PTCB Exam: Federal Requirements
Questions and Answers | Latest
Version | 2025/2026 | Correct & Verified
How often must pharmacies complete an inventory of controlled substances under federal law?
✔✔ Every 2 years (biennially).
Which act created the five schedules of controlled substances?
✔✔ Controlled Substances Act of 1970.
What is the maximum number of refills allowed for a Schedule II controlled substance?
✔✔ Zero refills.
Which controlled substance schedule includes cough syrups with small amounts of codeine?
✔✔ Schedule V.
What must be written on a prescription for a controlled substance in addition to the patient and
drug information?
✔✔ The prescriber’s DEA number.
1
,Which controlled substance schedule has no accepted medical use in the United States?
✔✔ Schedule I.
Which act requires child-resistant packaging for most prescription medications?
✔✔ Poison Prevention Packaging Act of 1970.
What is the maximum number of refills allowed for Schedule III and Schedule IV prescriptions?
✔✔ Up to 5 refills within 6 months.
What federal law requires pharmacists to provide counseling to Medicaid patients?
✔✔ OBRA ’90 (Omnibus Budget Reconciliation Act of 1990).
Which government agency regulates prescription drug labeling?
✔✔ Food and Drug Administration (FDA).
What is the maximum day supply allowed for an emergency oral prescription of a Schedule II
drug?
2
, ✔✔ Enough for 72 hours.
What is required when ordering Schedule II controlled substances?
✔✔ DEA Form 222.
Which act requires medications to be both safe and effective before approval?
✔✔ Kefauver-Harris Amendment of 1962.
What type of recall is issued when a product could cause serious harm or death?
✔✔ Class I recall.
Which DEA form is used to report theft or loss of controlled substances?
✔✔ DEA Form 106.
Which DEA form is used to register a pharmacy with the DEA?
✔✔ DEA Form 224.
How long must controlled substance records be maintained under federal law?
3
Questions and Answers | Latest
Version | 2025/2026 | Correct & Verified
How often must pharmacies complete an inventory of controlled substances under federal law?
✔✔ Every 2 years (biennially).
Which act created the five schedules of controlled substances?
✔✔ Controlled Substances Act of 1970.
What is the maximum number of refills allowed for a Schedule II controlled substance?
✔✔ Zero refills.
Which controlled substance schedule includes cough syrups with small amounts of codeine?
✔✔ Schedule V.
What must be written on a prescription for a controlled substance in addition to the patient and
drug information?
✔✔ The prescriber’s DEA number.
1
,Which controlled substance schedule has no accepted medical use in the United States?
✔✔ Schedule I.
Which act requires child-resistant packaging for most prescription medications?
✔✔ Poison Prevention Packaging Act of 1970.
What is the maximum number of refills allowed for Schedule III and Schedule IV prescriptions?
✔✔ Up to 5 refills within 6 months.
What federal law requires pharmacists to provide counseling to Medicaid patients?
✔✔ OBRA ’90 (Omnibus Budget Reconciliation Act of 1990).
Which government agency regulates prescription drug labeling?
✔✔ Food and Drug Administration (FDA).
What is the maximum day supply allowed for an emergency oral prescription of a Schedule II
drug?
2
, ✔✔ Enough for 72 hours.
What is required when ordering Schedule II controlled substances?
✔✔ DEA Form 222.
Which act requires medications to be both safe and effective before approval?
✔✔ Kefauver-Harris Amendment of 1962.
What type of recall is issued when a product could cause serious harm or death?
✔✔ Class I recall.
Which DEA form is used to report theft or loss of controlled substances?
✔✔ DEA Form 106.
Which DEA form is used to register a pharmacy with the DEA?
✔✔ DEA Form 224.
How long must controlled substance records be maintained under federal law?
3
