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Inotrope definition - CORRECT ANSWERS ✔✔Impacts contractility
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Chronotrope definition - CORRECT ANSWERS ✔✔Impacts HR
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Vaspopressor definition - CORRECT ANSWERS ✔✔Increases BP,
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Pressor
Alpha 1 - CORRECT ANSWERS ✔✔Pressor and Inotropy (Phenyl)
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Beta 1 - CORRECT ANSWERS ✔✔Inotropy and Chronotropy (Epi)
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Beta 2 - CORRECT ANSWERS ✔✔Pressor and Bronchodilator
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(Albuterol)
Pressors (Increase BP) list - CORRECT ANSWERS
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✔✔Phenylephrine, Vasopressin, Norepinephrine, Epinephrine, |\ |\ |\ |\
Dopamine
Phenylephrine - CORRECT ANSWERS ✔✔-Receptor: Pure Alpha 1
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-Pressor: XXX |\
-Arterial vasoconstriction (increase in SVR and MAP)
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-Notes: Only IV push option(100mcg=1mL), takes lot of volume,
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No HR effects
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, -Infusion rate: 40-200mcg/min or 0.2-0.2mcg/kg/min
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-Caution for reflex brady
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Vasopressin - CORRECT ANSWERS ✔✔-Receptor: ADH
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-Pressor: XX |\
-Increase SVR and MAP |\ |\ |\ |\
-Notes: retains free H2O, weak pressor, No HR effects, potent
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pressor in septic shock (holds onto free H2O, increases preload)
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-Allows for reduction of other pressors
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-IV dose: 0.01-0.04u/min (usually on/off, don't titrate)
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Norepinephrine - CORRECT ANSWERS ✔✔-Receptor: Beta 1 (at |\ |\ |\ |\ |\ |\ |\ |\
higher doses) = Alpha 1 (potent) > Beta 2
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-Pressor: XXX |\
-HR: XX |\
-Inotrope: XX |\
-Potent Alpha 1 (arterial constriction and increased MAP and SVR)
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-Notes: 1st line in sepsis (assure adequate preload before using)
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-IV dose: 0.05-0.1mcg/kg/min
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-Indications: hypotension, shock, acute pulm edema|\ |\ |\ |\ |\
-Cautions: Myocardial ischemia, Decreased organ perfusion,
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Increased afterload might worsen LV dysfunction
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Epinephrine - CORRECT ANSWERS ✔✔-Receptor: Beta 1 (primary,
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Increase contractility and HR) = Beta 2 > Alpha 1 (secondary,
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arterial and venous constriction, increase MAP and SVR)
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