EXAM 2025-2026 WITH ORGANIZED
QUESTIONS FULLY SOLVED STEP BY
STEP EXPLANATIONS AND REVIEW
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how does oxidative process contribute to RI? - THE CORRECT
ANSWER-RAS causes impairment of cell membrane and pro-
apotptoic cells release. making cell unstable
what is primary Hypertension? - THE CORRECT ANSWER-Essential or
idiopathic, elevated BP without an identified cause, accounts
for 90 - 95% of all cases of hypertension?
what is secondary hypertension? - THE CORRECT ANSWER-Elevated
BP, labile BP; related to conditions ie kidney dz; resistant to BP
meds
what is significance of Ventricular hypertrophy and HTN? - THE
CORRECT ANSWER-persistent hypertension leads to ventricular
hypertrophy; decrease CO
what comorbidities/conditions does HTN cause? - THE CORRECT
ANSWER-stroke, ischemia, heart failure, aneurysm, hemorrhage
,what is preload? - THE CORRECT ANSWER-volume of blood in
ventricles at end of diastole
what is afterload? - THE CORRECT ANSWER-peripheral resistance
against which the left ventricle must pump
hoe does HTN l/t CHF? - THE CORRECT ANSWER-overwork left
ventricle due to increase pressure; decreased pumping ability of
heart and decreases CO.
identify pathological process of gangrene? - THE CORRECT ANSWER-
form of coagulative necrosis; interruption of blood flow l/t
denaturing cells enzymes and bacterial invasion
three types of gangrene - THE CORRECT ANSWER-dry, wet & gas
what is the major treatment approach for gangrene? - THE
CORRECT ANSWER-removing affective tissue to prevent infection;
treating problem that led to gangrene
why use antibiotic for gangrene? - THE CORRECT ANSWER-to slow
bacterial damage
What are the two major necrotic processes? - THE CORRECT ANSWER-
Coagulative and liquifactive
, What is coagulative necrosis? - THE CORRECT ANSWER-necrosis
caused y interruption of blood flow l/t desrease Ph, and
bacterial growth
what is liquifactive necrosis? - THE CORRECT ANSWER-Caustic
enzymes dissolve and liquify necrotic cell; cottage cheese like
appearance.
Describe dry gangrene - THE CORRECT ANSWER-hypoxia l/t ischemia
l/t last of blood flow l/t coagulative necrosis
Describe wet gangrene - THE CORRECT ANSWER-extensive damage
from bacteria with WBC's that have invaided site produces a
liquid wound
describe gas gangrene - THE CORRECT ANSWER-Presence of
clostridium (aerobic bacteria) releases toxins and destroy
surrounding cell. Most fatal.
Colon cancer inherited vs genetic - THE CORRECT ANSWER-Colon CA
inherited- occurs on gremline
Colon CA genetic occurs on somatic cells
Describe FAP - familial adenomatous polyposis - THE CORRECT
ANSWER-Gene defect on chromosome 1 or 5; involves tumor
suppressor genes, hereditary condition