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Exam (elaborations)

USMLE STEP 1 EXAM 2025/2026 QUESTIONS AND ANSWERS 100% PASS

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USMLE STEP 1 EXAM 2025/2026 QUESTIONS AND ANSWERS 100% PASS

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USMLE STEP 1 EXAM 2025/2026
QUESTIONS AND ANSWERS 100% PASS




Hormone to test for menopause. - ANS high FSH



Treatment of Heparin Induced Thrombocytopenia - ANS Direct thrombin inhibitors-
Agatroban

Then protamine sulfate



PT or PTT for Heparin - ANS PTT



PT or PTT for Warfarin - ANS PT



Skin necrosis from warfarin, what do you do? - ANS Give heparin



Antidote to excessive thrombolytics - ANS Aminocaproic acid



Glanzmanns Thrombasthenia - ANS GPIIb/IIIa- platelet adhesion



Bernard soulier - ANS Gp1b



1 @COPYRIGHT 2025/2026 ALLRIGHTS RESERVED.

, Aspirin decreases platelet adehsion, activation or aggregation? - ANS Activation



Drugs that decrease platelet activation - ANS aspirin, toclopidine, clopidogrel- block ADP
receptors



Drugs that decrease aggregation - ANS abciximab, eptifibatide, tirofiban



Why do sulfonamides decrease increase PT in patients on warfarin? - ANS Sulfonamides
displace the weakly but extensively bound warfarin on plasma proteins. This is different
mechanism from cimetidine which increase P450



Onset, peak effect and duration of lispro - ANS onset: 0.3-0.5hrs

peak effect: 1-2 hrs

duration: 2-4hrs



Onset peak effect and duration of regular - ANS onset: 0.5-1hrs

peak effect: 2-4hrs

duration: 5-7hrs



Onset, peak effect and duration of glargine - ANS onset: 1hr

peak effect: no peak

duration>24hrs



What increases insulin release? what decreases insulin release - ANS 1. glucose, amino acids,
sulfonylureas, M-agonists, B2 agonists 2. a2 agonists




2 @COPYRIGHT 2025/2026 ALLRIGHTS RESERVED.
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