Med Surg HESI Practice Exam
Questions and Answers | Latest
Version | 2025/2026 | Correct & Verified
A patient with COPD has a PaCO₂ of 58 mmHg. Which ABG interpretation is correct?
A. Respiratory alkalosis
✔✔B. Respiratory acidosis
C. Metabolic acidosis
D. Metabolic alkalosis
A patient with chest pain is diagnosed with an acute myocardial infarction. Which medication
should be given first?
✔✔A. Aspirin
B. Atorvastatin
C. Nitroglycerin
D. Morphine
A patient with cirrhosis develops confusion and asterixis. Which laboratory value is most
important to monitor?
1
,A. Sodium
B. Potassium
✔✔C. Ammonia
D. Calcium
A patient with hypothyroidism is starting levothyroxine therapy. Which teaching is essential?
A. Take with milk to prevent stomach upset
B. Take at bedtime for better absorption
✔✔C. Take in the morning on an empty stomach
D. Take with a high-fiber breakfast
A patient with a gastric ulcer is prescribed sucralfate. What is the best time to administer this
medication?
A. After meals
✔✔B. 1 hour before meals
C. With meals
D. At bedtime only
2
,A patient with bacterial meningitis is admitted. Which type of isolation is required?
✔✔A. Droplet precautions
B. Airborne precautions
C. Contact precautions
D. Reverse isolation
A patient with hyperthyroidism has bulging eyes. What is the most important nursing
intervention?
A. Encourage more protein intake
B. Massage the eyes twice daily
✔✔C. Protect eyes from injury and dryness
D. Apply warm compresses every hour
A patient with chronic kidney disease reports muscle weakness and ECG shows peaked T waves.
Which electrolyte imbalance is most likely?
A. Hypokalemia
B. Hypernatremia
✔✔C. Hyperkalemia
3
, D. Hypocalcemia
A patient receiving IV furosemide is at risk for which complication?
✔✔A. Hypokalemia
B. Hyperkalemia
C. Hypernatremia
D. Hypercalcemia
A patient with Guillain-Barré syndrome develops shortness of breath. What is the priority action?
A. Increase IV fluids
✔✔B. Prepare for possible intubation
C. Reposition the patient
D. Administer pain medication
A patient with a DVT is receiving heparin. Which lab value is used to monitor therapeutic
effectiveness?
A. INR
✔✔B. aPTT
4
Questions and Answers | Latest
Version | 2025/2026 | Correct & Verified
A patient with COPD has a PaCO₂ of 58 mmHg. Which ABG interpretation is correct?
A. Respiratory alkalosis
✔✔B. Respiratory acidosis
C. Metabolic acidosis
D. Metabolic alkalosis
A patient with chest pain is diagnosed with an acute myocardial infarction. Which medication
should be given first?
✔✔A. Aspirin
B. Atorvastatin
C. Nitroglycerin
D. Morphine
A patient with cirrhosis develops confusion and asterixis. Which laboratory value is most
important to monitor?
1
,A. Sodium
B. Potassium
✔✔C. Ammonia
D. Calcium
A patient with hypothyroidism is starting levothyroxine therapy. Which teaching is essential?
A. Take with milk to prevent stomach upset
B. Take at bedtime for better absorption
✔✔C. Take in the morning on an empty stomach
D. Take with a high-fiber breakfast
A patient with a gastric ulcer is prescribed sucralfate. What is the best time to administer this
medication?
A. After meals
✔✔B. 1 hour before meals
C. With meals
D. At bedtime only
2
,A patient with bacterial meningitis is admitted. Which type of isolation is required?
✔✔A. Droplet precautions
B. Airborne precautions
C. Contact precautions
D. Reverse isolation
A patient with hyperthyroidism has bulging eyes. What is the most important nursing
intervention?
A. Encourage more protein intake
B. Massage the eyes twice daily
✔✔C. Protect eyes from injury and dryness
D. Apply warm compresses every hour
A patient with chronic kidney disease reports muscle weakness and ECG shows peaked T waves.
Which electrolyte imbalance is most likely?
A. Hypokalemia
B. Hypernatremia
✔✔C. Hyperkalemia
3
, D. Hypocalcemia
A patient receiving IV furosemide is at risk for which complication?
✔✔A. Hypokalemia
B. Hyperkalemia
C. Hypernatremia
D. Hypercalcemia
A patient with Guillain-Barré syndrome develops shortness of breath. What is the priority action?
A. Increase IV fluids
✔✔B. Prepare for possible intubation
C. Reposition the patient
D. Administer pain medication
A patient with a DVT is receiving heparin. Which lab value is used to monitor therapeutic
effectiveness?
A. INR
✔✔B. aPTT
4
