1 | Page
Principles of Pharmacology APEA Questions and
Answers
The primary site of drug metabolism is the:
Ans: Liver
Which of the following NOT a plasma protein that binds to
medications?
Ans: Gamma globulins
The process by which the body breaks down and coverts a
medication into active chemical substances is known as:
Ans: Metabolism
When on drug displaces another drug from the binding sites on
proteins, causing an increase in the amount of"free" drug, this is
known as:
Ans: Distribution interactions
The pharmacodynamics of a medication would NOT be affected
by:
Ans: absorption
The process whereby a drug's activity is altered in order to
prepare it for excretion is known as:
© 2025 All rights reserved
, 2 | Page
Ans: biotransformation
In the pharmacokinetics of a drug, the rate of metabolism:
Ans: varies widely among patients
The term that describes the movement of a drug among parts of
the body is:
Ans: Distribution
The fusion of synaptic vesicles to the presynaptic plasma
membrane is preceded by the influx of:
Ans: Calcium ions
Pharmadynamic interactions that occur when two drugs act on
distinct receptors is known as:
Ans: Heterodynamic competitors
The protein-bound part of a drug is:
Ans: inactive and acts as a reservoir
To elicit an effective bioavailability response, drugs with a high
affinity for a receptor site need to be delivered:
Ans: in lower doses
The process by which cells ingest extracellular fluid and its
contents, including protein-bound medications, is known as:
Ans: pinocytosis
© 2025 All rights reserved
Principles of Pharmacology APEA Questions and
Answers
The primary site of drug metabolism is the:
Ans: Liver
Which of the following NOT a plasma protein that binds to
medications?
Ans: Gamma globulins
The process by which the body breaks down and coverts a
medication into active chemical substances is known as:
Ans: Metabolism
When on drug displaces another drug from the binding sites on
proteins, causing an increase in the amount of"free" drug, this is
known as:
Ans: Distribution interactions
The pharmacodynamics of a medication would NOT be affected
by:
Ans: absorption
The process whereby a drug's activity is altered in order to
prepare it for excretion is known as:
© 2025 All rights reserved
, 2 | Page
Ans: biotransformation
In the pharmacokinetics of a drug, the rate of metabolism:
Ans: varies widely among patients
The term that describes the movement of a drug among parts of
the body is:
Ans: Distribution
The fusion of synaptic vesicles to the presynaptic plasma
membrane is preceded by the influx of:
Ans: Calcium ions
Pharmadynamic interactions that occur when two drugs act on
distinct receptors is known as:
Ans: Heterodynamic competitors
The protein-bound part of a drug is:
Ans: inactive and acts as a reservoir
To elicit an effective bioavailability response, drugs with a high
affinity for a receptor site need to be delivered:
Ans: in lower doses
The process by which cells ingest extracellular fluid and its
contents, including protein-bound medications, is known as:
Ans: pinocytosis
© 2025 All rights reserved
