ANCC Acute Care Nurse Practitioner (ACNP) Board Exam Review Questions and Answers | Latest Version | 2025/2026 | Correct & Verified

ANCC Acute Care Nurse Practitioner (ACNP) Board Exam Review Questions and Answers | Latest Version | 2025/2026 | Correct & Verified A 68-year-old male with COPD presents with increasing dyspnea and productive cough. Which test is most appropriate to evaluate for an acute exacerbation? A. Chest CT scan B. Chest X-ray C. Pulmonary angiogram D. Echocardiogram Which of the following electrolyte abnormalities is most likely to cause peaked T waves on an EKG? A. Hypocalcemia B. Hypomagnesemia C. Hyperkalemia D. Hyponatremia 2 A patient with suspected sepsis is hypotensive after receiving 30 mL/kg fluid resuscitation. What is the next best step in management? A. Start oral antibiotics B. Initiate vasopressors C. Order repeat urinalysis D. Wait for blood culture results Which of the following antibiotics is most appropriate for initial empiric therapy in hospital- acquired pneumonia? A. Amoxicillin B. Piperacillin-tazobactam C. Azithromycin D. Cephalexin In a patient with a deep vein thrombosis (DVT), which of the following findings supports the diagnosis of a pulmonary embolism? A. Sudden-onset dyspnea and pleuritic chest pain B. Gradual-onset abdominal pain C. Bradycardia and hypothermia 3 D. Productive cough with green sputum Which of the following is a common side effect of amiodarone? A. Pulmonary fibrosis B. Hypertension C. Hypoglycemia D. Liver failure within 24 hours A patient with heart failure has an ejection fraction of 25%. Which medication improves survival? A. Furosemide B. Lisinopril C. Digoxin D. Acetaminophen A 45-year-old female presents with confusion, fever, and a stiff neck. What is the most appropriate initial diagnostic test? A. Lumbar puncture 4 B. CT of the chest C. EEG D. Liver ultrasound Which of the following is the most appropriate intervention in a patient with status epilepticus not responding to lorazepam? A. Repeat lorazepam