Correct) 2025/2026 |VERIFIED|
A 65-year-old female post-operative day 2 following a hip replacement presents with confusion, fever,
and hypotension. Her white blood cell count is elevated. What is the most likely cause, and what is the
initial intervention?
Post-operative infection (e.g., urinary tract infection or surgical site infection); start broad-
spectrum antibiotics and initiate cultures from appropriate sites
A 50-year-old male with a history of alcohol abuse is admitted with altered mental status, agitation, and
tremors. His vital signs are normal, but he has a history of delirium tremens. What is the most important
treatment for this patient?
Administer benzodiazepines to prevent and treat alcohol withdrawal symptoms, and monitor for
seizures or further deterioration
A 58-year-old male presents with acute chest pain, dyspnea, and tachycardia. His troponin levels are
elevated, and an ECG shows ST elevation in the anterior leads. What is the first intervention?
Administer aspirin and heparin, and prepare for immediate cardiac catheterization or
thrombolysis if appropriate
A 70-year-old male is admitted with acute respiratory distress syndrome (ARDS) following pneumonia.
He is on mechanical ventilation with a tidal volume of 6 mL/kg of ideal body weight. What is the next
step in ventilator management?
Ensure lung-protective ventilation strategies, including keeping the plateau pressure below 30 cm
H2O, and consider prone positioning to improve oxygenation
A 48-year-old female with a history of chronic hypertension presents with severe headache, blurred
vision, and chest pain. Her blood pressure is 220/120 mmHg. What is the most appropriate
management?
Initiate intravenous antihypertensive therapy (e.g., labetalol or nicardipine) and closely monitor
for signs of end-organ damage
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,A 62-year-old male with end-stage renal disease on hemodialysis presents with nausea, vomiting, and
confusion. His serum potassium is 7.5 mEq/L. What is the most critical intervention?
Administer calcium gluconate to stabilize the myocardium, followed by sodium bicarbonate,
insulin, and glucose to lower potassium levels
A 45-year-old female is post-operative day 1 following a total abdominal hysterectomy. She develops
severe abdominal pain, vomiting, and an elevated heart rate. What is the likely cause, and what should
be done next?
Intestinal obstruction or ileus; perform abdominal imaging and provide supportive care, including
nasogastric decompression and fluid resuscitation
A 60-year-old male with a history of myocardial infarction presents with signs of heart failure and a
reduced ejection fraction. His vital signs are stable, but he is showing signs of congestion. What is the
most important medication to initiate?
Start an ACE inhibitor or ARB to reduce afterload, and consider diuretics for fluid management
and symptomatic relief
A 35-year-old female with lupus nephritis develops hematuria, proteinuria, and a creatinine level of 2.1
mg/dL. What is the priority treatment for this patient?
Initiate corticosteroid therapy to suppress the immune response and consider
immunosuppressive agents like cyclophosphamide or mycophenolate
A 78-year-old male is admitted with acute-on-chronic respiratory failure due to COPD exacerbation. His
ABG shows pCO2 of 55 mmHg and pO2 of 50 mmHg. What is the most appropriate intervention?
Start non-invasive positive pressure ventilation (BiPAP) to assist ventilation and improve
oxygenation
A 53-year-old female with breast cancer presents with acute back pain, weakness, and numbness in her
lower extremities. Her MRI reveals spinal cord compression. What is the first intervention?
Administer high-dose corticosteroids to reduce spinal cord swelling and prepare for potential
surgical decompression
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,A 45-year-old male with a history of hypertension and diabetes mellitus presents with sudden loss of
vision in one eye and a headache. His blood pressure is 180/100 mmHg. What is the likely diagnosis, and
what should be done next?
Hypertensive retinopathy or optic neuropathy; lower blood pressure gradually with intravenous
antihypertensive agents and perform a fundoscopic examination
A 50-year-old female presents with decreased urine output, elevated serum creatinine, and oliguria
following major abdominal surgery. What is the most likely cause, and what should be done
immediately?
Acute kidney injury (AKI) due to hypoperfusion; initiate intravenous fluids and consider renal
replacement therapy if kidney function does not improve
A 70-year-old male with a history of cirrhosis presents with increasing ascites and abdominal distension.
He is at risk for spontaneous bacterial peritonitis. What is the first step in management?
Initiate broad-spectrum antibiotics while awaiting ascitic fluid culture results, and consider
paracentesis if necessary for diagnosis
A 25-year-old male presents to the ICU following a near-drowning event. He is hypothermic and has
labored breathing. What is the priority intervention?
Warm the patient gradually to prevent rewarming shock and initiate mechanical ventilation if
necessary for respiratory support
A 60-year-old female with a history of congestive heart failure presents with severe shortness of breath,
crackles on auscultation, and bilateral leg edema. What is the most likely cause, and what should be the
first step in treatment?
Acute decompensated heart failure; initiate diuretics to relieve fluid overload and improve
symptoms
A 30-year-old male presents with rapid onset of fever, hypotension, and petechial rash. His blood
cultures grow Neisseria meningitidis. What is the priority treatment for this patient?
Administer intravenous antibiotics (e.g., ceftriaxone) immediately and initiate fluid resuscitation
to manage septic shock
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, A 62-year-old female post-operative day 3 following a total knee replacement develops severe shortness
of breath, chest pain, and tachypnea. What is the most likely cause, and what should be done next?
Pulmonary embolism; initiate anticoagulation therapy and consider thrombolysis or surgical
intervention
A 45-year-old male with a history of hypertension and diabetes presents with altered mental status, focal
neurological deficits, and an elevated blood pressure of 200/110 mmHg. What is the most likely cause,
and what is the next step in treatment?
Acute hypertensive encephalopathy or stroke; initiate intravenous antihypertensives and perform
a CT or MRI to assess for ischemic or hemorrhagic stroke
A 58-year-old male with a history of heart failure and diabetes presents with severe shortness of breath,
hypotension, and confusion. His central venous pressure (CVP) is elevated, and his cardiac output is low.
What is the likely diagnosis?
Cardiogenic shock; initiate inotropic support, diuretics, and consider mechanical circulatory
support if necessary
A 25-year-old female presents with a headache, confusion, and weakness. Her serum sodium is 118
mEq/L, and her urine osmolality is high. What is the likely diagnosis, and what should be done
immediately?
SIADH (Syndrome of Inappropriate Antidiuretic Hormone Secretion); initiate fluid restriction and
consider hypertonic saline if needed for severe symptoms
A 30-year-old male presents to the ICU following a motor vehicle accident with a Glasgow Coma Scale
(GCS) of 8. He has a dilated, non-reactive right pupil. What is the next priority intervention?
Secure the airway and prepare for intubation to prevent further brain injury and manage
potential increased intracranial pressure
A 50-year-old female presents with severe abdominal pain, vomiting, and a rigid abdomen. Her white
blood cell count is elevated, and her blood pressure is 90/60 mmHg. What is the likely cause, and what
should be the first intervention?
Peritonitis; initiate broad-spectrum antibiotics and prepare for surgical exploration if necessary
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