NCMP – Pharmacology Exam 2 (Parts 6 & 18) – Comprehensive Review with Accurate Answers

NCMP Pharm Exam 2 (Pt. 6, 18) questions with
accurate answers
1. Chlorpromazine (Thorazine)
2. Haloperidol (Haldol)
3. Prochlorperazine (Compazine) Ans✓✓✓ Typical antipsychotics
examples (3)


1. Clozapine (Clozaril)
2. Risperidone (Risperdal)
3. Olanzapine (Zyprexa)
4. Quetiapine (Seroquel) Ans✓✓✓ Atypical antipsychotics examples
(4)


1. CNS excitation
2. Incr. BP Ans✓✓✓ MAO inhibitors - adverse effects (2)


1. Drug inhibits cholinesterase enzyme
2. ACh breakdown is inhibited
3. ACh activity/effects prolonged Ans✓✓✓ Indirect cholinergic
stimulants - effects in dementia (3)


1. Drugs incr. activity of amine NTs
2. Incr. NT activity incr. brain-derived neurotrophic factor (BDNF)

, 3. BDNF stimulates growth (neurogenesis) in hippocampus Ans✓✓✓
Why might incr. amine NTs decr. depression? (3)


1. GI irritation
2. Hypotension
3. Psychotropic, behavioral effects
4. Dyskinesias
5. Freezing of gait Ans✓✓✓ Side effects of L-dopa therapy (5)


1. Incr. dopamine content in basal ganglia
2. Direct administration of dopamine ineffective bc of BBB
3. Must provide precursor to dopamine - levodopa (L-DOPA) Ans✓✓✓
Rationale for levodopa therapy (3)


1. Incr. seizures
2. GI problems Ans✓✓✓ SSRIs/SNRIs adverse effects (2)


1. inhibiting reuptake of 1+ amine neurotransmitters
2. decr. neurotransmitter breakdown (MAO inhibitors) Ans✓✓✓
Antidepressants prolong effects of amine neurotransmitter by... (2)


1. Paroxetine (Paxil)
2. Venlafaxine (Effexor)
3. Duloxetine (Cymbalta)