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GCSE Biology – Complete Study Guide | Cell Biology, Microscopy, Transport & Respiration | Structured Q&A Format

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This comprehensive GCSE Biology resource covers key exam topics including cell structures, differences between plant and animal cells, organelles and their functions, diffusion, osmosis, active transport, microscopy, the cell cycle, stem cells, and respiration. Presented in a clear question-and-answer format, it helps students revise efficiently and understand core biological principles. Ideal for GCSE students preparing for assessments or exams, especially those revising for AQA, Edexcel, or OCR specifications.

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Uploaded on
May 10, 2025
Number of pages
24
Written in
2024/2025
Type
Exam (elaborations)
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Questions & answers

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GCSE Biology
What are the differences between plant and animal cells? ✔✔Plant
> has a cell wall
> only one vacuole
> chloroplasts

Animal
> no cell wall
> multiple vacuoles
> no chloroplasts


List all of the organelles which define an animal cell. ✔✔> nucleus
> cell membrane
> cytoplasm
> vacuoles
> mitochondria


What is the function of the nucleus? ✔✔contains genetic information contained in chromosomes
which are assembled into DNA


Which cell organelle is responsible for protein synthesis? ✔✔ribosomes


Which cell organelle contains chlorophyll and is the site of photosynthesis? ✔✔chloroplast


Where is the site of aerobic respiration in a cell? ✔✔mitochondria


What is the function of vacuoles? ✔✔storage > contain a solution


What is a cell wall made of? ✔✔cellulose


Describe the function of the cytoplasm. ✔✔clear jelly which contains dissolved substances >
site of many metabolic reactions

,How many nanometres are in a metre? ✔✔1 billion or 1x10^9


What are the differences between a light and electron microscope? ✔✔> electron microscopes
have a higher magnification and resolution

> in light microscopes, the source of the image is light waves whereas in electron microscopes
the source of the image is electron beams

> electron microscopes are more expensive

> the specimen has to be dead to view it under an electron microscope but a light microscope can
view either live or dead specimens

> in a light microscope the image is moving and in colour but in an electron microscope the
image is still and in black and white

> light microscope preparation is chemicals but electron microscope preparation is more
complex and the specimen has to be coated in materials and dehydrated

What are the differences between the scanning (SEM) and transmission electron microscopes
(TEM)? ✔✔> SEM is used to scan external features
> TEM is used to view internal features


What is the difference between magnification and resolution? ✔✔magnification tells us how
much bigger the image will appear, resolution is how clear the image is


What are the 7 characteristics of life? ✔✔MRSGREN


Movement
Respiration
Sensitivity
Growth
Reproduction
Excretion
Nutrition

, What is the equation for magnification? ✔✔magnification = image size / actual size


What features of a sperm cell make them suitable for sexual reproduction? ✔✔> flagellum
which helps them move towards the egg
> haploids (one set of chromosomes)
> mitochondria to give them energy from respiration to move


What are the differences between prokaryotic and eukaryotic cells? ✔✔prokaryotic cells do not
have DNA contained inside a nucleus or organelles


Why are viruses not considered living? ✔✔they cannot reproduce by themselves > which is one
of the MRSGREN requirements


How do bacteria divide? ✔✔binary fission


What are the 3 phases of the cell cycle? ✔✔1. Interphase
2. Mitosis
3. Cytokinesis


What are the 3 stages of interphase? ✔✔1. G1 > the cell carries out normal activities e.g
respiration

2. S > DNA replicates to form two copies of each chromosome

3. G2 > further growth occurs; organelles such as mitochondria replicate and the DNA is
checked for errors and any repairs are made


What happens during mitosis and cytokinesis? ✔✔Mitosis > the stage where the chromosomes
separate and the nucleus divides into 2 within the cell

Cytokinesis > the stage where cells physically divide into 2


What are stem cells? ✔✔undifferentiated cells with the potential to divide and produce new
specialised cells such as nerve cells or muscle cells
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