CH. 2 – The Biochemistry of Macromolecules
MEDIUM
1. Proteins, carbohydrates, lipids and nucleic acids are the 4 major groups of organic macromolecules
that are necessary for living cells whether they are Prokaryotes or Eukaryotes. What major
characteristics do these 4 groups share?
a. all have a carbon atom as their backbone
b. each group has nonspecific monomers that are joined together by covalent bonds
c. monomers are bonded to each other via hydrolysis reactions
d. all of these is correct
EASY
2. Match the macromolecule with the correct examples:
Macromolecule Examples
Proteins C a. nucleotide monomers
Carbohydrates D b. fatty acid monomers
Lipids B c. amino acid monomers
Nucleic Acids A d. monosaccharide monomers
2.1 Proteins
EASY
3. What are the major characteristics of a protein?
a. made of amino acid monomers that contain nitrogen
b. each of the 20 naturally occurring amino acids has an amino group, a carboxyl group and a “R=residue”
or side chain
c. the side chain is different for each of the 20 amino acids
D. all of these is correct
MEDIUM
4. How are amino acids classified?
a. names may be abbreviated with five letter words
b. 4 groups of amino acids according to amino group: basic, acidic, nonpolar or uncharged polar
C. names may be abbreviated with a single capital letter
d. all of these is correct
EASY
5. Match the protein structure with the correct description
Protein Structure Description
Primary D a. stable 3-dimensional conformation
Secondary C b. 2 or more tertiary polypeptides joined together
Tertiary A c. alpha helix or beta pleated sheet
Quaternary B d. linear sequence of amino acids joined by peptide bonds
MEDIUM
6. Which of the following correctly describes the two basic biochemical reactions in cells
a. dehydration synthesis and hydrolysis
b. dehydration synthesis adds a molecule of water and hydrolysis removes one
c. dehydration polymerization and hydrolytic degradation
d. oxidation and reduction
, 2
HARD
7. The structure of a secondary or higher protein is dependent upon ____________. Thus this determines the
functionality of the protein.
a. the hydrophobic or hydrophilic nature of the amino acids in the primary structure
b. the electrostatic attractions between the R or side chains of the amino acids in the primary structure
c. the interaction of the sulfhydryl groups that produce disulfide bridges
D. all of these is correct
EASY
8. Denaturation of the secondary or tertiary structure of a protein may be caused by
a. changes in environmental conditions such as temperature or pH
b. may be temporary as in the use of a curling iron on human hair
c. may be permanent as in the use of chemical solutions on human hair
d. usually involves ligands
E. only a, b, and c are correct
MEDIUM
9. Match the protein with its function
Protein Function
Antibody C a. protein in RBCs that transports oxygen throughout the body
Insulin D b. contractile protein needed in muscle cells
Myosin B c. produced by immune system and initiates destruction of pathogens
Hemoglobin A d. hormone that facilitates glucose uptake in cells
2.2 Enzymes
EASY
10. Which of the following statements about enzymes is NOT true?
a. special class of tertiary structure proteins that act as catalysts in biochemical reactions
B. increase the activation energy (Ea) needed to make a normally occurring reaction happen faster
c. when hydrolysis reactions are catalyzed by enzymes, energy needed for cell survival is released
d. living cells cannot use heat to speed up reactions because it would denature proteins so enzymes are
used instead
e. enzymes are highly specific to the substrate to which they can bind
MEDIUM
11. What is the correct order of steps in the use of an enzyme in a biochemical reaction?
1. Induced fit distorts the substrate making it more reactive and lowering Ea
2. Substrate binds to active site of enzyme like a lock and key
3. Substrate converted to product because of change in shape, size and charge
4. Enzyme-substrate binding energy contributes to catalysis
a. 1, 2, 4, 3 B. 2, 1, 4, 3 c. 1, 2, 3, 4 d. 2, 4, 1, 3 e. 2, 3, 1, 4
MEDIUM
1. Proteins, carbohydrates, lipids and nucleic acids are the 4 major groups of organic macromolecules
that are necessary for living cells whether they are Prokaryotes or Eukaryotes. What major
characteristics do these 4 groups share?
a. all have a carbon atom as their backbone
b. each group has nonspecific monomers that are joined together by covalent bonds
c. monomers are bonded to each other via hydrolysis reactions
d. all of these is correct
EASY
2. Match the macromolecule with the correct examples:
Macromolecule Examples
Proteins C a. nucleotide monomers
Carbohydrates D b. fatty acid monomers
Lipids B c. amino acid monomers
Nucleic Acids A d. monosaccharide monomers
2.1 Proteins
EASY
3. What are the major characteristics of a protein?
a. made of amino acid monomers that contain nitrogen
b. each of the 20 naturally occurring amino acids has an amino group, a carboxyl group and a “R=residue”
or side chain
c. the side chain is different for each of the 20 amino acids
D. all of these is correct
MEDIUM
4. How are amino acids classified?
a. names may be abbreviated with five letter words
b. 4 groups of amino acids according to amino group: basic, acidic, nonpolar or uncharged polar
C. names may be abbreviated with a single capital letter
d. all of these is correct
EASY
5. Match the protein structure with the correct description
Protein Structure Description
Primary D a. stable 3-dimensional conformation
Secondary C b. 2 or more tertiary polypeptides joined together
Tertiary A c. alpha helix or beta pleated sheet
Quaternary B d. linear sequence of amino acids joined by peptide bonds
MEDIUM
6. Which of the following correctly describes the two basic biochemical reactions in cells
a. dehydration synthesis and hydrolysis
b. dehydration synthesis adds a molecule of water and hydrolysis removes one
c. dehydration polymerization and hydrolytic degradation
d. oxidation and reduction
, 2
HARD
7. The structure of a secondary or higher protein is dependent upon ____________. Thus this determines the
functionality of the protein.
a. the hydrophobic or hydrophilic nature of the amino acids in the primary structure
b. the electrostatic attractions between the R or side chains of the amino acids in the primary structure
c. the interaction of the sulfhydryl groups that produce disulfide bridges
D. all of these is correct
EASY
8. Denaturation of the secondary or tertiary structure of a protein may be caused by
a. changes in environmental conditions such as temperature or pH
b. may be temporary as in the use of a curling iron on human hair
c. may be permanent as in the use of chemical solutions on human hair
d. usually involves ligands
E. only a, b, and c are correct
MEDIUM
9. Match the protein with its function
Protein Function
Antibody C a. protein in RBCs that transports oxygen throughout the body
Insulin D b. contractile protein needed in muscle cells
Myosin B c. produced by immune system and initiates destruction of pathogens
Hemoglobin A d. hormone that facilitates glucose uptake in cells
2.2 Enzymes
EASY
10. Which of the following statements about enzymes is NOT true?
a. special class of tertiary structure proteins that act as catalysts in biochemical reactions
B. increase the activation energy (Ea) needed to make a normally occurring reaction happen faster
c. when hydrolysis reactions are catalyzed by enzymes, energy needed for cell survival is released
d. living cells cannot use heat to speed up reactions because it would denature proteins so enzymes are
used instead
e. enzymes are highly specific to the substrate to which they can bind
MEDIUM
11. What is the correct order of steps in the use of an enzyme in a biochemical reaction?
1. Induced fit distorts the substrate making it more reactive and lowering Ea
2. Substrate binds to active site of enzyme like a lock and key
3. Substrate converted to product because of change in shape, size and charge
4. Enzyme-substrate binding energy contributes to catalysis
a. 1, 2, 4, 3 B. 2, 1, 4, 3 c. 1, 2, 3, 4 d. 2, 4, 1, 3 e. 2, 3, 1, 4
