ANCC Sample Test Questions –
PMHNP Questions and Answers |
Latest Version | 2025/2026 | Correct &
Verified
A patient presents with symptoms of persistent sadness, anhedonia, and sleep disturbances for 6
months. What is the most likely diagnosis?
A. Adjustment disorder
✔✔B. Major depressive disorder
C. Acute stress disorder
D. Cyclothymia
Which medication class is most appropriate as a first-line treatment for generalized anxiety
disorder?
A. Antipsychotics
B. Benzodiazepines
✔✔C. SSRIs
D. MAOIs
1
,A 23-year-old reports hearing voices telling him he is worthless. What is the best initial
intervention?
✔✔A. Conduct a suicide risk assessment immediately
B. Refer to counseling in one week
C. Prescribe a sleep aid
D. Recommend group therapy
Which lab value should be monitored regularly in a patient taking valproic acid?
✔✔A. Liver function tests
B. BUN
C. Blood glucose
D. Creatinine
What is the best response when a patient with borderline personality disorder says, “You’re the
only one who understands me. The others are useless”?
A. “I agree, they don’t get it.”
✔✔B. “Let’s focus on how that made you feel.”
C. “You should tell them that directly.”
2
, D. “Ignore them and listen to me instead.”
What is the black box warning on all antidepressants for children and adolescents?
A. Cardiac toxicity
✔✔B. Increased risk of suicidal ideation
C. Liver failure
D. Weight gain
Which therapeutic technique is most aligned with motivational interviewing?
✔✔A. Expressing empathy and supporting self-efficacy
B. Giving direct advice and orders
C. Correcting distorted thinking
D. Analyzing unconscious drives
A PMHNP is working with a patient diagnosed with schizophrenia. What is the primary target
symptom for antipsychotic medication?
A. Insomnia
✔✔B. Hallucinations
3
PMHNP Questions and Answers |
Latest Version | 2025/2026 | Correct &
Verified
A patient presents with symptoms of persistent sadness, anhedonia, and sleep disturbances for 6
months. What is the most likely diagnosis?
A. Adjustment disorder
✔✔B. Major depressive disorder
C. Acute stress disorder
D. Cyclothymia
Which medication class is most appropriate as a first-line treatment for generalized anxiety
disorder?
A. Antipsychotics
B. Benzodiazepines
✔✔C. SSRIs
D. MAOIs
1
,A 23-year-old reports hearing voices telling him he is worthless. What is the best initial
intervention?
✔✔A. Conduct a suicide risk assessment immediately
B. Refer to counseling in one week
C. Prescribe a sleep aid
D. Recommend group therapy
Which lab value should be monitored regularly in a patient taking valproic acid?
✔✔A. Liver function tests
B. BUN
C. Blood glucose
D. Creatinine
What is the best response when a patient with borderline personality disorder says, “You’re the
only one who understands me. The others are useless”?
A. “I agree, they don’t get it.”
✔✔B. “Let’s focus on how that made you feel.”
C. “You should tell them that directly.”
2
, D. “Ignore them and listen to me instead.”
What is the black box warning on all antidepressants for children and adolescents?
A. Cardiac toxicity
✔✔B. Increased risk of suicidal ideation
C. Liver failure
D. Weight gain
Which therapeutic technique is most aligned with motivational interviewing?
✔✔A. Expressing empathy and supporting self-efficacy
B. Giving direct advice and orders
C. Correcting distorted thinking
D. Analyzing unconscious drives
A PMHNP is working with a patient diagnosed with schizophrenia. What is the primary target
symptom for antipsychotic medication?
A. Insomnia
✔✔B. Hallucinations
3
