Page |1
HESI Pharmacology Practice Exam
Questions and Correct Answers/ Latest
Update / Already Graded
Following the administration of sublingual nitroglycerin to a client
experiencing an acute anginal attack, which assessment finding
indicates to the nurse that the desired effect has been achieved?
A. Client states chest pain is relieved
B. Client's pulse decreases from 120 to 90
C. Client's systolic blood pressure decreases from 180 to 90
D. Clients SaO2 level increases from 92% to 96%
Ans: A. nitroglycerin reduces mycocardial oxygen consumption
which decreases ischemia and reduces chest pain
A client with hyperlipidemia recieves a prescription for niacin (niaspan).
which client teaching is most important for the nurse to provide
a. expected duration of flushing
b. symptoms of hyperglycemia
c. diets that minimize gi irritation
d. comfort measure for pruritis
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Ans: A. flushing of the face and neck, lasting up to an hour, is a
frequent reason for discontinuing niacin. inclusion of this effect
in clietn teaching may promote compliance in taking the med.
When assessing an adolescent who recently overdosed on
acetaminophen (tylonel), it is most important for the nurse to assess
for pain in which area of the body
a. flank
b. abdomen
c. chest
d. head
Ans: B. acetaminophen toxicisty an result in liver damage;
therefore, it is especially important for the nurse to assess for
pain in the right upper quadrant of the abdomen (which might
indicated liver damage)
A client is admitted to the coronary care unit with a medical diagnosis
of acute myocardial infarction. which medication prescription
decreases both preload and afterload
a. nitroglycerin
b. propranolol
c. propranolol
All rights reserved © 2025/ 2026 |
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d. captopril
Ans: A. nitroglycerin is a nitrate that causes peripheral
vasodilation and decreases contractility, thereby decreasing
both preload and afterload
A client is being treated for hyperthyroidism with propylthiouracil
(PTU). The nurse knows that the action of this drug is to
A. decrease the amount of the thyroid-stimulating hormone circulating
in the blood
B. increase the amount of thyroid-stimulating hormone circulating in
the blood
C. increase the amount of T4 and decrease the amount of T3 produced
by the thyroid
D. inhibit synthesis of T3 and T4 by the thyroid gland
Ans: D. PTU is an adjunct therapy used to control
hyperthyroidism by inhibiting production of thyroid hormones.
It is often prescribed in prep for thyroidectomy or radioactive
iodine therapy
Which change in data indicates to the nurse the desired effect of the
angiotensin II receptor antagonist has been achieved
A. Dependent edema reduced form +3 to +1
All rights reserved © 2025/ 2026 |
, Page |4
B. Serum HDL increased from 35 to 55mg/dl
C. PUlse rate reduced from 150 to 90 beats/min
D. Blood pressure reducedf rom 160/90 to 130.80
Ans: D. angiotensin II receptor antagonist (blocker), prescribed
from treatment of HTN. The desired effect is a decrease in
blood pressure.
Which instructions should the nurse give to a female client who just
recieved a prescription for oral metronidazole (flagyl) for treatment of
trichomonas vaginalis (select all that apply)
A. increase fluid intake, especially cranberry juice
B. Do not abruptly discontinue the medication; taper use
C. Check blood pressure daily to detect hypertension
D. Avoid drinking alcohol while taking this medication
E. Use condoms until treatment is completed
F. Ensure that all sexual partners are treated at the same time
Ans: ADEF
The nurse is transcribing a new prescription for spironolactone
(aldactone) for a client who receives an angiotensin-converting
enzyme inhibitor. Which action should the nurse implement
All rights reserved © 2025/ 2026 |
HESI Pharmacology Practice Exam
Questions and Correct Answers/ Latest
Update / Already Graded
Following the administration of sublingual nitroglycerin to a client
experiencing an acute anginal attack, which assessment finding
indicates to the nurse that the desired effect has been achieved?
A. Client states chest pain is relieved
B. Client's pulse decreases from 120 to 90
C. Client's systolic blood pressure decreases from 180 to 90
D. Clients SaO2 level increases from 92% to 96%
Ans: A. nitroglycerin reduces mycocardial oxygen consumption
which decreases ischemia and reduces chest pain
A client with hyperlipidemia recieves a prescription for niacin (niaspan).
which client teaching is most important for the nurse to provide
a. expected duration of flushing
b. symptoms of hyperglycemia
c. diets that minimize gi irritation
d. comfort measure for pruritis
All rights reserved © 2025/ 2026 |
, Page |2
Ans: A. flushing of the face and neck, lasting up to an hour, is a
frequent reason for discontinuing niacin. inclusion of this effect
in clietn teaching may promote compliance in taking the med.
When assessing an adolescent who recently overdosed on
acetaminophen (tylonel), it is most important for the nurse to assess
for pain in which area of the body
a. flank
b. abdomen
c. chest
d. head
Ans: B. acetaminophen toxicisty an result in liver damage;
therefore, it is especially important for the nurse to assess for
pain in the right upper quadrant of the abdomen (which might
indicated liver damage)
A client is admitted to the coronary care unit with a medical diagnosis
of acute myocardial infarction. which medication prescription
decreases both preload and afterload
a. nitroglycerin
b. propranolol
c. propranolol
All rights reserved © 2025/ 2026 |
, Page |3
d. captopril
Ans: A. nitroglycerin is a nitrate that causes peripheral
vasodilation and decreases contractility, thereby decreasing
both preload and afterload
A client is being treated for hyperthyroidism with propylthiouracil
(PTU). The nurse knows that the action of this drug is to
A. decrease the amount of the thyroid-stimulating hormone circulating
in the blood
B. increase the amount of thyroid-stimulating hormone circulating in
the blood
C. increase the amount of T4 and decrease the amount of T3 produced
by the thyroid
D. inhibit synthesis of T3 and T4 by the thyroid gland
Ans: D. PTU is an adjunct therapy used to control
hyperthyroidism by inhibiting production of thyroid hormones.
It is often prescribed in prep for thyroidectomy or radioactive
iodine therapy
Which change in data indicates to the nurse the desired effect of the
angiotensin II receptor antagonist has been achieved
A. Dependent edema reduced form +3 to +1
All rights reserved © 2025/ 2026 |
, Page |4
B. Serum HDL increased from 35 to 55mg/dl
C. PUlse rate reduced from 150 to 90 beats/min
D. Blood pressure reducedf rom 160/90 to 130.80
Ans: D. angiotensin II receptor antagonist (blocker), prescribed
from treatment of HTN. The desired effect is a decrease in
blood pressure.
Which instructions should the nurse give to a female client who just
recieved a prescription for oral metronidazole (flagyl) for treatment of
trichomonas vaginalis (select all that apply)
A. increase fluid intake, especially cranberry juice
B. Do not abruptly discontinue the medication; taper use
C. Check blood pressure daily to detect hypertension
D. Avoid drinking alcohol while taking this medication
E. Use condoms until treatment is completed
F. Ensure that all sexual partners are treated at the same time
Ans: ADEF
The nurse is transcribing a new prescription for spironolactone
(aldactone) for a client who receives an angiotensin-converting
enzyme inhibitor. Which action should the nurse implement
All rights reserved © 2025/ 2026 |
