Abrams’ Clinical Drug Therapy: Rationales for Nursing Practice (12th Edition, Frandsen) — Complete Test Bank

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abrams' Clinical Drug Therapy: Rationales for
Nursing Practice 12th Edition Frandsen Test
Bank

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,Chapter 1 The Foundation of Pharmacology: Quality and Safety
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A woman has been prescribed paroxetine hyd
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rochloride, which is an antidepressant agent sl sl sl sl sl sl



administered in pill form. The medication is a
1.
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dministered for her obsessive- sl sl sl



compulsive disorder. This medication will pr
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oduce which of the following effects? sl sl sl sl sl



A) Curative
B) Systemic
C) Local
D) Parenteral
Ans: B
Feedback:
Drugs that produce systemic effects are taken
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into the body, circulated through the bloodstre
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am to their sites of action in various body tiss
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ues, and eventually eliminated from the body.
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Curative agents are given to cure a disease pro sl sl sl sl sl sl s l sl



cess. In this case, paroxetine hydrochloride wi
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ll control the symptoms but not cure the disor
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der. Drugs with local effects, such as sunscree
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n and local anesthetics, act mainly at the site
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of application. Paroxetine hydrochloride is no
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t administered parenterally. Parenteral agents
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are administered subcutaneously, intramuscul
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arly, or intravenously. s l s l




A patient has been prescribed an antibiotic. T
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his medication is a naturally occurring substa
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2. nce that has been chemically modified. What
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is another name for this type of medication?
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A) Synthetic drug s l



B) Semisynthetic drug s l



C) Biotechnology drug s l



D) Prototype drug s l



Ans: B
Feedback:

, Semisynthetic drugs (e.g., many antibiotics) a sl sl sl sl sl



re naturally occurring substances that have be
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en chemically modified. Synthetic drugs are
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more standardized in their chemical characteri
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stics, more consistent in their effects, and less
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likely to produce allergic reactions. Biotechno
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logy drugs involve manipulating DNA and R
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NA and recombining genes into hybrid molec
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ules that can be inserted into living organisms.
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Prototype drugs are the first drug of a sl sl sl sl sl sl sl s



lparticular group to be developed. sl sl sl sl




A patient is administered morphine. Morphine
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is a prototypical drug that can be classified in
3.
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different ways. Which of the following classi sl sl sl sl sl s l



fications applies to morphine? sl sl sl



A) Central nervous system depressant sl sl sl



B) Central nervous system stimulant sl sl sl



C) Anti-inflammatory
D) Antihypertensive
Ans: A
Feedback:
Drugs are classified according to their effects
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on particular body systems, their therapeutic u
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ses, and their chemical characteristics. For exa
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mple, morphine can be classified as a central n
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ervous system depressant and a narcotic or op
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ioid analgesic. A central nervous system stimul
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ant increases attention and raises mood. An a
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nti-
inflammatory agent decreases inflammation at sl sl sl sl sl



the site of tissue or joint inflammation. An ant
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ihypertensive agent reduces blood pressure. sl sl sl sl




A patient is administered amoxicillin (Amoxi
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l). The generic name of this medication indic
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ates that it belongs to which drug group?
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A) Selective serotonin reuptake inhibitors s l s l sl



B) Diuretics
C) Penicillins
D) ACE inhibitors s l



Ans: C

, Feedback:
The generic name often indicates the drug gro
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up (e.g., drugs with generic names ending in
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“cillin” are penicillins). Selective serotonin re
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uptake inhibitors are medications that have an
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tidepressant effects; SSRI is a broad classifica sl sl sl sl sl s l



tion, not a generic name. Diuretics are medic
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ations that increase urine output; diuretic is a
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broad classification, not a generic name. ACE
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inhibitor is the broad classification for the an sl sl sl sl s l s l s l



giotensin-
converting enzyme inhibitors, not the generic sl sl sl sl sl sl



name.

The administration of diphenhydramine (Bena
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dryl), which is an over-the-
5.
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counter medication, is regulated by which gov
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ernment agency? sl



A) Public Health Service sl sl



B) Federal Trade Commission sl s l



Occupational Safety and Health
C)
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Administration
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D) Food and Drug Administration
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Ans: D
Feedback:
The Food and Drug Administration approves
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drugs for over-the-
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counter availability, including the transfer of
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drugs from prescription to OTC status, and
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may require clinical trials to determine the sa
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fety and effectiveness of OTC use. The Publi
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c Health Service is regulated by the state to
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maintain the health of individual citizens of t s l sl sl sl sl sl sl



he state. The Federal Trade Commission reg
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ulates imports and exports throughout the na
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tion.
The Occupational Safety and Health Adm
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inistration regulates safety within the wor sl sl sl sl s l



kplace.

The administration of anabolic steroids is
6.
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regulated by which of the following laws? sl sl sl sl sl sl



A) The Food, Drug, and Cosmetic Act of 1938
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The Comprehensive Drug Abuse Prevention
B)
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and Control Act
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C) The Harrison Narcotic Act
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