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DNA : code of life - grade 12

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This includes a summary of the topic DNA code of life. Terminology needed is included as well as process. Differences between DNA and RNA and DNA profiling made easy

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LIFE SCIENCE - DNA CODE OF LIFE (simple and
easy summary)
DNA-CODE OF LIFE




STRUCTURE OF A CELL:

• Plant cells have a cell wall

• Animal cells have no cell wall

• Ribosomes- site of protein synthesis, located in cytoplasm

• Nucleus - nuclear membrane has nuclear pores to allow entry and exit of substances

- Nucleoplasm contains free DNA and RNA nucleotides

- Nucleolus produces ribosomes

- Chromatin network contains DNAwhich forms chromosomes containing the genetic code of a person.



NUCLEIC ACIDS

• Two types: DNA ( deoxyribonucleic acid) and RNA (ribonucleic acid)

• Made up of monomers(smallest building blocks) called nucleotides

• Nucleotide: made up of a phosphate group, a sugar and a nitrogen base



DNA: LOCATION, STRUCTURE AND FUNCTIONS

• Location: present in the nucleus - makes up genes on chromosomes(nuclear DNA)

present in mitochondria(mitochondrial DNA),


present in chloroplasts (chloroplastic DNA) –found in plant

cells only

• Three types – nuclear DNA ,mitochondrial DNA, chloroplastic DNA

• History of Discovery of DNA

- James Watson and Francis Crick formulated the double helix structure of DNA in 1953

, - Maurice Wilkins and Rosalind Franklin also did research on DNA structure

- In 1952 Rosalind took X-ray photos of DNA which was shown to Francis Crick. Using this Watson and
Crick were able to build 3-D models of the structure of DNA

NOTE: Rosalind Franklin and Wilkins produced the first X-ray pictures of DNA

Watson and Crick put forward their model of DNA which shows a double helix with
complementary base pairs.

• Structure:

- Double stranded, strands held together by weak hydrogen bonds

- Natural shape of DNA – double helix

- DNA nucleotide made up of: phosphate group, sugar(deoxyribose) and nitrogenous bases (A,T,G,C)-
adenine, thymine, guanine and cytosine

- Pairing of bases occurs as follows: A-T, G-C

- NOTE: always an equal number of adenine and thymine and equal number of cytosine and guanine
occurs

• Functions:

- DNA makes up genes which carry hereditary information

- DNA contains coded information for protein synthesis



DNA REPLICATION

➢ Occurs to form identical copies of DNA

➢ Process takes place during Interphase of cell division



➢ PROCESS

• Double helix of DNA unwinds

• Weak hydrogen bonds break

• The two strands unzip

• to form two separate strands

• Both DNA strands serve as templates

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