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Summary BIO 141 – Central and Peripheral Nervous System (Unit 4) – Study Guide – Complete Overview of Chapters 12 and 13

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This document is a detailed study guide for Unit 4 of the BIO 141 course, covering Chapters 12 and 13 on the Central Nervous System (CNS) and Peripheral Nervous System (PNS). It includes clearly structured questions and answers related to brain anatomy, spinal cord structure, sensory and motor pathways, cranial and spinal nerves, protective structures, reflex arcs, and associated disorders. Ideal for exam preparation, this guide provides a comprehensive overview of the functional and structural components of the human nervous system.

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Human Anatomy & Physiology I
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Human Anatomy & Physiology I









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Human Anatomy & Physiology I
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Human Anatomy & Physiology I

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12 and 13
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BIO 141 Unit 4 Study Guide

Chapter 12: The Central Nervous System

1.​ What are the major areas of the brain and their functions?
●​ Cerebrum: higher functions; Diencephalon: homeostasis, relays info; Brainstem:
basic life functions; Cerebellum: coordination.
2.​ From which embryonic structure does nervous tissue develop?
●​ Neural tube.
3.​ What are the three primary brain vesicles present at four weeks gestation?
●​ Prosencephalon, mesencephalon, rhombencephalon.
4.​ Which brain regions develop from each secondary brain vesicle?
●​ Telencephalon and diencephalon from prosencephalon; mesencephalon remains;
metencephalon and myelencephalon from rhombencephalon.
5.​ How do gray matter and white matter dif+fer in composition and distribution?
●​ Gray matter: neuron cell bodies, outer cortex and basal nuclei; White matter:
myelinated axons, inner areas.
6.​ Can you identify and describe the function of sulci, gyri, lobes, and fissures?
●​ Sulci: grooves (central, parieto-occipital); Gyri: ridges (precentral = motor,
postcentral = sensory); Lobes: frontal (motor, decision), parietal (sensory),
occipital (vision), temporal (hearing), insula (taste, emotion); Fissures:
longitudinal (hemisphere divide), lateral (temporal lobe).
7.​ What are the key anatomical structures of the cerebrum and their functions?
●​ Gray matter: cerebral cortex (conscious thought), basal nuclei (movement); White
matter: corpus callosum (connect hemispheres), fornix (limbic), association (same
side), commissural (between hemispheres), projection (cortex to lower).
8.​ In which cerebral lobe is each of the following areas located?
●​ Primary motor: frontal; Broca’s: frontal; Auditory: temporal; Visual: occipital;
Somatosensory: parietal.
9.​ What are the functions of various cerebral cortical areas?
●​ Primary motor: voluntary movement; Premotor: learned movement; Broca's:
speech production; Wernicke's: speech understanding; Auditory cortex: hearing;
Visual cortex: vision; Somatosensory cortex: touch; Olfactory: smell; Gustatory:
taste; Vestibular: balance.
10.​What is the function of the limbic system?
●​ Emotion, memory.
11.​What is the function of the hippocampus?
●​ Memory formation.
12.​Can you identify and explain the functions of structures in the diencephalon?
●​ Thalamus: relay station; Hypothalamus: homeostasis, controls pituitary;
Mammillary bodies: memory; Pineal gland: melatonin.
13.​Where is the cerebellum located and what are its functions?
●​ Coordination, balance.
14.​What are folia and arbor vitae in the cerebellum?

, ●​ Folia: cerebellar folds; Arbor vitae: white matter tree.
15.​What is the function of cerebellar peduncles?
●​ Connect cerebellum to brainstem.
16.​What are the three regions of the brainstem?
●​ Midbrain, pons, medulla oblongata.
17.​Can you identify structures associated with the brainstem on an image?
●​ Midbrain, pons, medulla oblongata.
18.​What are the functions of specific brainstem structures?
●​ Substantia nigra: dopamine, movement; Medulla: autonomic control; Pons:
bridge; Colliculi: visual/auditory reflexes; Pyramids: motor tracts.
19.​What is the function of the reticular activating system (RAS)?
●​ Consciousness and alertness.
20.​What is cerebral lateralization and how do hemispheres differ?
●​ Left = logic/language, Right = emotion/art.
21.​What brain changes occur in Alzheimer’s disease?
●​ Neurofibrillary tangles, amyloid plaques, brain shrinkage.
22.​What structures protect the brain?
●​ Skull, meninges, CSF, blood-brain barrier.
23.​What are the meninges and their locations?
●​ Dura (outer), arachnoid (middle), pia (inner).
24.​Where are the subarachnoid, subdural, and epidural spaces?
●​ Subarachnoid (CSF), subdural (potential), epidural (fat).
25.​What is the function of dural venous sinuses?
●​ Venous blood drainage.
26.​What are complications of subdural or subarachnoid hematomas?
●​ Pressure, brain damage.
27.​What complications can result from meningitis?
●​ Infection, increased pressure.
28.​Where are the cranial dural septa located?
●​ Falx cerebri: between cerebral hemispheres; Falx cerebelli: between cerebellar
hemispheres; Tentorium cerebelli: separates cerebrum/cerebellum.
29.​What are the four brain ventricles and their locations?
●​ Lateral (cerebrum), third (diencephalon), fourth (brainstem/cerebellum).
30.​What cells line brain ventricles and their function?
●​ Ependymal cells: circulate CSF.
31.​How is CSF formed, circulated, and removed?
●​ Made in choroid plexus → ventricles → subarachnoid space → arachnoid villi →
dural sinuses.
32.​What are the functions of CSF?
●​ Cushions, nutrients, waste removal.
33.​What happens if CSF flow is blocked?
●​ Hydrocephalus: fluid buildup.
34.​What makes up the blood-brain barrier?
●​ Endothelial cells, astrocytes, tight junctions.
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