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Summary

Summary Genetics: DNA - IEB Matric Life Sciences

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These notes include in depth, detailed summaries, with visual diagrams and colour coding of the following topics: - Structure and Function of DNA - DNA replication - Mitochondrial DNA - Structure and function of RNA - Protein Synthesis: Transcription and translation - Genetic aberrations and mutations - DNA Fingerprinting These notes are in the form of digital hand written notes. I used these notes personally when studying for my finals in Life Sciences - I obtained 100% for my portfolio assessments and 95% as my final mark (top 1% nationally).

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Life at molecular, cellular and tissue level

, N det
nucleic acids info thatc ontrols cellular
activity developmentofa n entire
·

store
org
-
+




↳
done
through controlling protein synthesis

proteins make up structure of body
· -




enzymes control chemical processes control structure and functioning
->
=
-




deoxyribom a c h i n
voe cial




volisa na r e


·
19505




King's Rosalind Franklin,Maurice Wilkins
College
· -




↳
Structure:looked X-ray
at
crystallography

Cavendish Institute, Cambridge Watson
·
-
Francis Crick, James


↳>
analyzed x-ray, data collectedby Franklin


↳
built model outo fbrass plate clamps
+
realised:nucleic acids
-




arranged like twisted ladder wl c runners made of


phosphates +




sugars
+




rungs

↳ made ofb ases= of
rungs pairs


organic pairs


Watson+Crick developed ideas about for
geneticreplication:when separate, each template new chain
·



I strands



thattripletcode (DNA) to (RNA)=
Crick Brenner genetic proof used transferred cytoplasm protein synthesis
-
·

+
+




↳functions
replicate
-


itself


carries
genetic sequences
-




Nobel Prize credits


Rosalind Franklin only one we chem. degree
· =




↓
worked discovered helical shape butd idn'twantto announce until she hadsufficientevidence
mostly alone +




↳
died at 37 to cancer before
-




expressing work



Wilkins= for in
Watson, Crick wor Nobel Prize
physiolog/medicine
·

+ 1962


↳
only goes to living recipients:F ranklin notcredited



↳ 8: ethical question ofw omen in STEM
being credited




toc a t i o n



nucleus:important partofchromosomes
·




↳
make up chromatin network


↳
found in
to chromation chromosomal material made of
DNA, RNA+ histone proteins as a
=




non-dividing cell


↳
coiled-so as to fit =2m ofD NA


·

extranuclear DNA - small amounts in mitochondria in plants - animals chloroplasts
+


in plants


&
mitochondria their
supports cell
theory of
being own
orgs originally



~S t r e e tr e



·



long, twisted ladder -
I strands stable,
-




3p double helir


nucleotides:1 . deoxyribose molecule (S)
long polymer made of
m onomers
sugar
= :
·




2. Phosphate molecule (P)


base adenine (A) &All Gets
3.
nitrogenous Tea Cold



thymine (T)
·




·



guanine (G)


cytosine (C)
·

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