1. Convert 0.25 g of amoxicillin to milligrams.
2. A prescription requires 250 mg of paracetamol every 6 hours for 7 days. Calculate the total quantity (in mg) to
supply.
3. Calculate the daily dose of gentamicin for a 70 kg patient if the dose is 5 mg/kg/day.
4. The dose of a medication is 2 mg/kg twice daily. Calculate the total dose per day for a patient weighing 55 kg.
5. Calculate the dose for a child weighing 20 kg given 10 mg/kg/day in two divided doses.
6. A drug dose is 150 mg/m². Calculate the dose for a child with a body surface area of 0.85 m².
7. Calculate the amount of active ingredient in 250 mL of a 5% w/v solution.
8. A cream contains 2% w/w of hydrocortisone. How much hydrocortisone is in 30 g of cream?
9. How much water is needed to dilute 100 mL of a 10% solution to 2%?
10. Calculate the volume of stock solution (10 mg/mL) needed to prepare 200 mL of a 2 mg/mL solution.
11. When preparing a suspension, 5 g of powder displaces 3 mL of volume. If the final volume is 100 mL, what
volume of diluent is required?
12. A suppository base displaces 0.4 mL per 1 g of drug. If 2 g of drug is added, how much base volume is displaced?
13. Calculate the drip rate (drops/min) for an infusion of 500 mL over 4 hours, with a drip factor of 20 drops/mL.
14. A patient requires an infusion of 60 mg/hour of drug solution at 2 mg/mL. Calculate the infusion rate in mL/hour.
15. A patient with renal impairment requires 50% of the normal dose of 400 mg daily. Calculate the adjusted dose.
16. If the creatinine clearance drops from 90 to 45 mL/min, by what fraction should the dose of a renally excreted
drug be reduced?
17. Calculate the number of millimoles of Na+ in 2 L of 0.9% sodium chloride solution. (NaCl molar mass = 58.5
g/mol)
18. How many millimoles of K+ are in 40 mL of 15% potassium chloride solution? (KCl molar mass = 74.5 g/mol)
19. Calculate the volume of 10% and 20% solutions needed to make 500 mL of 15% solution.
20. Mix two solutions of strengths 4 mg/mL and 10 mg/mL to make 300 mL of 7 mg/mL. Calculate volumes of each
solution required.
21. A pessary contains 100 mg of active ingredient in 3 g base. Calculate the percentage strength (% w/w).
22. If the base displaces 0.1 mL per pessary, how much base volume is required to make 50 pessaries?
23. A cocoa butter base displaces 0.2 mL per 2 g of drug added. Calculate the displacement volume if 10 g of drug is
used.
24. Calculate the weight of active ingredient in a 2 g suppository containing 1.5% w/w drug.
2. A prescription requires 250 mg of paracetamol every 6 hours for 7 days. Calculate the total quantity (in mg) to
supply.
3. Calculate the daily dose of gentamicin for a 70 kg patient if the dose is 5 mg/kg/day.
4. The dose of a medication is 2 mg/kg twice daily. Calculate the total dose per day for a patient weighing 55 kg.
5. Calculate the dose for a child weighing 20 kg given 10 mg/kg/day in two divided doses.
6. A drug dose is 150 mg/m². Calculate the dose for a child with a body surface area of 0.85 m².
7. Calculate the amount of active ingredient in 250 mL of a 5% w/v solution.
8. A cream contains 2% w/w of hydrocortisone. How much hydrocortisone is in 30 g of cream?
9. How much water is needed to dilute 100 mL of a 10% solution to 2%?
10. Calculate the volume of stock solution (10 mg/mL) needed to prepare 200 mL of a 2 mg/mL solution.
11. When preparing a suspension, 5 g of powder displaces 3 mL of volume. If the final volume is 100 mL, what
volume of diluent is required?
12. A suppository base displaces 0.4 mL per 1 g of drug. If 2 g of drug is added, how much base volume is displaced?
13. Calculate the drip rate (drops/min) for an infusion of 500 mL over 4 hours, with a drip factor of 20 drops/mL.
14. A patient requires an infusion of 60 mg/hour of drug solution at 2 mg/mL. Calculate the infusion rate in mL/hour.
15. A patient with renal impairment requires 50% of the normal dose of 400 mg daily. Calculate the adjusted dose.
16. If the creatinine clearance drops from 90 to 45 mL/min, by what fraction should the dose of a renally excreted
drug be reduced?
17. Calculate the number of millimoles of Na+ in 2 L of 0.9% sodium chloride solution. (NaCl molar mass = 58.5
g/mol)
18. How many millimoles of K+ are in 40 mL of 15% potassium chloride solution? (KCl molar mass = 74.5 g/mol)
19. Calculate the volume of 10% and 20% solutions needed to make 500 mL of 15% solution.
20. Mix two solutions of strengths 4 mg/mL and 10 mg/mL to make 300 mL of 7 mg/mL. Calculate volumes of each
solution required.
21. A pessary contains 100 mg of active ingredient in 3 g base. Calculate the percentage strength (% w/w).
22. If the base displaces 0.1 mL per pessary, how much base volume is required to make 50 pessaries?
23. A cocoa butter base displaces 0.2 mL per 2 g of drug added. Calculate the displacement volume if 10 g of drug is
used.
24. Calculate the weight of active ingredient in a 2 g suppository containing 1.5% w/w drug.
