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NURS 615 Exam 3 (65 Questions) – Pharmacology, Endocrine, Cardio, Diabetes – Maryville University

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This detailed exam preparation document contains 65 comprehensive questions and answers tailored for NURS 615 – Advanced Pharmacology during the 2025/2026 academic year. The content spans major therapeutic areas, including corticosteroids, NSAIDs, opioids, antidiabetic medications (oral and insulin-based), thyroid and antithyroid drugs, cardiovascular treatments such as ACE inhibitors, ARBs, beta blockers, calcium channel blockers, statins, as well as heart failure medications, antiarrhythmics, anticoagulants, and lipid-lowering agents. Each answer includes mechanisms of action, adverse effects, clinical uses, monitoring parameters, and important prescribing considerations. This study guide is ideal for students enrolled in: Family Nurse Practitioner (FNP) Adult-Gerontology Nurse Practitioner (AGNP) Doctor of Nursing Practice (DNP) PharmD Physician Assistant (PA) programs It is also highly beneficial for medical students reviewing pharmacology content or preparing for clinical exams. Presented in a clear Q&A format, the material supports efficient review, memorization, and application of core pharmacological principles. It is a high-scoring, exam-aligned resource designed to boost confidence and performance in pharmacology-based assessments. Keywords: NURS 615, advanced pharmacology, corticosteroids, NSAIDs, opioids, antidiabetic medications, insulin therapy, thyroid drugs, ACE inhibitors, beta blockers, ARBs, calcium channel blockers, statins, anticoagulants, antiarrhythmic drugs, heart failure treatment, drug interactions, nurse practitioner exam review, graduate pharmacology

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NURS 615 Exam 3 – Maryville 2025/2026
Exam Questions and Answers | A+ Score
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corticosteroid drugs - 🧠 ANSWER ✔✔prednisone, methylprednisolone,

dexamethasone, topical such as hydrocortisone, and then joint injections

for pain


MOA of corticosteroids drugs - 🧠 ANSWER ✔✔drugs that suppress

inflammation by mimicking glucocorticoid hormones




Inhibit interleikin one, tumor necrosis factor and other cytokines, impairs

phagocytosis, impairs lymphocytes, and inhibits tissue repair


indications for cortocosteriod use - 🧠 ANSWER ✔✔Allergy or

hypersensitivity, respiratory, shock, rheumatology, neurology, hepatic,

neoplastic... basicly every organ is covered if there is an issue.

,withdrawal from corticorsteriod symptoms - 🧠 ANSWER ✔✔malaise,

myalgia, headache, nausea, fevers, hypotension and relapse of symptoms

(pain, inflammation, ashtma)

what must you do with corticosteriods to prevent withdrawal - 🧠 ANSWER

✔✔Must taper them down, you can have possible adrenal crisis if you do

not.


corticosteriod considerations - 🧠 ANSWER ✔✔suppression patients

response to infections- no live viral vaccines, and have increased

susceptibility to disease.




If used over 6 months: Increase blood glucose, impair immune function (get

vaccines) , impair wound healing, GI complaints (report black tarry stools) ,

osteoporosis (decreases calcium), anxiety/insomnia, sodium & fluid

retention 9monitor weight and fluid retention)




If on 1gram or more also prescribe PPI (omeprazole) to prevent PUD




contraindicated with active infection and hypersensitivity

,What are the adverse effects of corticosteroids if administered for six

months or more? - 🧠 ANSWER ✔✔The main thing you want to worry about

is osteoporosis




It can also worsen diabetic control




Patients should report any tarry black stools or abdominal pain.


NSAIDS - 🧠 ANSWER ✔✔nonsteroidal anti-inflammatory drugs




Ibprofen, aspirin, torsdol, naproxin, Mobic


Arachidonic Acid Cascade - 🧠 ANSWER ✔✔Cell membrane ►

Arachinidonic acid ► Cycloxygenerase (COX)► prostaglandin's




Or




Cell membrane ► Arachinidonic acid ► Lipoxygenase► Leukotrines



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, NSAID mechanism of action - 🧠 ANSWER ✔✔• NSAIDs inhibit the

enzymes COX I and II

• Results in reduction in formation of prostaglandin precursors and

thromboxanes from arachidonic acid




COX1- ibuprofen, naproxen, aspirin, when this is inhibited you are also

inhibiting the prostaglandins that protect the stomach




COX2 - celebrex more stomach proctective


Drug interactions with NSAIDS - 🧠 ANSWER ✔✔Pretty much anything that

is highly protien bound. Do not give together with




ACE inhibitors - counteracts antihypertensive effect




BetaBlockers - counteracts antihypertensive effect




lithium - increases lithium levels
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