LEHNE’S PHARMACOTHERAPEUTICS FOR ADVANCED
PRACTICE NURSES AND PHYSICIAN ASSISTANTS 3RD
EDITION ROSENTHAL TEST BANK
Table of Content:
UNIT I Introduction
1. Prescriptive Authority
2. Rational Drug Selection and Prescription Writing
3. Promoting Positive Outcomes of Drug Therapy
UNIT II Basic Principles of Pharmacology
4. Pharmacokinetics, Pharmacodynamics, and Drug Interactions
5. Adverse Drug Reactions and Medication Errors
6. Individual Variation in Drug Responses
7. Genetic and Genomic Considerations in Pharmacotherapeutics
UNIT III Drug Therapy Across the Life Span
8. Drug Therapy During Pregnancy and Breastfeeding
9. Drug Therapy in Pediatric Patients
10. Drug Therapy in Geriatric Patients
UNIT IV Peripheral Nervous System Drugs
11. Basic Principles of Neuropharmacology
12. Physiology of the Peripheral Nervous System
13. Muscarinic Agonists and Cholinesterase Inhibitors
14. Muscarinic Antagonists
15. Adrenergic Agonists
16. Adrenergic Antagonists
17. Indirect-Acting Antiadrenergic Agents
UNIT V Central Nervous System Drugs
18. Introduction to Central Nervous System Pharmacology
19. Drugs for Parkinson Disease
20. Drugs for Alzheimer Disease
21. Drugs for Seizure Disorders
22. Drugs for Muscle Spasm and Spasticity
UNIT VI Drugs for Pain
23. Local Anesthetics
24. Opioid Analgesics, Opioid Antagonists, and Nonopioid Centrally Acting Analgesics
25. Drugs for Headache
UNIT VII Psychotherapeutic Drugs
26. Antipsychotic Agents and Their Use in Schizophrenia
27. Antidepressants
28. Drugs for Bipolar Disorder
,29. Sedative-Hypnotic Drugs
30. Management of Anxiety Disorders
31. Central Nervous System Stimulants and Attention-Deficit/Hyperactivity Disorder
UNIT VIII Substance Use Disorders
32. Substance Use Disorders I: Basic Considerations
33. Substance Use Disorders II: Alcohol
34. Substance Use Disorders III: Nicotine and Smoking
35. Substance Use Disorders IV: Major Drugs of Misuse Other Than Alcohol and Nicotine
UNIT IX Drugs That Affect the Heart, Blood Vessels, Blood, and Blood Volume
36. Review of Hemodynamics
37. Diuretics
38. Drugs Acting on the Renin-Angiotensin-Aldosterone System
39. Calcium Channel Blockers
40. Vasodilators
41. Drugs for Hypertension
42. Drugs for Heart Failure
43. Antidysrhythmic Drugs
44. Prophylaxis of Atherosclerotic Cardiovascular Disease: Drugs That Help Normalize Cholesterol and
Triglyceride Levels
45. Drugs for Angina Pectoris
46. Anticoagulant and Antiplatelet Drugs
47. Drugs for Deficiency Anemias
UNIT X Drugs for Endocrine Disorders
48. Drugs for Diabetes
49. Drugs for Thyroid Disorders
UNIT XI Reproductive Health
50. Estrogens and Progestins: Basic Pharmacology and Noncontraceptive Applications
51. Birth Control
52. Androgens
53. Drugs for Benign Prostatic Hyperplasia
54. Drugs for Sexual Dysfunction
55. Transgender Health
UNIT XII Antiinflammatory, Antiallergic, and Immunologic Drugs
56. Review of the Immune System
57. Childhood Immunization
58. Antihistamines
59. Cyclooxygenase Inhibitors, Nonsteroidal Antiinflammatory Drugs, and Acetaminophen
60. Glucocorticoids in Nonendocrine Disorders
UNIT XIII Drugs for Bone and Joint Disorders
61. Drug Therapy for Rheumatoid Arthritis
62. Drug Therapy for Gout
63. Drugs Affecting Calcium Levels and Bone Mineralization
UNIT XIV Respiratory Tract Drugs
64. Drugs for Asthma and Chronic Obstructive Pulmonary Disease
65. Drugs for Allergic Rhinitis, Cough, and Colds
,UNIT XV Gastrointestinal Drugs
66. Drugs for Peptic Ulcer Disease
67. Laxatives
68. Other Gastrointestinal Drugs
UNIT XVI Nutrition and Complementary Therapies
69. Vitamins
70. Drugs for Obesity
71. Complementary and Alternative Therapy
UNIT XVII Therapy for Infectious and Parasitic Diseases
72. Basic Principles of Antimicrobial Therapy
73. Drugs That Weaken the Bacterial Cell Wall I: Penicillins
74. Drugs That Weaken the Bacterial Cell Wall II: Other Drugs
75. Bacteriostatic Inhibitors of Protein Synthesis
76. Aminoglycosides: Bactericidal Inhibitors of Protein Synthesis
77. Sulfonamide Antibiotics and Trimethoprim
78. Drug Therapy for Urinary Tract Infections
79. Drug Therapy for Tuberculosis
80. Miscellaneous Antibacterial Drugs
81. Antifungal Agents
82. Antiviral Agents I: Drugs for Non-HIV Viral Infections
83. Antiviral Agents II: Drugs for HIV Infection
84. Drug Therapy for Sexually Transmitted Infections
85. Anthelmintics
UNIT XVIII Cancer Therapy
86. Introduction to Immunomodulators
87. Supportive Care of Patients Receiving Anticancer Drugs
88. Drugs for Cancer Pain
UNIT XIX Drugs for Eyes, Ears, and Skin
89. Drugs for Disorders of the Eye
90. Drugs for Disorders of the Skin
91. Drugs for Disorders of the Ear
UNIT XX Drug Therapy in Acute Care
92. Agents Affecting the Volume and Ion Content of Body Fluids
93. Management of ST-Elevation Myocardial Infarction
94. Drugs for Acute Care
Appendix: Canadian Drug Information
,Chapter 1: Prescriptive Authority
Test Bank
Multiple Choice
1. An APRN works in a urology clinic under the supervision of a physician who does not restrict
the types of medications the APRN is allowed to prescribe. State law does not require the
APRN to practice under physician supervision. How would the APRN‘s prescriptive authority
be described?
a. Full authority
b. Independent
c. Without limitation
d. Limited authority
ANS: B
The APRN has independent prescriptive authority because the regulating body does not require
that the APRN work under physician supervision. Full prescriptive authority gives the provider
the right to prescribe independently and without limitation. Limited authority places restrictions
on the types of drugs that can be prescribed.DIF: Cognitive Level: ComprehensionREF: p. 1TOP:
Nursing Process: I MSC: NCLEX Client Needs Category: Physiologic Integrity: Pharmacologic
and Parenteral Therapies
2. Which factors increase the need for APRNs to have full prescriptive authority?
a. More patients will have access to health care.
b. Enrollment in medical schools is predicted to decrease.
c. Physician‘s assistants are being utilized less often.
d. APRN education is more complex than education for physicians.
ANS: A
Implementation of the Affordable Care Act has increased the number of individuals with health
care coverage, and thus the number who have access to health care services. The increase in the
number of patients creates the need for more providers with prescriptive authority. APRNs can fill
this practice gap.DIF: Cognitive Level: ComprehensionREF: p. 2TOP: Nursing Process:
Implementation MSC: NCLEX Client Needs Category: Physiologic Integrity: Pharmacologic and
Parenteral Therapies
3. Which factors could be attributed to limited prescriptive authority for APRNs?
Select all that apply.
, a. Inaccessibility of patient care
b. Higher health care costs
c. Higher quality medical treatment
d. Improved collaborative care
e. Enhanced health literacy
ANS: A , B
Limiting prescriptive authority for APRNs can create barriers to quality, affordable, and accessible
patient care. It may also lead to poor collaboration among providers and higher health care costs.
It would not directly impact patient‘s health literacy.DIF: Cognitive Level: ComprehensionREF:
p. 2TOP: Nursing Process: Implementation MSC: NCLEX Client Needs Category: Physiologic
Integrity: Pharmacologic and Parenteral Therapies
4. Which aspects support the APRN‘s provision for full prescriptive authority?
Select all that apply.
a. Clinical education includes prescription of medications and disease processes.
b. Federal regulations support the provision of full authority for APRNs.
c. National examinations provide validation of the APRN‘s ability to provide safecare.
d. Licensure ensures compliance with health care and safety standards.
e. Limiting provision can decrease health care affordability.
ANS: A , C , D
APRNs are educated to practice and prescribe independently without supervision. National
examinations validate the ability to provide safe and competent care. Licensure ensures
compliance with standards to promote public health and safety. Limited prescriptive authority
creates numerous barriers to quality, affordable, and accessible patient care.DIF: Cognitive Level:
ComprehensionREF: pp. 1-2TOP: Nursing Process: Implementation MSC: NCLEX Client Needs
Category: Physiologic Integrity: Pharmacologic and Parenteral Therapies
5. Which aspects support the APRN‘s provision for full prescriptive authority?
Select all that apply.
a. Clinical education includes prescription of medications and disease processes.
b. Federal regulations support the provision of full authority for APRNs.
c. National examinations provide validation of the APRN‘s ability to provide safecare.
d. Licensure ensures compliance with health care and safety standards.
ANS: A , C , D
APRNs are educated to practice and prescribe independently without supervision. National
examinations validate the ability to provide safe and competent care. Licensure ensures
compliance with standards to promote public health and safety. Limited prescriptive authority
creates numerous barriers to quality, affordable, and accessible patient care.DIF: Cognitive Level:
PRACTICE NURSES AND PHYSICIAN ASSISTANTS 3RD
EDITION ROSENTHAL TEST BANK
Table of Content:
UNIT I Introduction
1. Prescriptive Authority
2. Rational Drug Selection and Prescription Writing
3. Promoting Positive Outcomes of Drug Therapy
UNIT II Basic Principles of Pharmacology
4. Pharmacokinetics, Pharmacodynamics, and Drug Interactions
5. Adverse Drug Reactions and Medication Errors
6. Individual Variation in Drug Responses
7. Genetic and Genomic Considerations in Pharmacotherapeutics
UNIT III Drug Therapy Across the Life Span
8. Drug Therapy During Pregnancy and Breastfeeding
9. Drug Therapy in Pediatric Patients
10. Drug Therapy in Geriatric Patients
UNIT IV Peripheral Nervous System Drugs
11. Basic Principles of Neuropharmacology
12. Physiology of the Peripheral Nervous System
13. Muscarinic Agonists and Cholinesterase Inhibitors
14. Muscarinic Antagonists
15. Adrenergic Agonists
16. Adrenergic Antagonists
17. Indirect-Acting Antiadrenergic Agents
UNIT V Central Nervous System Drugs
18. Introduction to Central Nervous System Pharmacology
19. Drugs for Parkinson Disease
20. Drugs for Alzheimer Disease
21. Drugs for Seizure Disorders
22. Drugs for Muscle Spasm and Spasticity
UNIT VI Drugs for Pain
23. Local Anesthetics
24. Opioid Analgesics, Opioid Antagonists, and Nonopioid Centrally Acting Analgesics
25. Drugs for Headache
UNIT VII Psychotherapeutic Drugs
26. Antipsychotic Agents and Their Use in Schizophrenia
27. Antidepressants
28. Drugs for Bipolar Disorder
,29. Sedative-Hypnotic Drugs
30. Management of Anxiety Disorders
31. Central Nervous System Stimulants and Attention-Deficit/Hyperactivity Disorder
UNIT VIII Substance Use Disorders
32. Substance Use Disorders I: Basic Considerations
33. Substance Use Disorders II: Alcohol
34. Substance Use Disorders III: Nicotine and Smoking
35. Substance Use Disorders IV: Major Drugs of Misuse Other Than Alcohol and Nicotine
UNIT IX Drugs That Affect the Heart, Blood Vessels, Blood, and Blood Volume
36. Review of Hemodynamics
37. Diuretics
38. Drugs Acting on the Renin-Angiotensin-Aldosterone System
39. Calcium Channel Blockers
40. Vasodilators
41. Drugs for Hypertension
42. Drugs for Heart Failure
43. Antidysrhythmic Drugs
44. Prophylaxis of Atherosclerotic Cardiovascular Disease: Drugs That Help Normalize Cholesterol and
Triglyceride Levels
45. Drugs for Angina Pectoris
46. Anticoagulant and Antiplatelet Drugs
47. Drugs for Deficiency Anemias
UNIT X Drugs for Endocrine Disorders
48. Drugs for Diabetes
49. Drugs for Thyroid Disorders
UNIT XI Reproductive Health
50. Estrogens and Progestins: Basic Pharmacology and Noncontraceptive Applications
51. Birth Control
52. Androgens
53. Drugs for Benign Prostatic Hyperplasia
54. Drugs for Sexual Dysfunction
55. Transgender Health
UNIT XII Antiinflammatory, Antiallergic, and Immunologic Drugs
56. Review of the Immune System
57. Childhood Immunization
58. Antihistamines
59. Cyclooxygenase Inhibitors, Nonsteroidal Antiinflammatory Drugs, and Acetaminophen
60. Glucocorticoids in Nonendocrine Disorders
UNIT XIII Drugs for Bone and Joint Disorders
61. Drug Therapy for Rheumatoid Arthritis
62. Drug Therapy for Gout
63. Drugs Affecting Calcium Levels and Bone Mineralization
UNIT XIV Respiratory Tract Drugs
64. Drugs for Asthma and Chronic Obstructive Pulmonary Disease
65. Drugs for Allergic Rhinitis, Cough, and Colds
,UNIT XV Gastrointestinal Drugs
66. Drugs for Peptic Ulcer Disease
67. Laxatives
68. Other Gastrointestinal Drugs
UNIT XVI Nutrition and Complementary Therapies
69. Vitamins
70. Drugs for Obesity
71. Complementary and Alternative Therapy
UNIT XVII Therapy for Infectious and Parasitic Diseases
72. Basic Principles of Antimicrobial Therapy
73. Drugs That Weaken the Bacterial Cell Wall I: Penicillins
74. Drugs That Weaken the Bacterial Cell Wall II: Other Drugs
75. Bacteriostatic Inhibitors of Protein Synthesis
76. Aminoglycosides: Bactericidal Inhibitors of Protein Synthesis
77. Sulfonamide Antibiotics and Trimethoprim
78. Drug Therapy for Urinary Tract Infections
79. Drug Therapy for Tuberculosis
80. Miscellaneous Antibacterial Drugs
81. Antifungal Agents
82. Antiviral Agents I: Drugs for Non-HIV Viral Infections
83. Antiviral Agents II: Drugs for HIV Infection
84. Drug Therapy for Sexually Transmitted Infections
85. Anthelmintics
UNIT XVIII Cancer Therapy
86. Introduction to Immunomodulators
87. Supportive Care of Patients Receiving Anticancer Drugs
88. Drugs for Cancer Pain
UNIT XIX Drugs for Eyes, Ears, and Skin
89. Drugs for Disorders of the Eye
90. Drugs for Disorders of the Skin
91. Drugs for Disorders of the Ear
UNIT XX Drug Therapy in Acute Care
92. Agents Affecting the Volume and Ion Content of Body Fluids
93. Management of ST-Elevation Myocardial Infarction
94. Drugs for Acute Care
Appendix: Canadian Drug Information
,Chapter 1: Prescriptive Authority
Test Bank
Multiple Choice
1. An APRN works in a urology clinic under the supervision of a physician who does not restrict
the types of medications the APRN is allowed to prescribe. State law does not require the
APRN to practice under physician supervision. How would the APRN‘s prescriptive authority
be described?
a. Full authority
b. Independent
c. Without limitation
d. Limited authority
ANS: B
The APRN has independent prescriptive authority because the regulating body does not require
that the APRN work under physician supervision. Full prescriptive authority gives the provider
the right to prescribe independently and without limitation. Limited authority places restrictions
on the types of drugs that can be prescribed.DIF: Cognitive Level: ComprehensionREF: p. 1TOP:
Nursing Process: I MSC: NCLEX Client Needs Category: Physiologic Integrity: Pharmacologic
and Parenteral Therapies
2. Which factors increase the need for APRNs to have full prescriptive authority?
a. More patients will have access to health care.
b. Enrollment in medical schools is predicted to decrease.
c. Physician‘s assistants are being utilized less often.
d. APRN education is more complex than education for physicians.
ANS: A
Implementation of the Affordable Care Act has increased the number of individuals with health
care coverage, and thus the number who have access to health care services. The increase in the
number of patients creates the need for more providers with prescriptive authority. APRNs can fill
this practice gap.DIF: Cognitive Level: ComprehensionREF: p. 2TOP: Nursing Process:
Implementation MSC: NCLEX Client Needs Category: Physiologic Integrity: Pharmacologic and
Parenteral Therapies
3. Which factors could be attributed to limited prescriptive authority for APRNs?
Select all that apply.
, a. Inaccessibility of patient care
b. Higher health care costs
c. Higher quality medical treatment
d. Improved collaborative care
e. Enhanced health literacy
ANS: A , B
Limiting prescriptive authority for APRNs can create barriers to quality, affordable, and accessible
patient care. It may also lead to poor collaboration among providers and higher health care costs.
It would not directly impact patient‘s health literacy.DIF: Cognitive Level: ComprehensionREF:
p. 2TOP: Nursing Process: Implementation MSC: NCLEX Client Needs Category: Physiologic
Integrity: Pharmacologic and Parenteral Therapies
4. Which aspects support the APRN‘s provision for full prescriptive authority?
Select all that apply.
a. Clinical education includes prescription of medications and disease processes.
b. Federal regulations support the provision of full authority for APRNs.
c. National examinations provide validation of the APRN‘s ability to provide safecare.
d. Licensure ensures compliance with health care and safety standards.
e. Limiting provision can decrease health care affordability.
ANS: A , C , D
APRNs are educated to practice and prescribe independently without supervision. National
examinations validate the ability to provide safe and competent care. Licensure ensures
compliance with standards to promote public health and safety. Limited prescriptive authority
creates numerous barriers to quality, affordable, and accessible patient care.DIF: Cognitive Level:
ComprehensionREF: pp. 1-2TOP: Nursing Process: Implementation MSC: NCLEX Client Needs
Category: Physiologic Integrity: Pharmacologic and Parenteral Therapies
5. Which aspects support the APRN‘s provision for full prescriptive authority?
Select all that apply.
a. Clinical education includes prescription of medications and disease processes.
b. Federal regulations support the provision of full authority for APRNs.
c. National examinations provide validation of the APRN‘s ability to provide safecare.
d. Licensure ensures compliance with health care and safety standards.
ANS: A , C , D
APRNs are educated to practice and prescribe independently without supervision. National
examinations validate the ability to provide safe and competent care. Licensure ensures
compliance with standards to promote public health and safety. Limited prescriptive authority
creates numerous barriers to quality, affordable, and accessible patient care.DIF: Cognitive Level:
