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NCLEX-RN 2025 Practice Questions
| 400 High-Yield Qs with Rationales |
NGN-Style + Traditional Test Bank
, 2
Question 1
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A nurse is caring for a client with heart failure who is receiving furosemide. Which finding
requires immediate follow-up?
A. Serum potassium level of 3.1 mEq/L
B. Blood pressure of 132/78 mmHg
C. Reports of muscle cramps
D. Weight loss of 1.5 lbs in 24 hours
✔ Correct Answer: A
Rationale: Hypokalemia is a known side effect of loop diuretics like furosemide. A
potassium level of 3.1 is dangerously low and can lead to arrhythmias. Immediate correction
is needed.
Question 2
A nurse prepares to administer a blood transfusion. What is the nurse's priority action before
initiating the transfusion?
A. Prime the IV tubing with normal saline
B. Educate the client about signs of a transfusion reaction
C. Verify the client’s ID with the blood product label
D. Check the client’s vital signs
✔ Correct Answer: C
Rationale: The highest priority is to ensure patient safety by confirming the correct patient
and the correct blood product to prevent a life-threatening transfusion reaction.
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Question 3
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A nurse prepares to administer furosemide IV push to a client with heart failure. Which
electrolyte imbalance should the nurse monitor closely?
A. Hypercalcemia
B. Hypernatremia
C. Hypokalemia
D. Hypophosphatemia
✔ Correct Answer: C
Rationale: Furosemide is a loop diuretic that increases urinary excretion of potassium,
risking hypokalemia. Monitor K+ levels to prevent cardiac dysrhythmias.
Question 4
Which client should the nurse assess first?
A. A client with stable angina requesting pain medication
B. A client who had a colonoscopy 2 hours ago and is passing gas
C. A client with a potassium level of 2.9 mEq/L
D. A client post-hip surgery asking to use the bathroom
✔ Correct Answer: C
Rationale: Hypokalemia can lead to life-threatening cardiac dysrhythmias. This is the
priority over pain or routine post-procedural care.
Question 5
A nurse is reinforcing teaching about isoniazid (INH) to a client with TB. Which statement
, 4
indicates the need for further teaching?
A. "I will take this medication on an empty stomach."
B. "I should report any numbness or tingling in my hands or feet."
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C. "I will avoid drinking alcohol while on this drug."
D. "I can stop the medication once I feel better."
✔ Correct Answer: D
Rationale: Clients must complete the entire course of isoniazid therapy to ensure full
eradication of tuberculosis. Stopping the medication early can lead to treatment failure, drug
resistance, and prolonged infectiousness. This statement reflects a lack of understanding and
requires further education.
Question 6
A nurse is reviewing lab results for a client on warfarin therapy. Which finding requires
immediate action?
A. INR of 2.2
B. Hemoglobin of 13.0 g/dL
C. Platelet count of 150,000/mm³
D. INR of 5.5
✔ Correct Answer: D
Rationale: An INR of 5.5 indicates a dangerously high risk of bleeding. The therapeutic
range is typically 2.0–3.0 for most indications. Immediate action such as withholding
warfarin or administering vitamin K may be needed.
Page | 1
NCLEX-RN 2025 Practice Questions
| 400 High-Yield Qs with Rationales |
NGN-Style + Traditional Test Bank
, 2
Question 1
Page | 2
A nurse is caring for a client with heart failure who is receiving furosemide. Which finding
requires immediate follow-up?
A. Serum potassium level of 3.1 mEq/L
B. Blood pressure of 132/78 mmHg
C. Reports of muscle cramps
D. Weight loss of 1.5 lbs in 24 hours
✔ Correct Answer: A
Rationale: Hypokalemia is a known side effect of loop diuretics like furosemide. A
potassium level of 3.1 is dangerously low and can lead to arrhythmias. Immediate correction
is needed.
Question 2
A nurse prepares to administer a blood transfusion. What is the nurse's priority action before
initiating the transfusion?
A. Prime the IV tubing with normal saline
B. Educate the client about signs of a transfusion reaction
C. Verify the client’s ID with the blood product label
D. Check the client’s vital signs
✔ Correct Answer: C
Rationale: The highest priority is to ensure patient safety by confirming the correct patient
and the correct blood product to prevent a life-threatening transfusion reaction.
, 3
Question 3
Page | 3
A nurse prepares to administer furosemide IV push to a client with heart failure. Which
electrolyte imbalance should the nurse monitor closely?
A. Hypercalcemia
B. Hypernatremia
C. Hypokalemia
D. Hypophosphatemia
✔ Correct Answer: C
Rationale: Furosemide is a loop diuretic that increases urinary excretion of potassium,
risking hypokalemia. Monitor K+ levels to prevent cardiac dysrhythmias.
Question 4
Which client should the nurse assess first?
A. A client with stable angina requesting pain medication
B. A client who had a colonoscopy 2 hours ago and is passing gas
C. A client with a potassium level of 2.9 mEq/L
D. A client post-hip surgery asking to use the bathroom
✔ Correct Answer: C
Rationale: Hypokalemia can lead to life-threatening cardiac dysrhythmias. This is the
priority over pain or routine post-procedural care.
Question 5
A nurse is reinforcing teaching about isoniazid (INH) to a client with TB. Which statement
, 4
indicates the need for further teaching?
A. "I will take this medication on an empty stomach."
B. "I should report any numbness or tingling in my hands or feet."
Page | 4
C. "I will avoid drinking alcohol while on this drug."
D. "I can stop the medication once I feel better."
✔ Correct Answer: D
Rationale: Clients must complete the entire course of isoniazid therapy to ensure full
eradication of tuberculosis. Stopping the medication early can lead to treatment failure, drug
resistance, and prolonged infectiousness. This statement reflects a lack of understanding and
requires further education.
Question 6
A nurse is reviewing lab results for a client on warfarin therapy. Which finding requires
immediate action?
A. INR of 2.2
B. Hemoglobin of 13.0 g/dL
C. Platelet count of 150,000/mm³
D. INR of 5.5
✔ Correct Answer: D
Rationale: An INR of 5.5 indicates a dangerously high risk of bleeding. The therapeutic
range is typically 2.0–3.0 for most indications. Immediate action such as withholding
warfarin or administering vitamin K may be needed.
