PTCB - Drug Interactions (Top 20) Questions and Answers | Latest Version | 2025/2026 | Correct & Verified

PTCB - Drug Interactions (Top 20) Questions and Answers | Latest Version | 2025/2026 | Correct & Verified Which interaction occurs when warfarin is taken with aspirin? Increased risk of bleeding. What is the effect of combining ACE inhibitors with potassium-sparing diuretics? Hyperkalemia (high potassium levels). Which adverse effect may result from taking digoxin with loop diuretics? Increased risk of digoxin toxicity due to low potassium. What happens if a patient takes statins with grapefruit juice? Increased statin levels, risk of muscle toxicity (myopathy). Which interaction is common between MAO inhibitors and tyramine-rich foods? Hypertensive crisis. 2 What is the result of combining sildenafil with nitrates? Severe hypotension. Which risk increases when lithium is taken with NSAIDs? Lithium toxicity. What happens when theophylline is combined with ciprofloxacin? Increased theophylline levels, risk of toxicity. Which adverse reaction can occur if anticoagulants are combined with NSAIDs? Increased bleeding risk. What is the effect of taking metformin with contrast dye? Risk of lactic acidosis. Which interaction occurs when combining warfarin with antibiotics like erythromycin? Increased anticoagulant effect, higher bleeding risk. 3 What is the result of taking digoxin with verapamil? Increased digoxin levels, risk of toxicity. Which adverse effect can occur when combining SSRIs with MAO inhibitors? Serotonin syndrome. What is the effect of combining amiodarone with warfarin? Increased anticoagulant effect, risk of bleeding. Which interaction occurs between calcium supplements and tetracyclines? Reduced absorption of tetracyclines. What happens if a patient takes potassium supplements with ACE inhibitors? Hyperkalemia. Which adverse effect may result from combining phenytoin with valproic acid? Increased risk of phenytoin toxicity or decreased seizure control. 4 What is the effect of combining digoxin with quinidine? Increased digoxin levels, risk of toxicity. Which interaction occurs between statins and fibrates? Increased risk of myopathy and rhabdomyolysis. What is the effect of combining benzodiazepines with alcohol? Enhanced CNS depression, risk of sedation and respiratory depression. Which adverse reaction may occur when combining sulfonylureas with fluoroquinolones? Hypoglycemia. What happens if a patient takes warfarin with vitamin K-rich foods? Reduced anticoagulant effect. Which interaction occurs when combining