Pharmacokinetics Exam Questions and Answers 100% Pass

Pharmacokinetics Exam Questions and
Answers 100% Pass


Pharmacokinetics -

[ANSWER]: the study of what happens to the drug(s) in the patients

body after administered. Includes absorption, distribution, metabolism

and excretion.




QUESTION: (ADME) -

[ANSWER]: Absorption, Distribution, Metabolism, Excretion




QUESTION: What does ADME influence? -

[ANSWER]: -the drug levels -kinetics of drug exposure to tissue -

Therefore the performance and pharmacological activity of the drug




QUESTION: Absorption -

,[ANSWER]: the process by which a drug crosses various barriers to

reach the bloodstream




QUESTION: Which route of administration is absorption not

considered a factor? -

[ANSWER]: Intravenous




QUESTION: Bioavailability -

[ANSWER]: the degree to which a drug is absorbed and becomes

available via the general circulation




QUESTION: The two main methods of absorption: -

[ANSWER]: 1. Passive Processes 2. Active Process




QUESTION: Passive Processes (3) -

[ANSWER]: (All require no energy)1. Simple diffusion 2. Facilitated

Diffusion: H2O soluble drugs through pores or channels 3.

, Pinocytosis/Phagocytosis: cells engulfing particles or droplets (less

common)




QUESTION: Active Process -

[ANSWER]: Active Transport: requires energy to move substances

against the concentration gradient




QUESTION: Seven Factors that Affect Drug Absorption -

[ANSWER]: 1. Blood Supply 2. Route of Administration 3. Ionization

4. Size of Drug Molecule 5. Drug Solubility 6. Formulation of the Drug

7. Concentration of the Drug




QUESTION: Factors Affecting the Absorption of Oral Drugs -

[ANSWER]: 1. GIT disease may reduce the number of viili or cause

diarrhea 2. Gut fill and pyloric empting rate may delay transit of drugs

into the small intestine where most of the absorption occurs 3. Drugs