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Summary CRISPR notes

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CRISPR ieb syllabus notes

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CRISPR
CLUSTERED REGULARLY INTERSPACED SHORT PALINDROMIC REPEATS

this technique lets scientists edit DNA in plants and animals

Jennifer Doudna and Emmanuelle took home the 2020 Nobel Prize in chemistry for discovering
it
these repeats are found in bacteria's DNA
they are copies of small pieces of viruses
bacteria use these like collections of mug shots to identify bad viruses
Cas9 is an enzyme that can cut apart DNA
bacteria fight off viruses by sending the Cas9 to chop up viruses that have a mug shot in the
collection
this CRISPR/Cas9 tool was first described in 2012 and 2013
Scientists used it to alter the genome of organisms
It can be used to tweak almost any genes and to fix genetic diseases, combat viruses and sterilize mosquitoes
They can use it to prepare pig organs for human transplants and beef up beagles' muscles

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