t t lo t t t t
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t t t t t t t t t
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t t
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t t lo t t t t
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t t
Chapter 01: Drug Regulation,Actions, and Responses
t t t t t t
Workman & LaCharity: Understanding Pharmacology: Essentials forMedication Safety, 2ndEdi tion
t t t t t t t t t t
MULTIPLE CHOICE B t t
t ASIC CONCEPTS t
1. Which health care professional has the major responsibilityfor dispensing prescribed
t t t t t t t t t t
drugs under the direction of a pharmacist?
t t t t t t t
a. Physician
b Nurse practitioner t
.
c. Licensed nurse t
d Pharmacy technician lo
.
ANS: D t t
The physician and nurse practitioner have the major responsibility for prescribing drugs, not dis
t t t t t t t t t t t t t
pensing them. The licensed nurse has the primary responsibility for administering drugs, althou gh
t t t t t t t t t t t t t t
under some circumstances a licensed nurse may dispense prescribed drugs but this isnot his o r her
t t t t t t t t t t t t t t t t t
major responsibility in drug therapy. The pharmacy technician has the major responsibility of
t t t t t t t t t t t t t
dispensing prescribed drugs under the direction of a licensed pharmacist.
t t t t t t t t t t
DIF: t t Cognitive Level: Remembering t t t t t t REF: t t p. 3 t
2. Which term describes the effect of a drug that improves body function?
t t t t t t t lo t t t
a. Side effect t
b Intended action lo
.
c. Adverse reaction t
d Idiosyncratic response t
.
ANS: B t t
The purpose of drug therapy is to take a drug to prevent, reduce, or correct a health problem
t t t t t t t t t lo t t t t t t t
.This response is any drug’s intended action also known as a therapeutic response.
t t t t t t t t t t t t
DIF:
t Cognitive Level: Remembering t t REF: p. 3 t
3. Which type of drug name is ―owned‖ by the company that manufactures it? t t t t t t t t t t t t
a. Generic name t
b Chemical name t
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t t
.
c. Category name t
d Trade name lo
.
ANS: D t t
The chemical name is a drug’s exact chemical composition. The generic name is the name assig
t t t t t t t t t t t t t t t
ned to the drug by the U.S. Adopted Names Council and is not owned by anyone. The category
t t t t t t t t t t t t t t t t t t
name refers to the type of drug (what it does or what it is used for) and is not an actual drug nam
t t t t t t t t t t t t t t t t t t t t t lo t
e. The trade name (brand name) is the name provided and owned by a specific drug’s manufact
t t t t t t t t t t t t t t t t
urer.
t
DIF: t t Cognitive Level: Remembering t t t t t t REF: t t p. 4 t
4. Which drug or drug class is a ―high alert‖ drug? lo lo lo lo lo lo lo lo lo
a. Penicillin
b Insulin
.
c. NSAIDs
d Calcium
.
ANS: B
A high alert drug is one in which harm is likely to result if given at the wrong dose, to the wrong
t t t t t t t t t t t t t t t t t t t t t lo
tpatient, or not given to the correct patient. Drugs classified as high alert drugs include potassium
t t t t t t t t t t t t t t t
,narcotics (opioids), insulin, cancer chemotherapy drugs, and heparin (or any drug that strongly a ffects
t t t t t t t t t t t t t t
blood clotting). Penicillin, NSAIDs, and calcium are not considered high alert drugs.
t t t t t t t t t t t t
DIF: Cognitive Level: Remembering t t REF: p. 4 t
5. What is the term for a drug that has the same action as a naturally occurring bod
t t t t t t t t t t t t t t t t
yhormone or enzyme?
t t t
a. Agonist
b Blocking agent t
.
c. Chemical
d Duplicator
.
ANS: A
A drug agonist is an extrinsic drug that activates the receptor sites of a cell and mimics th
t t t t t t t t t t t t t t t t t
eactions of naturally occurring body substances (intrinsic drugs). A blocking agent is a dru g
t t t t t t t t t t t t t t t
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t t t t t t t t t
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t t
antagonist. A chemical would not necessarily be a drug at all. A duplicator is not a pharmacologict erm.
t t t t t t t t t t t t t t t t t
DIF: t t Cognitive Level: Remembering t t t t t t REF: t t pp. 6-7 t
6. Which term describes how the body affects drug activity? t t t t t t t t
a. Drug potency t
b Pharmacodynamics
.
c. Therapeutic effect t
d Pharmacokinetics
.
ANS: D t t
The term pharmacokinetics refers to drug metabolism and how the body changes a drug. Pharmac
t t t t t t t t t t t t t t
odynamics refers to how a drug works to change body function. Drug potency refers tohow strongl y
t t t t t t t t t t t t lo t t t t
or to what degree a drug exerts its effects. The therapeutic effect is closer to pharmacodynamics
t t t t t t t t t t t t t t t t
, meaning how a drug works to change body function. DIF:
t t t t t t t t t t
Cognitive Level: Remembering t t REF: p. 10 t
7. In the United States, which group is responsible for enforcing established standards for
t t t t t t t t t t t t
drug manufacturing?
t t
a. U.S. Pharmacopeia t
b National Institutes of Health t t t
.
c. Food and Drug Administration lo lo lo
d Association of Pharmaceutical Manufacturers t t t
.
ANS: C
The standards for drug manufacture are established by the U.S. Pharmacopeia. These standards are
t t t t t t t t t t t t t
enforced by the Food and Drug Administration. Neither the National Institutes of Health nort
t t t l t t t lo t t t t t t t
heAssociation of Pharmaceutical Manufacturers has any authority to enforce drug standards.
t t t t t t t t t t t t
DIF: Cognitive Level: Remembering t t REF: p. 5 t
8. Which factor is a major disadvantage of the transdermal drug delivery route?
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a. Only a prescriber can administer drugs by the transdermal route.
t t t t t t t t t
b Transdermal drugs must be sterile rather than clean. t t t t t t t
.
c. First pass drug loss by this route is the most extensive.
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d Drug absorption is dependent on adequate circulation.
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