Pharmacology. Questions with |\ |\ |\
answers
When should thiazides NOT be used?
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if creatinine clearance is less than 30-50 ml/min
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True or False
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Thiazide diuretics is a first-line hypertensive agent and will also
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help to decrease fluid retention.
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True
Calcium Channel Blockers MOA |\ |\ |\
Cause coronary artery vasodilation
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Cause peripheral arterial vasodilation, thus decreasing systemic
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vascular resistance |\
Reduce the workload of the heart
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Result: decreased myocardial oxygen demand
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(Hypertension, dysrhythmias, angina, and Raynaud's) |\ |\ |\ |\
Examples of CCBs |\ |\
Verapamil, diltiazem, amlodipine, nifedipine |\ |\ |\
Indications for Verapamil |\ |\
essential HTN, angina (chronic stable, unstable), ventricular rate
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control in arrhythmia, dysrhythmias.
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gentamicin side/adverse effects |\ |\
ototoxicity, nephrotoxicity, hypersensitivity |\ |\
What classifies a diagnosis of hypertension
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, 2 elevated blood pressures at separate office visits
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One elevated BP reading does not constitute hypertension
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(White coat syndrome) |\ |\
What hypertensive medications work extremely well in the black
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and elderly white population?
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Thiazide medication. (diuretics) |\ |\
This is because these medications have been shown to decrease
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morbidity and mortality in this population. |\ |\ |\ |\ |\
For the black and elderly population, What happens to the body
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when they are on a antihypertensive for 6 months to a year?
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The body will be seeking homeostasis.
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Angiotensin II |\
increases blood pressure by stimulating kidneys to reabsorb more
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water and by releasing aldosterone
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Vasoconstrictor
What structural changes does angiotensin II do to the heart?
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Hypertrophy
Remodeling.
True or False |\ |\
Angiotensin II is NOT responsible for increasing the thickness of
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blood vessel walls. |\ |\
False