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Btec level 3 applied medical science Unit 18 Genetics and genetic engineering Inheritance and Mendelian Genetics Assignment 3 Pass Merit distinction

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You are a geneticist working for a genetics company. You have need asked to take students on a visit around your facility. In order to do this you have been asked to complete a short assessment to ensure you are familiar with level 3 Mendelian genetics. Create a glossary of terms to demonstrate your understanding of monohybrid and dihybrid inheritance. Use a punnet square to demonstrate how two individuals who are not affected by Cystic Fibrosis can have a child who is affected by Cystic Fibrosis. Please include a full explanation with your punnet square. Use a punnet square to show the probability of an individual who is affected by Huntington’s Disease and an un-affected individual having affected children. Please include a full explanation with your punnet square. Carry out an experiment into Dihybrid Inheritance using Fruit Flies. Set up a punnet square using the following information for a dihybrid cross in fruit flies: • Dominant allele for Normal Wing = N • Recessive allele for Vestigal Wing = n • Dominant allele for Normal Body = B • Recessive allele for Ebony Body = b Cross a homozygous dominant parent with a homozygous recessive parent and explain the genotype and phenotype of the offspring in the first filial. Then use a punnet square to cross two individuals from the first filial. Explain the genotypes of the offspring in the second filial and explain the phenotypic ratios. Use the Chi Square test to analyse whether your results from the Fruit Fly experiment to support Mendelian theory. You are comparing the expected outcome predicted and your experimental data. Explain monohybrid and dihybrid ratios Apply principles of modern Mendelian genetics to predict patterns of monohybrid, dihybrid inheritance and variation Analyse the correlation between observed pattern of dihybrid inheritance and the expected pattern. My teacher gave me a Distinction for this assignment, that does not guarantee yours will but you can use my work to help you get a distinction and I hope you do :)

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Uploaded on
November 26, 2020
Number of pages
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Written in
2019/2020
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Essay
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Qualification: LV3 Extended Diploma Applied Science (Applied/Forensics/Medical)


Dihybrid Inheritance and Chi Square Analysis

In this experiment, we crossed male mutant fruit flies, which were homozygous and recessive for
both of the phenotypes with wild females that were homozygous dominant for both of the
phenotypes. The male fruit flies had an ebony body and vestigial wings, bbnn, and the females had a
normal body with normal wings, BBNN.



BN BN BN BN

bn BbNn BbNn BbNn BbNn

bn BbNn BbNn BbNn BbNn

bn BbNn BbNn BbNn BbNn

bn BbNn BbNn BbNn BbNn



BN Bn bN bn

BN BBNN BBNn BbNN BbNn

Bn BBNn BBnn BbNn Bbnn

bN BbNN BbNn bbNN bbNn

bn BbNn Bbnn bbNn bbnn



Ratio 9:3:3:1

Results

Phenotype Numbers Counted
Normal body Normal Wing 209
Normal body Vestigial wing 81
Ebony body, normal wing 90
Ebony Body Vestigial Wing 35


Alternative Hypothesis: There will be a difference between observed and expected results. Our
results did not follow the rations.

Null Hypothesis: There is no difference between observed and expected. Our results did follow the
Mendelian ratios

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