COMSAE 105B EXAM QUESTIONS AND
ANSWERS|REVISION|
DMARD drug for UC/Crohns/RA - ✔✔sulfasalazine
pulmonary effects of CF - ✔✔chronic bronchitis and bronchiectasis
osteoporosis affects what parts of bone? - ✔✔(spongy and ) trabecular bone mass loss
imipramine - ✔✔TCA
SE: Tri-Cs
convulsions
coma
cardiotox
antichol effects- confusion in elderly; (acute glaucoma and orthostatic hypotension- block
alpha1)
viscerosomatic - ✔✔visceral disease --> somatic finding
loratidine vs ranitidine - ✔✔loratidine: 2nd gen H1 blocker, doesnt cross BBB --> less sedating
ranitidine: H2 receptor antagonist (like cimetidine)
cells w RBCs inside - ✔✔entaemoba histolytica
which type of pneumothorax causes tracheal deviation to the contra side? - ✔✔tension
,intracerebral hemorrhage adjacent to a lesion that contains a tangle of numerous tortuous vessels
- ✔✔AVM arteriovenous malformation
cavernous hemangioma - ✔✔benign tumor of liver, A/W VHL
anti-HepB surface antibody is only present in what pop - ✔✔recovered or immunized
not in chronic or
proctalgia fugax - ✔✔levator ani syndrome
fasciculus is UMN or LMN lesion? - ✔✔LMN
ectopic gastric tissue - ✔✔meckels diverticulum
can also have ectopic pancreatic tissue
remnant of vitelline duct
antibodies in hashimotos attacks - ✔✔thyroid peroxidase or antithyroglobulin
enlarged non tender thyroid
2 factors that influence starling curve - ✔✔x axis- preload (EDV)
y axis- stroke volume or CO
treatment for fibromyalgia - ✔✔TCA, SNRIs anticonvulsants
,what blocks NE reuptake? - ✔✔TCA or SNRIs
possible complication of pagets bone disease - ✔✔osteocarcoma
what does Hct tell you? - ✔✔ratio of volume of RBCs compared to total blood volume
probenecid - ✔✔inhibits reabsoprtion of uric acid in PCT
- also inhibits secretion of PCN
- can ppt uric acid calculi
2 causes of SCID - ✔✔ADA deficiency
(adenosine deaminase required for degradation of adenosim and deoxyadenosine
- in ADA deficiency, high levels of dATP --> toxicity in lymphocytes --> SCID
hypoplastic thymus
lithiums effects on urination - ✔✔inhibits vasopression/ADH --> increased urinary frequency
infertility drug that can result in multiple fetuses - ✔✔clomiphene (clones- multiple babies)
antagonist at estrogen R in hypothalamus (thus inhibits normal negative feedback)
upregulates LH and FSH release from pituitary --> ovulation
used to treat PCOS but can cause ovarian enlargement, multiple fetuses
, AFP levels in down syndrome - ✔✔low
GI malformation A/W down syndrome - ✔✔Hirschprungs- congenital aganglionic megacolon
defective relaxation and peristalsis of rectum and distal sigmoid colon
failure to pass meconium, empty rectal vault, megacolon
myasthenia gravis associations - ✔✔thymoma, thymic hyperplasia
ptosis, diplopia, can affect chewing, swallowing, speaking, shoulders, respiration
tx for tinea - ✔✔azoles
beta blockers for asthma - ✔✔none- even beta 1s can be nonselective at higher doses
what kind of teratogenic effects are seen w ACE/ARBs - ✔✔fetal renal agenesis
stones bones groans moans psych overtones - ✔✔high Ca or PTH
PTH is made by what cells? - ✔✔chief cells of parathyroid gland
PTH inhibits reabsorption of phosphate where? increases calcium resorption where? - ✔✔PO4-
proximal tubule
ca- DCT
anterior innominate rotation means tight hip flexors or extensors? - ✔✔extensor- hamstrings
ANSWERS|REVISION|
DMARD drug for UC/Crohns/RA - ✔✔sulfasalazine
pulmonary effects of CF - ✔✔chronic bronchitis and bronchiectasis
osteoporosis affects what parts of bone? - ✔✔(spongy and ) trabecular bone mass loss
imipramine - ✔✔TCA
SE: Tri-Cs
convulsions
coma
cardiotox
antichol effects- confusion in elderly; (acute glaucoma and orthostatic hypotension- block
alpha1)
viscerosomatic - ✔✔visceral disease --> somatic finding
loratidine vs ranitidine - ✔✔loratidine: 2nd gen H1 blocker, doesnt cross BBB --> less sedating
ranitidine: H2 receptor antagonist (like cimetidine)
cells w RBCs inside - ✔✔entaemoba histolytica
which type of pneumothorax causes tracheal deviation to the contra side? - ✔✔tension
,intracerebral hemorrhage adjacent to a lesion that contains a tangle of numerous tortuous vessels
- ✔✔AVM arteriovenous malformation
cavernous hemangioma - ✔✔benign tumor of liver, A/W VHL
anti-HepB surface antibody is only present in what pop - ✔✔recovered or immunized
not in chronic or
proctalgia fugax - ✔✔levator ani syndrome
fasciculus is UMN or LMN lesion? - ✔✔LMN
ectopic gastric tissue - ✔✔meckels diverticulum
can also have ectopic pancreatic tissue
remnant of vitelline duct
antibodies in hashimotos attacks - ✔✔thyroid peroxidase or antithyroglobulin
enlarged non tender thyroid
2 factors that influence starling curve - ✔✔x axis- preload (EDV)
y axis- stroke volume or CO
treatment for fibromyalgia - ✔✔TCA, SNRIs anticonvulsants
,what blocks NE reuptake? - ✔✔TCA or SNRIs
possible complication of pagets bone disease - ✔✔osteocarcoma
what does Hct tell you? - ✔✔ratio of volume of RBCs compared to total blood volume
probenecid - ✔✔inhibits reabsoprtion of uric acid in PCT
- also inhibits secretion of PCN
- can ppt uric acid calculi
2 causes of SCID - ✔✔ADA deficiency
(adenosine deaminase required for degradation of adenosim and deoxyadenosine
- in ADA deficiency, high levels of dATP --> toxicity in lymphocytes --> SCID
hypoplastic thymus
lithiums effects on urination - ✔✔inhibits vasopression/ADH --> increased urinary frequency
infertility drug that can result in multiple fetuses - ✔✔clomiphene (clones- multiple babies)
antagonist at estrogen R in hypothalamus (thus inhibits normal negative feedback)
upregulates LH and FSH release from pituitary --> ovulation
used to treat PCOS but can cause ovarian enlargement, multiple fetuses
, AFP levels in down syndrome - ✔✔low
GI malformation A/W down syndrome - ✔✔Hirschprungs- congenital aganglionic megacolon
defective relaxation and peristalsis of rectum and distal sigmoid colon
failure to pass meconium, empty rectal vault, megacolon
myasthenia gravis associations - ✔✔thymoma, thymic hyperplasia
ptosis, diplopia, can affect chewing, swallowing, speaking, shoulders, respiration
tx for tinea - ✔✔azoles
beta blockers for asthma - ✔✔none- even beta 1s can be nonselective at higher doses
what kind of teratogenic effects are seen w ACE/ARBs - ✔✔fetal renal agenesis
stones bones groans moans psych overtones - ✔✔high Ca or PTH
PTH is made by what cells? - ✔✔chief cells of parathyroid gland
PTH inhibits reabsorption of phosphate where? increases calcium resorption where? - ✔✔PO4-
proximal tubule
ca- DCT
anterior innominate rotation means tight hip flexors or extensors? - ✔✔extensor- hamstrings
