TEST BANK McCance Huether’s Pathophysiology The Biologic Basis for Disease in Adults and Children (9TH) by Julia Rogers + NCLEX Case Studies with Answers

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PATHOPHYSIOLOGY
The Biologic Basis For Disease In Adults
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And Children
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8TH EDITION BY KATHRYN L. MC
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CANCE

,McCance:vnPathophysiology:vnThevnBiologicvnBasisvnforvnDiseasevninvnAdultsvnandvnChildrenvn(8thvnEdition)vn
TESTvnBANK

CONTENTS:
Chaptervn01:vnCellularvnBiology
Chaptervn02:vnAlteredvnCellularvnandvnTissuevnBiology:vnEnvironmentalvnAgents
Chaptervn03:vnThevnCellularvnEnvironment:vnFluidsvnandvnElectrolytes,vnAcidsvnandvnBases
Chaptervn04:vnGenesvnandvnGeneticvnDiseases
Chaptervn05:vnGenes,vnEnvironment-Lifestyle,vnandvnCommonvnDiseases
Chaptervn06:vnEpigeneticsvnandvnDisease
Chaptervn07:vnInnatevnImmunity:vnInflammationvnandvnWoundvnHealing
Chaptervn08:vnAdaptivevnImmunity
Chaptervn09:vnAlterationsvninvnImmunityvnandvnInflammation
Chaptervn10:vnInfection
Chaptervn11:vnStressvnandvnDisease
Chaptervn12:vnCancervnBiology
Chaptervn13:vnCancervnEpidemiology
Chaptervn14:vnCancervninvnChildren
Chaptervn15:vnStructurevnandvnFunctionvnofvnthevnNeurologicvnSystem
Chaptervn16:vnPain,vnTemperaturevnRegulation,vnSleep,vnandvnSensoryvnFunction
Chaptervn17:vnAlterationsvninvnCognitivevnSystems,vnCerebralvnHemodynamics,vnandvnMotorvnFunction
Chaptervn18:vnDisordersvnofvnthevnCentralvnandvnPeripheralvnNervousvnSystemsvnandvnthevnNeuromuscularvnJunction
Chaptervn19:vnNeurobiologyvnofvnSchizophrenia,vnMoodvnDisorders,vnandvnAnxietyvnDisorders
Chaptervn20:vnAlterationsvnofvnNeurologicvnFunctionvninvnChildren
Chaptervn21:vnMechanismsvnofvnHormonalvnRegulation
Chaptervn22:vnAlterationsvnofvnHormonalvnRegulation
Chaptervn23:vnObesityvnandvnDisordersvnofvnNutrition
Chaptervn24:vnStructurevnandvnFunctionvnofvnthevnReproductivevnSystems
Chaptervn25:vnAlterationsvnofvnthevnFemalevnReproductivevnSystem
Chaptervn26:vnAlterationsvnofvnthevnMalevnReproductivevnSystem
Chaptervn27:vnSexuallyvnTransmittedvnInfections
Chaptervn28:vnStructurevnandvnFunctionvnofvnthevnHematologicvnSystem
Chaptervn29:vnAlterationsvnofvnErythrocytes,vnPlatelets,vnandvnHemostaticvnFunction
Chaptervn30:vnAlterationsvnofvnLeukocytevnandvnLymphoidvnFunction
Chaptervn31:vnAlterationsvnofvnHematologicvnFunctionvninvnChildren
Chaptervn32:vnStructurevnandvnFunctionvnofvnthevnCardiovascularvnandvnLymphaticvnSystems
Chaptervn33:vnAlterationsvnofvnCardiovascularvnFunction
Chaptervn34:vnAlterationsvnofvnCardiovascularvnFunctionvninvnChildren
Chaptervn35:vnStructurevnandvnFunctionvnofvnthevnPulmonaryvnSystem
Chaptervn36:vnAlterationsvnofvnPulmonaryvnFunction
Chaptervn37:vnAlterationsvnofvnPulmonaryvnFunctionvninvnChildren
Chaptervn38:vnStructurevnandvnFunctionvnofvnthevnRenalvnandvnUrologicvnSystems
Chaptervn39:vnAlterationsvnofvnRenalvnandvnUrinaryvnTractvnFunction
Chaptervn40:vnAlterationsvnofvnRenalvnandvnUrinaryvnTractvnFunctionvninvnChildren
Chaptervn41:vnStructurevnandvnFunctionvnofvnthevnDigestivevnSystem
Chaptervn42:vnAlterationsvnofvnDigestivevnFunction
Chaptervn43:vnAlterationsvnofvnDigestivevnFunctionvninvnChildren
Chaptervn44:vnStructurevnandvnFunctionvnofvnthevnMusculoskeletalvnSystem
Chaptervn45:vnAlterationsvnofvnMusculoskeletalvnFunction
Chaptervn46:vnAlterationsvnofvnMusculoskeletalvnFunctionvninvnChildren
Chaptervn47:vnStructure,vnFunction,vnandvnDisordersvnofvnthevnIntegument
Chaptervn48:vnAlterationsvnofvnthevnIntegumentvninvnChildren
Chaptervn49:vnShock,vnMultiplevnOrganvnDysfunctionvnSyndrome,vnandvnBurnsvninvnAdults
Chaptervn50:vnShock,vnMultiplevnOrganvnDysfunctionvnSyndrome,vnandvnBurnsvninvnChildren

, McCance:vnPathophysiology:vnThevnBiologicvnBasisvnforvnDiseasevninvnAdultsvnandvnChildrenvn(8thvnEdition)vnTEST
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Partvn1:vnCENTRALvnCONCEPTSvnOFvnPATHOPHYSIOLOGY:vnCELLSvnANDvnTISSUE
SvnUnitvnI:vnTHEvnCELL

CHAPTERvn01:vnCELLULARvnBIOLOGY

MULTIPLEvnCHOICE

1. Whichvnstatementvnbestvndescribesvnthevncellularvnfunctionvnofvnmetabolicvnabsorption?
a. Cellsvncanvnproducevnproteins.
b. Cellsvncanvnsecretevndigestivevnenzym
es.
c. Cellsvncanvntakevninvnandvnusevnnutrient
s.
d. Cellsvncanvnsynthesizevnfats.

ANS:v n C
Invnmetabolicvnabsorption,vnallvncellsvntakevninvnandvnusevnnutrientsvnandvnothervnsubstancesvnfromvnth
eirvnsurroundings.vnThevnremainingvnoptionsvnarevnnotvninclusivevninvntheirvndescriptionsvnofvncellularvn
metabolicvnabsorption.

PTS:v n v n 1 DIF: CognitivevnLevel:vnRemembering

2. Wherevnisvnmostvnofvnavncell’svngeneticvninformation,vnincludingvnRNAvnandvnDNA,vncontained?
a. Mitochondria
b. Ribosome
c. Nucleolus
d. Lysosome

ANS:v n C
Thevnnucleusvncontainsvnthevnnucleolus,vnavnsmallvndensevnstructurevncomposedvnlargelyvnofvnRNA,vn
mostvnofvnthevncellularvnDNA,vnandvnthevnDNA-
bindingvnproteins,vnsuchvnasvnthevnhistones,vnwhichvnregulatevnitsvnactivity.vnThevnmitochondriavnarevn
responsiblevnforvncellularvnrespirationvnandvnenergyvnproduction.
Ribosomes’vnchiefvnfunctionvnisvntovnprovidevnsitesvnforvncellularvnproteinvnsynthesis.vnLysosomesvnfun
ctionvnasvnthevnintracellularvndigestivevnsystem.

PTS:v n v n 1 DIF: CognitivevnLevel:vnRemembering

3. Whichvncomponentvnofvnthevncellvnproducesvnhydrogenvnperoxidevn(H2O2)vnbyvnusingvnoxygenvntovn
removevnhydrogenvnatomsvnfromvnspecificvnsubstratesvninvnanvnoxidativevnreaction?
a. Lysosomes
b. Peroxisomes
c. Ribosomes
d. Endosome

ANS:v n B

, McCance:vnPathophysiology:vnThevnBiologicvnBasisvnforvnDiseasevninvnAdultsvnandvnChildrenvn(8thvnEdition)vnTEST
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Peroxisomesvnarevnsovnnamedvnbecausevntheyvnusuallyvncontainvnenzymesvnthatvnusevnoxygenvntovnre
movevnhydrogenvnatomsvnfromvnspecificvnsubstratesvninvnanvnoxidativevnreactionvnthatvnproducesvnH2
O2,vnwhichvnisvnavnpowerfulvnoxidantvnandvnpotentiallyvndestructivevnifvnitvnaccumulatesvnorvnescapesvn
fromvnperoxisomes.
RibosomesvnarevnRNA-
proteinvncomplexesvn(nucleoproteins)vnthatvnarevnsynthesizedvninvnthevnnucleolusvnandvnsecretedvnint
ovnthevncytoplasmvnthroughvnporesvninvnthevnnuclearvnenvelopevncalledvnnuclearvnporevncomplexes.vnL
ysosomesvnarevnsaclikevnstructuresvnthatvnoriginatevnfromvnthevnGolgivncomplexvnandvncontainvnmorevnt
hanvn40vndigestivevnenzymesvncalledvnhydrolases,vnwhichvncatalyzevnbondsvninvnproteins,vnlipids,vnnu
cleicvnacids,vnandvncarbohydrates.vnAnvnendosomevnisvnavnvesicalvnthatvnhasvnbeenvnpinchedvnoffvnfro
mvnthevncellularvnmembrane.

PTS:v n v n 1 DIF: CognitivevnLevel:vnRemembering

4. Whichvncellvncomponentvnisvncapablevnofvncellularvnautodigestionvnwhenvnitvnisvnreleasedvnduringvncellvninju
ry?
a. Ribosome
b. Golgivncomplex
c. Smoothvnendoplasmicvnreticulu
m
d. Lysosomes

ANS:v n D
Thevnlysosomalvnmembranevnactsvnasvnavnprotectivevnshieldvnbetweenvnthevnpowerfulvndigestivevnenz
ymesvnwithinvnthevnlysosomevnandvnthevncytoplasm,vnpreventingvntheirvnleakagevnintovnthevncytoplas
micvnmatrix.vnDisruptionvnofvnthevnmembranevnbyvnvariousvntreatmentsvnorvncellularvninjuryvnleadsvnto
vnavnreleasevnofvnthevnlysosomalvnenzymes,vnwhichvncanvnthenvnreactvnwithvntheirvnspecificvnsubstrates,

vncausingvncellularvnself-

vndigestion.vnThevnchiefvnfunctionvnofvnavnribosomevnisvntovnprovidevnsitesvnforvncellularvnproteinvnsynth

esis.vnThevnGolgivncomplexvnisvnavnnetworkvnofvnflattened,vnsmoothvnvesiclesvnandvnmembranesvnoften
vnlocatedvnnearvnthevncellvnnucleus.vnThevnsmoothvnendoplasmicvnreticulumvnisvninvolvedvninvnsteroidvn

hormonevnproductionvnandvnremovingvntoxicvnsubstancesvnfromvnthevncell.

PTS:v n v n 1 DIF: CognitivevnLevel:vnRemembering

5. WhichvncAMP-mediatedvnresponsevnisvnrelatedvntovnantidiureticvnhormone?
a. Increasedvnheartvnratevnandvnforcevnofvncontract
ion
b. Secretionvnofvncortisol
c. Increasedvnretentionvnofvnwater
d. Breakdownvnofvnfat

ANS:v n C
Antidiureticvnhormonevnleadsvntovnincreasedvnretentionvnofvnwatervninvnthevnbody.vnEpinephrinevncaus
esvnincreasesvninvnheartvnratevnandvnforcevnofvncontraction.vnIncreasedvncortisolvnsecretionvnisvnduevntovn
ACTH.vnBreakdownvnofvnfatvnisvnduevntovnglucagon.

PTS:v n v n 1 DIF: CognitivevnLevel:vnRemembering

6. DuringvnwhichvnphasevnofvnthevncellvncyclevnisvnDNAvnsynthesized?
a. G1
b. S
c. G2