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benign tumor- lipoma
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1 Atrophy 2 urate accumulation
3 -oma 4 Metaplasia
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Terms in this set (93)
, E. Cells decrease in size
P. Still functional
Atrophy
Physiologic: thymus gland in early childhood
Pathological: disuse
E. Increase in cell size
P. Increased workload
Hypertrophy
Physiologic: weightlifting
Pathologic: cardiomegaly from HTN
E. Increase in cell number
P. Increased cellular division
Hyperplasia
Physiologic: liver regeneration
Pathologic: endometrial- usually r/t hormones
E. Cells change in size, shape, organization
P. AKA atypical hyperplasia, a disorderly proliferation
Dysplasia
Physiologic: N/A
Pathologic: squamous dysplasia of cervix from HPV
E. one cell type replaced with another
P. reprogramming of stem cells, reversible
Metaplasia Physiologic: N/A
Pathologic: stratified squamous cells in bronchial
lining r/t cigarette smoke
E. inadequate oxygenation of tissues
P. decrease in mitochondrial function, decreased
Hypoxia injury production of ATP increases anaerobic metabolism.
eventual cell death.
C.M. hypoxia, cyanosis, cognitive impairment, lethargy
E. normal byproduct of ATP production, will
overwhelm the mitochondria- exhaust intracellular
antioxidants
Free radical and ROS
P. lipid peroxidation, damage proteins, fragment DNA
C.M. development in Alzheimer's, heart disease,
Parkinson's disease, Amyotrophic Lateral Sclerosis