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NR 507: ADVANCED PATHOPHYSIOLOGY MIDTERM EXAM QUESTIONS AND ANSWERS

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Asthma Correctanswer~Chronicdiseaseduetobronchoconstrictionandanexcessiveinflammatoryrespo nseinthebronchioles Whatare5s/sofasthma-Correctanswer~coughing wheezing shortnessofbreath rapidbreathing chesttightness Pathophysiologyofasthma(5)-Correctanswer~-airwayinflammation,bronchialhyper reactivityandsmoothmusclespasm -excessmucusproductionandaccumulation -hypertrophyofbronchialsmoothmuscle -airflowobstruction -decreasedalveolarventilation Bronchioles Correctanswer~smallerpassagewaysthatoriginatefromthebronchithatbecomethealveoli

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NR 507: ADVANCED
PATHOPHYSIOLOGY MIDTERM
EXAM QUESTIONS AND ANSWERS


Asthma-
Correctanswer~Chronicdiseaseduetobronchoconstrictionandanexcessiveinflammatoryrespo
nseinthebronchioles



Whatare5s/sofasthma-Correctanswer~coughing

wheezing

shortnessofbreath

rapidbreathing

chesttightness



Pathophysiologyofasthma(5)-Correctanswer~-airwayinflammation,bronchialhyper-
reactivityandsmoothmusclespasm

-excessmucusproductionandaccumulation

-hypertrophyofbronchialsmoothmuscle

-airflowobstruction

-decreasedalveolarventilation



Bronchioles-
Correctanswer~smallerpassagewaysthatoriginatefromthebronchithatbecomethealveoli



3layersofthebronchioles-Correctanswer~innermostlayer

middlelayer-laminapropria

,outermostlayer



laminapropria-Correctanswer~themiddlelayerofthebronchioles



structureofthelaminapropria-
Correctanswer~embeddedwithconnectivetissuecellsandimmunecells



purposeofthelaminapropria-
Correctanswer~whitebloodcellsarepresenttohelpprotecttheairways



Howdoesthelaminapropriaeffectthelungsinregardstoasthma-
Correctanswer~theWBCsprotectivefeaturegoesintooverdrivecausinganinflammatoryrespons
ethatdamageshosttissue



Whatdoestheinnermostlayerofthebronchiolescontain-
Correctanswer~columnarepithelialellsandmucusproducinggobletcells



Whatdoestheoutermostlayerofthebronchiolescontain-Correctanswer~smoothmusclecells



whatdoestheoutermostlayerofthebronchiolesdo-
Correctanswer~controltheairwaysabilitytoconstrictanddilate



alveolarhyperinflation-
Correctanswer~Whenairisunabletomoveoutofthealveolarlikeitshouldduetobronchialwallscoll
apsingaroundpossiblemucusplugthustrappingairinside



howdoeshyperinflationoccur?-
Correctanswer~theongoinginflammatoryprocessofasthmaproducesmucusandpusplugthatthe
bronchialwallscollapsearound

, Effectofhyperinflationofthealveolar-Correctanswer~-
expandedthoraxandhypercapnia(retentionofCO2)

-respiratoryacidosis



Whataretwoanticholinergicdrugsusedforasthma-Correctanswer~tiotropiumandipratropium



Whatdoanticholinergicsdointhelungs?-
Correctanswer~Thesedrugsblocktheeffectsoftheparasympatheticnervoussystem

-increasingbronchodilation



MOAofanticholinergicdrugsforasthma-
Correctanswer~theparasympatheticsystemisstimulatedbythevagalnervetoreleaseacetylcholi
newhichbindstothecholinergicreceptorsoftherespiratorytracttocausebronchialconstriction=d
ecreasedairflow



-
blockingthecholinergicreceptorspreventsacetylcholinebindingpreventingthebronchialconstri
ction



bronchitis-Correctanswer~inflammationofthebronchialtubes



3characteristicsofbronchitis-Correctanswer~bronchialinflammation

hypersecretionofmucus

chronicproductivecoughforatleast3consecutivemonthsforatleast2successiveyears



Perfusion-
Correctanswer~Thesupplyofoxygentoandremovalofwastesfromthecellsandtissuesofthebodya
saresultoftheflowofbloodthroughthecapillaries.



resultsofchronicbronchitis/lowperfusion-Correctanswer~cyanosis

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