TEST BANK FOR: Fundamentals of Molecular Virology 2nd Edition by Nicholas H. Acheson Latest Update.

, TEST BANK for Fundamentals of MolecularVirology 2nd
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Edition by Acheson. t t t




Package Title: Testbank
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Course Title: Acheson 2nd edition
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Chapter Number: 01
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Question type: Multiple Choice
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1) Which of the following terms describes the protein shell that surrounds the viral genome?
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a) capsid
b) envelope
c) matrix
d) virion
e) capsomere

Answer: a
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2) Which of the following would not be a nucleic acid form found in a viral genome?
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a) dsDNA
b) ssDNA
c) dsRNA
d) ssRNA
e) an RNA:DNA hybrid
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Answer: e
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3) Which of the following is an enzyme that most RNA viruses encode in their genome?
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a) DNA-dependent-RNA-polymerase
b) RNA-dependent-RNA-polymerase
c) DNA-dependent-DNA-polymerase
d) DNA-dependent-RNA-polymerase
e) RNA-dependent-protein-synthetase

Answer: b
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4) Viruses play a major role in the ecology of the ocean by doing which of the following?
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a) By infecting photosynthetic bacteria and increasing their growth.
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,b) By infecting harmful bacteria found in the ocean and limiting their growth.
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c) By killing off fish and preventing them from becoming too plentiful.
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d) By lysing unicellular organisms and releasing carbon and oxygen back into the ocean.
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e) All of the above statements are correct.
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Answer: d t




5) If you wanted to show that an infectious agent is a virus, what experiment could you do?
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a) Show that the agent can be seen under a light microscope.
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b) Show that agent contains a lipid membrane.
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c) Show that the agent can form single colonies on an agar plate.
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d) Show that the agent can be diluted and can still cause disease in an animal.
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e) Show that the agent can pass through a porcelain filter and is still infectious.
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Answer: e t




6) What does the word “virus” mean in Latin?
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a) infectious agent t


b) liquid
c) poison
d) death
e) disease

Answer: c
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7) The word “phage” is a shortened version of the name of a virus that can infect which type of
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organism?

a) bacterial cell t


b) human cell t


c) eukaryotic cell t


d) plant cell t


e) inset cell t




Answer: a
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8) The study of which group of viruses led to the discovery of cellular genes that can promoter cancer in
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animal cells?
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a) papillomaviruses
b) retroviruses
c) adneoviruses
d) polyomaviruses

, e) picornaviruses

Answer: b
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9) When doing a plaque assay with human or animal cells, a layer of nutrient media mixed with agar is
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put on top of the cells after they have been infected with the diluted virus. What is the major purpose of
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this agar layer?
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a) It helps to feed the cells as they grow.
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b) It promotes the replication of the virus.
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c) It makes the infected cells easier to visualize.
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d) It limits the movement of virus particles.
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e) All of the above are correct.
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Answer: d t




10) To start an experiment, you do an infection by putting 0.5 ml of a virus stock that has a titer of 6 x
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107 pfu/ml onto a plate of animal cells that contains 5 x 106 cells. What is the multiplicity of infection for
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this experiment?
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a) 12
b) 6
c) 5
d) 3
e) 1

Answer: b
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11) During a single growth cycle experiment, the titer of extracellular and intracellular virus drops in the
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first hour. What explains this observation?
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a) The virus is inactivated by antibodies in the medium.
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b) The virus is inactivated by cellular enzymes.
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c) The virus enters the cell and is uncoated.
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d) The virus binds to the cells in the dish and can’t be released.
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e) The cell’s antiviral defenses prevent replication of the virus
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Answer: c t




12) What is another term for an RNA-dependent-DNA-polymerase?
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a) DNA polymerase t


b) RNA polymerase II t t