PACOP Violet: Biopharmaceutics
Questions and Answers | Latest
Version | 2025/2026 | Correct & Verified
The study of how the dosage form influences drug absorption is called:
a. Pharmacology
✔✔ b. Biopharmaceutics
c. Pharmacogenomics
d. Toxicology
Which parameter best describes the rate and extent of drug absorption?
a. Clearance
✔✔ b. Bioavailability
c. Half-life
d. Volume of distribution
What does AUC represent in pharmacokinetics?
a. Amount of drug in urine
b. Volume of drug distribution
1
,✔✔ c. Total drug exposure over time
d. Rate of drug elimination
The "first-pass effect" primarily occurs in which organ?
✔✔ a. Liver
b. Kidney
c. Lung
d. Heart
Which type of absorption occurs through passive diffusion?
a. Carrier-mediated transport
✔✔ b. Concentration gradient-driven movement
c. Active uptake
d. Endocytosis
The time required to reach peak plasma concentration is referred to as:
a. Bioequivalence
✔✔ b. Tmax
2
,c. Cmax
d. Half-life
What does Cmax represent?
a. Time to peak concentration
✔✔ b. Maximum drug concentration in plasma
c. Total exposure
d. Drug clearance
Drugs administered sublingually bypass which metabolic process?
✔✔ a. First-pass metabolism
b. Protein binding
c. Active transport
d. Passive diffusion
Which factor increases gastric emptying time?
a. Liquids
b. Exercise
3
, ✔✔ c. High-fat meal
d. Stress
What is the fraction of the unchanged drug reaching systemic circulation called?
a. Distribution
b. Absorption
✔✔ c. Absolute bioavailability
d. Clearance
Relative bioavailability compares:
a. Drug to metabolite ratio
✔✔ b. Two different formulations of the same drug
c. Plasma vs urine concentrations
d. Intravenous vs rectal routes
What is the primary site of drug absorption in the GIT?
a. Stomach
✔✔ b. Small intestine
4
Questions and Answers | Latest
Version | 2025/2026 | Correct & Verified
The study of how the dosage form influences drug absorption is called:
a. Pharmacology
✔✔ b. Biopharmaceutics
c. Pharmacogenomics
d. Toxicology
Which parameter best describes the rate and extent of drug absorption?
a. Clearance
✔✔ b. Bioavailability
c. Half-life
d. Volume of distribution
What does AUC represent in pharmacokinetics?
a. Amount of drug in urine
b. Volume of drug distribution
1
,✔✔ c. Total drug exposure over time
d. Rate of drug elimination
The "first-pass effect" primarily occurs in which organ?
✔✔ a. Liver
b. Kidney
c. Lung
d. Heart
Which type of absorption occurs through passive diffusion?
a. Carrier-mediated transport
✔✔ b. Concentration gradient-driven movement
c. Active uptake
d. Endocytosis
The time required to reach peak plasma concentration is referred to as:
a. Bioequivalence
✔✔ b. Tmax
2
,c. Cmax
d. Half-life
What does Cmax represent?
a. Time to peak concentration
✔✔ b. Maximum drug concentration in plasma
c. Total exposure
d. Drug clearance
Drugs administered sublingually bypass which metabolic process?
✔✔ a. First-pass metabolism
b. Protein binding
c. Active transport
d. Passive diffusion
Which factor increases gastric emptying time?
a. Liquids
b. Exercise
3
, ✔✔ c. High-fat meal
d. Stress
What is the fraction of the unchanged drug reaching systemic circulation called?
a. Distribution
b. Absorption
✔✔ c. Absolute bioavailability
d. Clearance
Relative bioavailability compares:
a. Drug to metabolite ratio
✔✔ b. Two different formulations of the same drug
c. Plasma vs urine concentrations
d. Intravenous vs rectal routes
What is the primary site of drug absorption in the GIT?
a. Stomach
✔✔ b. Small intestine
4
