celiac disease Exam Questions And
Verified Answers | Grade A+ | 100%
Correct!!!!
other names for celiac disease CORRECT ANSWERS Sprue
Non Tropical Sprue
Celiac Sprue
Gluten Sensitive Enteropathy
Spectrum of celiac disorders CORRECT ANSWERS Celiac Disease
Celiac Disease Negative Gluten Sensitivity
-'Gluten Intolerance'
Refractory Celiac Disease
Ulcerative Jejunoileitis
Small Bowel Lymphoma, adenocarcinoma
Definition of celiac disease CORRECT ANSWERS An autoimmune disease
characterized by chronic intestinal inflammation and varying degrees of intestinal
mucosal atrophy with associated malabsorption.
Or
An antigen driven enteropathy of the small intestine, resulting from an inappropriate
immune response to dietary gliadin, a component of wheat proteins.
Facts about celiac disease CORRECT ANSWERS -reaction to a non-digestible protein
in wheat called gluten
-*not an allergy*
-autoimmune disorder
-lifelong
- treatable with diet changes
Presentation of celiac disease CORRECT ANSWERS *Widely variable presentation *
-from severe steatorrhea, distension and weight loss or failure to thrive to cramping and
abdominal pain.
-tympanitis doughy abdomen on exam
-Some asymptomatic
-*Microcytic anemia / iron deficiency without GI blood loss*
-can present in children or adults
Celiac disease severity CORRECT ANSWERS Depends on the length of bowel affected
-*changes begin in the duodenum and extend distally*
-the proximal bowel is more affected
severe celiac disease CORRECT ANSWERS -megaloblastic anemia
, -neurologic disease (B12)
-Infertility
-Amenorrhea
-Osteoporosis
-Hypovitaminosis D
mild celiac disease CORRECT ANSWERS Mild iron deficiency anemia
Iron and folate deficiency
Silent celiac disease CORRECT ANSWERS Asymptomatic, but
*-Positive serology
-Abnormal biopsy*
Latent celiac disease CORRECT ANSWERS Positive serology only
-no abnormalities on biopsy
GI manifestations of celiac disease CORRECT ANSWERS -Diarrhea / Steatorrhea -
increased osmotic load, bile malabsorption in ileum, poor motility, colon bacterial action
(hydroxy fatty acids)
-Flatulence
-Weight loss
-Distension, cramping
Extra intestinal manifestations of celiac disease CORRECT ANSWERS -*Anemia* -
(iron, folate, B12)
-*Osteogenic bone disease* (Ca, low vitamin D)
-*Muscle cramps, tetany *(Low Ca++, Mg++)
-*Bleeding *(vitamin K)
-*Peripheral neuropathy*
-Menstrual abnormalities, *infertility.*
Appearance of celiac disease on endoscopy CORRECT ANSWERS Flattening of the
circular folds as well as scalloping along the edges
Gold standard for diagnosis of celiac disease CORRECT ANSWERS -Small bowel
biopsy from the duodenum or upper jejunum
-classic findings are:
* villi atrophy
crypt hyperplasia
increased intraepithelial lymphocytes*
mucosal inflammation
Differential diagnosis of celiac disease CORRECT ANSWERS -Infectious
gastroenteritis/bacterial overgrowth
-tropical sprue
Verified Answers | Grade A+ | 100%
Correct!!!!
other names for celiac disease CORRECT ANSWERS Sprue
Non Tropical Sprue
Celiac Sprue
Gluten Sensitive Enteropathy
Spectrum of celiac disorders CORRECT ANSWERS Celiac Disease
Celiac Disease Negative Gluten Sensitivity
-'Gluten Intolerance'
Refractory Celiac Disease
Ulcerative Jejunoileitis
Small Bowel Lymphoma, adenocarcinoma
Definition of celiac disease CORRECT ANSWERS An autoimmune disease
characterized by chronic intestinal inflammation and varying degrees of intestinal
mucosal atrophy with associated malabsorption.
Or
An antigen driven enteropathy of the small intestine, resulting from an inappropriate
immune response to dietary gliadin, a component of wheat proteins.
Facts about celiac disease CORRECT ANSWERS -reaction to a non-digestible protein
in wheat called gluten
-*not an allergy*
-autoimmune disorder
-lifelong
- treatable with diet changes
Presentation of celiac disease CORRECT ANSWERS *Widely variable presentation *
-from severe steatorrhea, distension and weight loss or failure to thrive to cramping and
abdominal pain.
-tympanitis doughy abdomen on exam
-Some asymptomatic
-*Microcytic anemia / iron deficiency without GI blood loss*
-can present in children or adults
Celiac disease severity CORRECT ANSWERS Depends on the length of bowel affected
-*changes begin in the duodenum and extend distally*
-the proximal bowel is more affected
severe celiac disease CORRECT ANSWERS -megaloblastic anemia
, -neurologic disease (B12)
-Infertility
-Amenorrhea
-Osteoporosis
-Hypovitaminosis D
mild celiac disease CORRECT ANSWERS Mild iron deficiency anemia
Iron and folate deficiency
Silent celiac disease CORRECT ANSWERS Asymptomatic, but
*-Positive serology
-Abnormal biopsy*
Latent celiac disease CORRECT ANSWERS Positive serology only
-no abnormalities on biopsy
GI manifestations of celiac disease CORRECT ANSWERS -Diarrhea / Steatorrhea -
increased osmotic load, bile malabsorption in ileum, poor motility, colon bacterial action
(hydroxy fatty acids)
-Flatulence
-Weight loss
-Distension, cramping
Extra intestinal manifestations of celiac disease CORRECT ANSWERS -*Anemia* -
(iron, folate, B12)
-*Osteogenic bone disease* (Ca, low vitamin D)
-*Muscle cramps, tetany *(Low Ca++, Mg++)
-*Bleeding *(vitamin K)
-*Peripheral neuropathy*
-Menstrual abnormalities, *infertility.*
Appearance of celiac disease on endoscopy CORRECT ANSWERS Flattening of the
circular folds as well as scalloping along the edges
Gold standard for diagnosis of celiac disease CORRECT ANSWERS -Small bowel
biopsy from the duodenum or upper jejunum
-classic findings are:
* villi atrophy
crypt hyperplasia
increased intraepithelial lymphocytes*
mucosal inflammation
Differential diagnosis of celiac disease CORRECT ANSWERS -Infectious
gastroenteritis/bacterial overgrowth
-tropical sprue
