Summary Biochemistry Notes: Krebs Cycle

TCA


Enzyme Class Substrate Product NADH FADH2 ATP CO2
made? made? made? lost?
Pyruvate Oxidoreductase Pyruvate Acetyl CoA 2 per No No 2 per
dehydrogenase glucose glucose

Citrate Ligase Acetyl CoA Citrate No No No No
synthase and
Oxaloacetate

Aconitase Isomerase Citrate Isocitrate No No No No
Isocitrate Oxidoreductase Isocitrate a- 2 per No No 2 per
dehydrogenase Ketoglutarate glucose glucose

a- Oxidoreductase a- Succinyl-CoA 2 per No No 2 per
Ketoglutarate Ketoglutarate glucose glucose
dehydrogenase

Succinyl-CoA Ligase Succinyl-CoA Succinate No No 2 per No
synthetase glucose


Succinate Oxidoreductase Succinate Fumarate No 2 per No No
dehydrogenase glucose


Fumarase Ligase Fumarate Malate No No No No



Malate Oxidoreductase Malate Oxaloacetate 2 per No No No
dehydrogenase glucose