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CMN 548 Unit 5|COMPLETE ACCURATE QUIZZES WITH VERIFIED ANSWERS / 2025/2026

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CMN 548 Unit 5|COMPLETE ACCURATE QUIZZES WITH VERIFIED ANSWERS / 2025/2026 CMN 548 Unit 5|COMPLETE ACCURATE QUIZZES WITH VERIFIED ANSWERS / 2025/2026

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Institution
CMN 548 Unit 5
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CMN 548 Unit 5

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August 15, 2025
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Written in
2025/2026
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CMN 548 Unit 5|COMPLETE ACCURATE
QUIZZES WITH VERIFIED ANSWERS /
2025/2026

Potency - Correct answerrefers to the relative dose required to achieve certain
effects, not to the efficacy of a drug

Agonist (full agonist) - Correct answerA drug that binds to a specific receptor
producing an effect identical to that usually produced by the neurotransmitter affecting
that receptor

Pharmacodynamics - Correct answerThe time course and intensity of a drug's
effect/what the drug does to the body

Pharmacokinetics - Correct answerWhat the body does to a drug

Tolerance - Correct answerDevelops over time a need to use increased doses of
a medication/drug to maintain a clinical effect. Or, a decreased sensitivity to adverse
effects of a drug

Stevens-Johnson Syndrome - Correct answerA systemic, immune-mediated
reaction that can be fatal or result in permanent scarring or blindness

Antagonist - Correct answerA compound that blinds to a receptor that blocks or
reduces the action of another substance at the receptor site

Hyponatremia - Correct answerCommon symptoms of this medication side effect
include confusion, agitation, and lethargy. (tx with oxcarbazepine & SSRIs)

Therapeutic index - Correct answerratio of the median toxic dose to the median
effective dose

Somnolence - Correct answerDaytime sleepiness

Black Box Warning - Correct answerThis warning reflects that a medication may
cause a serious or even life-threatening side effect

,Partial or Mixed Agonist - Correct answerA compound that elicits a partial
pharmacological response at the receptor site involved

Remission - Correct answerThe degree of improvement to below the syndromal
threshold of a disorder

Paradoxical - Correct answerA response to a drug that represents the clinical
effect opposite of what is expected

Inverse agonist - Correct answerAn agent that binds to the same receptor site as
an agonist but produces the opposite pharmacological effect

4 major transmitters - Correct answerDopamine, Serotonin, GABA,
Norepinephrine

Dopamine transmitter affects? - Correct answeraffects mood, Psychosis, ADHD,
Addiction

Serotonin transmitter affects? - Correct answerDepression, aggression, OCD,
Panic, GAD, Social Anxiety, PTSD, Violence, Sexual dysfunction, substance addiction

Norepinephrine affects? - Correct answerAffects mood, anxiety, psychosis,
ADHD (part), drug withdrawal

GABA affects? - Correct answerFear, anxiety, worry

Irreversible MAOIs Types - Correct answerMAOa and MAOb

Irreversible MAOIs medications - Correct answerPhenelzine (Nardil)
isocarboxazid (Marplan)
tranylcypromine (Parnate)

A single dose of MAOIs may persist in its inhibition of MAO for how long? - Correct
answerbecause they irreversibly inactivate MAOs, the therapeutic effect of a single
dose of irreversible MAOIs may persist for as long as 2 weeks

What are the most frequent adverse effects of MAOIs? - Correct
answerorthostatic hypotension, insomnia, weight gain, edema, sexual dysfunction

Reversible MAOIs (RIMAs) medications? - Correct answerMoclobemide (Maerix)

, How long will it take to recover MAO activity after a final dose of RIMA? - Correct
answerMAO activity recovers completely 24-48 hrs after the last dose of a RIMA

MAOIs are used to treat what conditions? - Correct answerdepression
panic disorder
social phobia
bulimia nervosa
ptsd
anginal pain
atypical facial pain
migraine
adhd
idiopathic orthostatic hypotension
Depression associated with TBI

Treatment for MAOI induced orthostatic hypotension? - Correct answerAvoid
caffeine
intake of 2L of fluid/day
addition of dietary salt
adjust HTN meds
support stocking
severe cases *tx with fludrocortisone (Florinef) a mineralcorticoid

How long should the NP wait to begin another tx for depression when stopping an MAOI
to begin another MAOI or SSRI? - Correct answerirreversible MAOI-wait 14 days
MAO activity recovers completely 24-48 hrs after last dose of RIMA

How long should the NP wait to begin an MAOI after d/c a pt from fluoxetine (Prozac)? -
Correct answerwhen switching from an antidepressant to an irreversible MAOI-
should wait 10-14 days (or 5 weeks for fluoxetine (Prozac) before starting use of MAOI
to avoid drug interactions

Complications for using MAOIs for pts who have bipolar I and schizophrenia? -
Correct answerinduction of mania in the depressed phase of bipolar I disorder
and triggering of a psychotic decompensation in persons with schizophrenia

Symptoms of tyramine-induced hypertensive crisis? - Correct answerSevere
HTN
HA
Stiff neck
diaphoresis
N/V

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