Blood Physiology
1
,Blood 4
Structure and function of blood, RBCs and Haemoglobin: 4
Cellular functions: 5
Origin and production of blood cells: 6
Haematopoiesis: 7
Erythropoiesis: 8
Regulation of Erythropoiesis: 9
Haematocrit: 10
Erythrocytes: 11
Haemoglobin Synthesis: 12
Haemoglobin breakdown: 12
Haemoglobin Function: 13
Anaemia: 16
Signs and symptoms: 16
Anaemia mechanisms and measurements: 16
Regenerative vs Non-regenerative: 17
Blood Groups: 20
Anti-blood group antibodies: 21
Transfusions: 21
Rhesus blood group: 22
Haemostasis: 23
Plug formation: 23
Coagulation: 24
Fibrinolysis: 26
Clotting measurement: 27
Anticoagulant pathways and therapeutics: 27
Coagulation disorders: 30
2
,Blood
Structure and function of blood, RBCs and Haemoglobin:
Homeostasis management:
- taking up oxygen and CO2
- taking up nutrients and waste products
- transporting O2 and nutrients to all cells for metabolism ATP (central function)
- releasing CO2 into the lungs
- releasing metabolic wastes into kidneys/ liver
- transporting hormones
3
, Components of blood:
Plasma:
HCO3- (buffer which carries CO2 to lungs)
Nutrients = glucose, lipids, micronutrients
Proteins = albumin, inactive clotting factors and anticoagulants
Hormones
Waste = urea, uric acid and bilirubin
Cells - Haematocrit:
RBCs
WBCs
Platelets
4
1
,Blood 4
Structure and function of blood, RBCs and Haemoglobin: 4
Cellular functions: 5
Origin and production of blood cells: 6
Haematopoiesis: 7
Erythropoiesis: 8
Regulation of Erythropoiesis: 9
Haematocrit: 10
Erythrocytes: 11
Haemoglobin Synthesis: 12
Haemoglobin breakdown: 12
Haemoglobin Function: 13
Anaemia: 16
Signs and symptoms: 16
Anaemia mechanisms and measurements: 16
Regenerative vs Non-regenerative: 17
Blood Groups: 20
Anti-blood group antibodies: 21
Transfusions: 21
Rhesus blood group: 22
Haemostasis: 23
Plug formation: 23
Coagulation: 24
Fibrinolysis: 26
Clotting measurement: 27
Anticoagulant pathways and therapeutics: 27
Coagulation disorders: 30
2
,Blood
Structure and function of blood, RBCs and Haemoglobin:
Homeostasis management:
- taking up oxygen and CO2
- taking up nutrients and waste products
- transporting O2 and nutrients to all cells for metabolism ATP (central function)
- releasing CO2 into the lungs
- releasing metabolic wastes into kidneys/ liver
- transporting hormones
3
, Components of blood:
Plasma:
HCO3- (buffer which carries CO2 to lungs)
Nutrients = glucose, lipids, micronutrients
Proteins = albumin, inactive clotting factors and anticoagulants
Hormones
Waste = urea, uric acid and bilirubin
Cells - Haematocrit:
RBCs
WBCs
Platelets
4
