NUR 465 Final Exam 1 Questions With
All Solved Solutions.
Pharmacologic Class - Answer How the drug works @ molecular, tissue or body system level
ex = "vasodilator" makes blood vessels wider -- "vaso-" refers to blood vessels which are tissues
Med Administration TL - Answer 1) 1906 Pure Food & Drug Act: Prohibits drugs which are
misbranded or adulterated
2) 1912: Cannot make false claims
3) 1938: Drugs have to be tested
4) 1975: One standardized publication so everyone is working with the same information
5) 1994: Clear labeling of dietary supplements
6) 2002: Working on safety and efficacy for pediatric drugs
Preclinical Testing - Answer Performed @ cellular level of animals to look for risks in humans
Toxicities
Pharmacokinetic properties
Potentially useful biologic effects
Takes 1-5 yrs then can trial drug on humans
Stage 2 of Testing (clinical phase) - Answer *Phase 1:* Testing on volunteers to determine
, - Does the drug make other medical conditions worse?
- Does the drug interact with other medications?
- Does the drug effect all of the people in the same way or are there differences, such as men
vs. women?
Stage 3 of testing- New drug application review - Answer Trade name finalized & trials
continue on animals/people
Stage 4 of testing - Post-marketing surveillance - Answer clinical trials/nda is completed
Goal = give drug to reg. pop.
Clinical Testing w/o human or animal subjects? - Answer by using a silicon chip that holds
blood/tissue & new drug --> mimics response of a live subject
Drug Schedules - Answer
RN Responsibilities - Answer - Know when a drug is indicated
- Know when a drug is appropriate
- Know when an adverse event has occurred
- Know what to do when something goes wrong
- Utilize the available resources to ensure safe nursing practice
Core Pt Variables/Core Drug Knowledge - Answer - Factors that are unique to each person
- Factors that are unique to a drug
- Not everyone responds the same way
- Not all responses can be anticipated
- CPV's (i.e liver disease, genetic diseases, environment, lifestyle/diet, culture, etc.)
Allergic reaction - Answer Acquired hyper response of body
Signs = rash, edema, runny nose, red eyes, anaphylaxis
All Solved Solutions.
Pharmacologic Class - Answer How the drug works @ molecular, tissue or body system level
ex = "vasodilator" makes blood vessels wider -- "vaso-" refers to blood vessels which are tissues
Med Administration TL - Answer 1) 1906 Pure Food & Drug Act: Prohibits drugs which are
misbranded or adulterated
2) 1912: Cannot make false claims
3) 1938: Drugs have to be tested
4) 1975: One standardized publication so everyone is working with the same information
5) 1994: Clear labeling of dietary supplements
6) 2002: Working on safety and efficacy for pediatric drugs
Preclinical Testing - Answer Performed @ cellular level of animals to look for risks in humans
Toxicities
Pharmacokinetic properties
Potentially useful biologic effects
Takes 1-5 yrs then can trial drug on humans
Stage 2 of Testing (clinical phase) - Answer *Phase 1:* Testing on volunteers to determine
, - Does the drug make other medical conditions worse?
- Does the drug interact with other medications?
- Does the drug effect all of the people in the same way or are there differences, such as men
vs. women?
Stage 3 of testing- New drug application review - Answer Trade name finalized & trials
continue on animals/people
Stage 4 of testing - Post-marketing surveillance - Answer clinical trials/nda is completed
Goal = give drug to reg. pop.
Clinical Testing w/o human or animal subjects? - Answer by using a silicon chip that holds
blood/tissue & new drug --> mimics response of a live subject
Drug Schedules - Answer
RN Responsibilities - Answer - Know when a drug is indicated
- Know when a drug is appropriate
- Know when an adverse event has occurred
- Know what to do when something goes wrong
- Utilize the available resources to ensure safe nursing practice
Core Pt Variables/Core Drug Knowledge - Answer - Factors that are unique to each person
- Factors that are unique to a drug
- Not everyone responds the same way
- Not all responses can be anticipated
- CPV's (i.e liver disease, genetic diseases, environment, lifestyle/diet, culture, etc.)
Allergic reaction - Answer Acquired hyper response of body
Signs = rash, edema, runny nose, red eyes, anaphylaxis
