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Summary of Histology

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Summary of basic histology of the human body

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APES: histology


Tissue
 Groups of specialised cells that are similar in structure and perform similar functions
 The multicellularity can be an advantage because it has a longer lifespan, specialisation and
production & repair of damaged cells by employing other cell types.
 Cell -> tissue -> organ -> organ system
 Epithelial, connective, muscle and nervous tissue.
 Cell junctions hold adjacent cells together
- tight junctions: seal plasma membranes tightly together (digestive tract + bladder lining)
- adhesion junctions: permit some movement between cells, allow tissues to stretch and
bend (skin)
- gap junctions: protein channels enable movement of materials between cells (liver + heart)




Epithelial Tissue

 Polarised: apical (faces external environment or lumen of a tube where it is often involved in
absorption/secretion) and basal (mediates attachment to underlying tissue or surface via
integrins)
 Tightly packed sheets of cells
 Basement membrane: noncellular layer directly beneath epithelial tissue composed of
proteins secreted by epithelial cells & connective tissue. Provides structural support to
overlying cells and attaches epithelial layer to underlying tissues
 Simple (single layer, adapted for diffusion across cell barriers) vs. stratified (multiple layers,
provide protection)

Simple squamous Lines blood vessels and alveoli.
Permits exchange of nutrients, wastes and
gases.

, APES: histology




Simple cuboidal Lines kidney tubules and glands.
Secretes and reabsorbs water and small
molecules.




Simple columnar Lines most digestive organs.
Absorbs nutrients & produces mucous.




Stratified squamous Outer layer of skin, mouth + vagina.
Protects against abrasion, drying out and
infection.




Stratified cuboidal Lines ducts of sweat glands.
Secretes water and ions.




Stratified columnar Lines epididymis, mammary glands + larynx.
Secretes mucous.

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