Mark Comprehensive Clinical Medicine Self-Assessment 1 hr 14 min 48 sec
1. A 56-year-old man comes to the office because of a 6-week history of increasing urinary frequency and thirst. During this time, he has been urinating large volumes throughout the day and has felt tired. He has not had pain on urination
or blood in his urine. Medical history is unremarkable and the patient takes no medications. He drinks 12 beers daily. He does not smoke cigarettes. BMI is 32 kg/m 2. Vital signs are temperature 37.0°C (98.6°F), pulse 98/min,
respirations 16/min, and blood pressure 118/76 mm Hg. Physical examination discloses no abnormalities. Results of fasting laboratory studies are shown:
Serum Blood
Urea nitrogen 18 mg/dL Hemoglobin A 1c 12.0%
Creatinine 1.7 mg/dL
Na * 140 mEq/L
K+ 4.0 mEq/L
Cl- 100 mEq/L
HCO 3- 25 mEq/L
Glucose 272 mg/dL
Urine dipstick shows large ketones. In addition to lifestyle modifications, which of the following is the most appropriate pharmacotherapy?
O A ) Glipizide
O B ) Insulin
O C ) Metformin
O D ) Rosiglitazone
O E ) Sitagliptin
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,Exam Section 1 Item: 2 of 50 National Board of Medical Examiners® Time Remaining:
Mark Comprehensive Clinical Medicine Self-Assessment 1 hr 13 min 38 sec
2. A 68-year-old man comes to the clinic because of a sore on his lower lip that began as an irritation 1 month ago and has progressed to an intermittently painful lesion with drainage. The patient's ability to eat and drink has not been
affected. He has noticed no other skin lesions and notes no other symptoms. Medical history is significant for prostate cancer and hypertension. His only medication is chlorthalidone. He is a retired construction worker. He has smoked
one pack of cigarettes daily for the past 50 years. He has been sexually active with multiple partners and does not use condoms. Vital signs are temperature 37.0°C (98.6°F), pulse 82/min, respirations 12/min, and blood pressure
132/78 mm Hg. Physical examination discloses the findings shown in the photograph. The remainder of the examination shows no abnormalities. Which of the following is the most likely diagnosis?
O A ) Basal cell carcinoma
O B ) Kaposi sarcoma
O C ) Melanoma
O D ) Merkel cell carcinoma
O E ) Squamous cell carcinoma
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,Exam Section 1 Item: 3 of 50 National Board of Medical Examiners® Time Remaining:
Mark Comprehensive Clinical Medicine Self-Assessment 1 hr 12 min 29 sec
3. A 93-year-old woman comes to the office as a new patient. She feels well. She has hyperlipidemia treated with atorvastatin. She has no other history of serious illness and takes no other medications. Her last colonoscopy 25 years ago
and her last mammography and DEXA scan 30 years ago showed no abnormalities. Vital signs are within normal limits. Examination shows no abnormalities. The patient asks what preventive health measures she should take. Which of
the following is the most appropriate physician response?
O A ) "At this stage, you seem to be doing really well, so I wouldn't recommend any further preventive measures."
O B ) "Continued adherence to your medication regimen is the best preventive measure for you."
O C ) "Vaccinations are important for preventing serious illnesses , especially as we get older."
O -
D ) "Weight bearing exercise is unlikely to impact your health at your age."
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, Exam Section 1 Item: 4 of 50 National Board of Medical Examiners® Time Remaining:
Mark Comprehensive Clinical Medicine Self-Assessment 1 hr 11 min 15 sec
4 . A researcher is investigating the rate of type 2 diabetes mellitus among residents of a town in the midwestern United States. A total of 10,000 people live in the town, and 400 of these residents have been diagnosed with type 2 diabetes
mellitus. Over the next 6 months, an additional 100 residents are diagnosed with type 2 diabetes mellitus. There has been no migration of people into or out of the town during this period of time. Based on this information, which of the
following best represents the annualized incidence rate of type 2 diabetes mellitus in this town?
O A ) 2 x ()
O B) 2 x (,000)
O C ) 2 x ()
O D ) 2 x (,000)
O E )
O F ) ,000
O G )
O H ) ,000
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