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A-level Edexcel Biology, Topic 1 condensed notes

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Condensed notes for A-level Edexcel Biology Topic 1 - Lifestyle, health and risk. Notes have clear colour coordinated headings and subheadings for each topic, including diagrams and visual representations. Written by an ex-student, these notes alone allowed me to gain an A* - everything you need to know. Including common question answers.

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1.​ Lifestyle, health and risk
1.a The Circulatory System
Mass transport
Definition
●​ The bulk movement of gases or liquids through a system of vessels
Features
●​ Transport medium
●​ Network of vessels
●​ Controlled direction (valves)
●​ Maintenance of speed
Benefits
●​ Transportation of substances
●​ Maintains concentration gradient
●​ Ensures cell activity



Water
●​ Water is a polar molecule, due to an uneven distribution of charge within the
molecule - the hydrogen atoms are positive and the oxygen charges are negative,
causing one end of the molecule to be more positive than the other
●​ Due to its polarity, water acts as a solvent so can be used to transport many
biological molecules
●​ Hydrogen bonding between water molecules creates cohesion and adhesion - this
creates effective transport of water and dissolved substances through xylem vessels
●​ Hydrogen bonding is strong, causing water to have a high specific heat capacity
meaning that a lot of energy is required to break these bonds giving water a stable
temperature



Blood vessels
1.​ Arteries
●​ Most carry oxygenated blood to body tissues and deoxygenated blood to
lungs
●​ Narrow lumen to maintain high blood
pressure
●​ Smooth inner endothelial lining
●​ Thick layer of smooth muscle to dilate and
constrict vessels
●​ Elastin fibres to stretch and recoil vessel
●​ Collagen fibres to support vessel

, 1.​ Lifestyle, health and risk
2.​ Veins
●​ Most carry deoxygenated blood to lungs and oxygenated blood to heart
●​ Large lumen to reduce resistance of blood
flow
●​ Thinner layer of smooth muscle and elastin
fibres
●​ Less collagen fibres
●​ Valves to control direction of blood flow
3.​ Capillaries
●​ Smallest blood vessel
●​ Branch between cells and tissues
●​ Narrow lumen
●​ Thin endothelial wall (one cell
thick) to maintain short diffusion
distance
●​ No smooth muscle, collagen fibres or elastin fibres



Structure of the heart




The cardiac cycle
1.​ Atrial systole
●​ Ventricles are relaxed
●​ The atria contract, decreasing volume of chambers and increasing pressure
●​ This pushes blood into ventricles
●​ Causes slight increase in ventricular pressure and chamber volume

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June 25, 2025
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Topic. 1 complete - paper 1
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