COMPLETE TEST BANK FOR
MCCANCE & HUETHER’S PATHOPHYSIOLOGY,
9TH EDITION
COVERED CHAPTERS 1-50|100%VERIFIED ANSWERS BY
ROGERS
,TABLE OF CONTENTS
Chapter 1: Cellular Biology .................................................................................................................4
Chapter 2: Altered Cellular And Tissue Biology .................................................................................. 24
Chapter 3: The Cellular Environment: Fluids And Electrolytes, Acids And Bases .................................. 42
Chapter 4: Genes And Genetic Diseases ............................................................................................ 61
Chapter 5: Genes, Environment-Lifestyle, And Common Diseases...................................................... 76
Chapter 6: Epigenetics And Disease .................................................................................................. 89
Chapter 7: Innate Immunity: Inflammation ....................................................................................... 95
Chapter 8: Adaptive Immunity........................................................................................................ 116
Chapter 9: Alterations In Immunity And Inflammation .................................................................... 133
Chapter 10: Infection ..................................................................................................................... 150
Chapter 11: Stress And Disease ...................................................................................................... 164
Chapter 12: Cancer Biology............................................................................................................. 177
Chapter 13: Cancer Epidemiology ................................................................................................... 197
Chapter 14: Cancer In Children ....................................................................................................... 205
Chapter 15: Structure And Function Of The Neurologic System........................................................ 212
Chapter 16: Pain, Temperature Regulation, Sleep, And Sensory Function ........................................ 227
Chapter 17: Alterations In Cognitive Systems, Cerebral Hemodynamics, And Motor Function .......... 247
Chapter 18: Disorders Of The Central And Peripheral Nervous Systems And The Neuromuscular
Junction ......................................................................................................................................... 265
Chapter 19: Neurobiology Of Schizophrenia, Mood Disorders, And Anxiety Disorders ...................... 281
Chapter 20: Alterations Of Neurologic Function In Children ............................................................. 291
Chapter 21: Mechanisms Of Hormonal Regulation .......................................................................... 302
Chapter 22: Alterations Of Hormonal Regulation ............................................................................ 315
Chapter 23: Obesity And Disorders Of Nutrition .............................................................................. 332
Chapter 24: Structure And Function Of The Reproductive Systems .................................................. 342
Chapter 25: Alterations Of The Female Reproductive System .......................................................... 355
Chapter 26: Alterations Of The Male Reproductive System.............................................................. 368
Chapter 27: Sexually Transmitted Infections ................................................................................... 377
,Chapter 28: Structure And Function Of The Hematologic System ..................................................... 390
Chapter 29: Alterations Of Erythrocyte Platelet, Hemostatic Function ............................................. 405
Chapter 30: Alterations Of Leukocyte, Lymphoid Function .............................................................. 421
Chapter 31: Alterations Of Hematologic Function In Children .......................................................... 436
Chapter 32: Structure And Function Of The Cardiovascular And Lymphatic Systems ......................... 451
Chapter 33: Alterations Of Cardiovascular Function ........................................................................ 471
Chapter 34: Alterations Of Cardiovascular Function In Children ....................................................... 492
Chapter 35: Structure And Function Of The Pulmonary System........................................................ 504
Chapter 36: Alterations Of Pulmonary Function .............................................................................. 518
Chapter 37: Alterations Of Pulmonary Function In Children ............................................................. 541
Chapter 38: Structure And Function Of The Renal And Urologic Systems.......................................... 554
Chapter 39: Alterations Of Renal And Urinary Tract Function .......................................................... 568
Chapter 40: Alterations Of Renal And Urinary Tract Function In Children ......................................... 584
Chapter 41: Structure And Function Of The Digestive System .......................................................... 596
Chapter 42: Alterations Of Digestive Function ................................................................................. 612
Chapter 43: Alterations Of Digestive Function In Children ............................................................... 629
Chapter 44: Structure And Function Of The Musculoskeletal System ............................................... 643
Chapter 45: Alterations Of Musculoskeletal Function ...................................................................... 659
Chapter 46: Alterations Of Musculoskeletal Function In Children .................................................... 677
Chapter 47: Structure, Function, And Disorders Of The Integument ................................................. 689
Chapter 48: Alterations Of The Integument In Children ................................................................... 705
Chapter 49: Shock, Multiple Organ Dysfunction Syndrome, And Burns In Adults .............................. 715
Chapter 50: Shock, Multiple Organ Dysfunction Syndrome, And Burns In Children ........................... 728
,Chapter 1: Cellular Biology
MULTIPLE CHOICE
1. Which Statement Best Describes The Cellular Function Of Metabolic Absorption?
A. Cells Can Produce Proteins. C. Cells Can Take In And Use Nutrients.
B. Cells Can Secrete Digestive Enzymes. D. Cells Can Synthesize Fats.
Ans:C
In Metabolic Absorption, All Cells Take In And Use Nutrients And Other Substances From Their
Surroundings. The Remaining Options Are Not Inclusive In Their Descriptions Of Cellular Metabolic
Absorption.
Pts: 1 Ref: Page 2
2. Most Of A Cell’s Genetic Information, Including Rna And Dna, Is Contained In The:
A. Mitochondria C. Nucleolus
B. Ribosome D. Lysosome
Ans:C
The Nucleus Contains The Nucleolus, A Small Dense Structure Composed Largely Of Rna, Most Of The
Cellular Dna, And The Dna-Binding Proteins, Such As The Histones, Which Regulate Its Activity. The
Other Options Do Not Contain Most Of A Cell’s Genetic Information.
Pts: 1 Ref: Page 2
3. Which Component Of The Cell Produces Hydrogen Peroxide (H2o2) By Using Oxygen To
Remove Hydrogen Atoms From Specific Substrates In An Oxidative Reaction?
A. Lysosomes C. Ribosomes
B. Peroxisomes D. Oxyhydrosomes
Ans:B
Peroxisomes Are So Named Because They Usually Contain Enzymes That Use Oxygen To Remove
Hydrogen Atoms From Specific Substrates In An Oxidative Reaction That Produces H2o2, Which Is A
Powerful Oxidant And Potentially Destructive If It Accumulates Or Escapes From Peroxisomes.
,Ribosomes Are Rna-Protein Complexes (Nucleoproteins) That Are Synthesized In The Nucleolus And
Secreted Into The Cytoplasm Through Pores In The Nuclear Envelope Called Nuclear Pore Complexes.
Lysosomes Are Saclike Structures That Originate From The Golgi Complex And Contain More Than 40
Digestive Enzymes Called Hydrolases, Which Catalyze Bonds In Proteins, Lipids, Nucleic Acids, And
Carbohydrates. Oxyhydrosomes Are Involved In Enzyme Production.
Pts: 1 Ref: Page 8
4. Which Cell Component Is Capable Of Cellular Autodigestion When It Is Released During Cell
Injury?
A. Ribosome C. Smooth Endoplasmic Reticulum
B. Golgi Complex D. Lysosomes
Ans:D
The Lysosomal Membrane Acts As A Protective Shield Between The Powerful Digestive Enzymes
Within The Lysosome And The Cytoplasm, Preventing Their Leakage Into The Cytoplasmic Matrix.
Disruption Of The Membrane By Various Treatments Or Cellular Injury Leads To A Release Of The
Lysosomal Enzymes, Which Can Then React With Their Specific Substrates, Causing Cellular Self-
Digestion. The Other Options Do Not Correctly Describe This Process.
Pts: 1 Ref: Pages 7-8
5. What Is The Sequence Of Steps In The Development Of A Digestive Enzyme By The Pancreas
Cells From The Initial Transcription To The Release From The Cell?
A. The Enzyme Is Transcribed From Dna By Rna In The Nucleus, Proceeds To The Ribosome For
Synthesis, And Is Transported In A Secretory Vesicle To The Cell Membrane.
B. The Enzyme Is Transcribed From Rna By Dna In The Nucleus, Proceeds To The Lysosome For
Synthesis, And Is Transported In An Encapsulated Membrane To The Cell Membrane.
C. The Enzyme Is Transcribed By The Mitochondria In The Nucleus, Proceeds To The Ribosome For
Synthesis, And Is Transported In A Cytoskeleton To The Cell Membrane.
D. The Enzyme Is Transcribed From Dna By Rna In The Nucleus, Proceeds To The Golgi Complex
For Synthesis, And Is Transported In A Cytosol To The Cell Membrane.
Ans:A
,The Enzyme Is Transcribed From Dna By Rna In The Nucleus, Proceeds To The Ribosome For Synthesis,
And Is Transported In A Secretory Vesicle To The Cell Membrane. The Other Options Do Not Correctly
Describe This Process.
Pts: 1 Ref: Page 7 | Figure 1-5
6. During Which Phase Of The Cell Cycle Is Dna Synthesized?
A. G1 C. G2
B. S D. M
Ans:B
The Four Designated Phases Of The Cell Cycle Are: (1) The G1 Phase (G = Gap), Which Is The Period
Between The M Phase (M = Mitosis) And The Start Of Dna Synthesis; (2) The S Phase (S = Synthesis),
During Which Dna Is Synthesized In The Cell Nucleus; (3) The G2 Phase, During Which Rna And Protein
Synthesis Occurs, The Period Between The Completion Of Dna Synthesis And The Next Phase (M); And
(4) The M Phase, Which Includes Nuclear And Cytoplasmic Division.
Pts: 1 Ref: Page 37
7. What Organic Compound Facilitates Transportation Across Cell Membranes By Acting As
Receptors, Transport Channels For Electrolytes, And Enzymes To Drive Active Pumps?
A. Lipids C. Proteins
B. Proteases D. Carbohydrates
Ans:C
Proteins Act As
(1) Recognition And Binding Units (Receptors) For Substances Moving In And Out Of The Cell;
(2) Pores Or Transport Channels For Various Electrically Charged Particles Called Ions Or Electrolytes
And Specific Carriers For Amino Acids And Monosaccharides; And
(3) Specific Enzymes That Drive Active Pumps That Promote The Concentration Of Certain Ions,
Particularly Potassium (K+), Within The Cell While Keeping Concentrations Of Other Ions, For Example,
Sodium (Na+), Below The Concentrations Found In The Extracellular Environment. The Other Options
Do Not Correctly Describe This Process.
, Pts: 1 Ref: Page 13 | Page 15
8. Understanding The Various Steps Of Proteolytic Cascades, Such As Caspase-Mediated
Apoptosis And Complement Cascades, May Be Useful In Designing Drug Therapy For Which Human
Diseases?
A. Cardiac And Vascular Disorders
B. Autoimmune And Malignant Disorders
C. Gastrointestinal And Renal Disorders
D. Endocrine And Gastrointestinal Disorders
Ans:B
Understanding The Various Steps Involved In This Process Is Crucial For Designing Drug Interventions.
Dysregulation Of Proteases Features Prominently In Many Human Diseases, Including Cancer,
Autoimmunity, And Neurodegenerative Disorders. The Other Options Do Not Correctly Describe This
Process.
Pts: 1 Ref: Page 15
9. Which Structure Prevents Water-Soluble Molecules From Entering Cells Across The Plasma
Membrane?
A. Carbohydrate Chains C. Membrane Channel Proteins
B. Glycoprotein Channels D. Lipid Bilayer
Ans:D
The Bilayer’s Structure Accounts For One Of The Essential Functions Of The Plasma Membrane. It Is
Impermeable To Most Water-Soluble Molecules (Molecules That Dissolve In Water) Because The
Water-Soluble Molecules Are Insoluble In The Oily Core Region. The Bilayer Serves As A Barrier To The
Diffusion Of Water And Hydrophilic Substances While Allowing Lipid-Soluble Molecules, Such As
Oxygen (O2) And Carbon Dioxide (Co2), To Diffuse Through It Readily. The Other Options Do Not
Correctly Describe This Process.
MCCANCE & HUETHER’S PATHOPHYSIOLOGY,
9TH EDITION
COVERED CHAPTERS 1-50|100%VERIFIED ANSWERS BY
ROGERS
,TABLE OF CONTENTS
Chapter 1: Cellular Biology .................................................................................................................4
Chapter 2: Altered Cellular And Tissue Biology .................................................................................. 24
Chapter 3: The Cellular Environment: Fluids And Electrolytes, Acids And Bases .................................. 42
Chapter 4: Genes And Genetic Diseases ............................................................................................ 61
Chapter 5: Genes, Environment-Lifestyle, And Common Diseases...................................................... 76
Chapter 6: Epigenetics And Disease .................................................................................................. 89
Chapter 7: Innate Immunity: Inflammation ....................................................................................... 95
Chapter 8: Adaptive Immunity........................................................................................................ 116
Chapter 9: Alterations In Immunity And Inflammation .................................................................... 133
Chapter 10: Infection ..................................................................................................................... 150
Chapter 11: Stress And Disease ...................................................................................................... 164
Chapter 12: Cancer Biology............................................................................................................. 177
Chapter 13: Cancer Epidemiology ................................................................................................... 197
Chapter 14: Cancer In Children ....................................................................................................... 205
Chapter 15: Structure And Function Of The Neurologic System........................................................ 212
Chapter 16: Pain, Temperature Regulation, Sleep, And Sensory Function ........................................ 227
Chapter 17: Alterations In Cognitive Systems, Cerebral Hemodynamics, And Motor Function .......... 247
Chapter 18: Disorders Of The Central And Peripheral Nervous Systems And The Neuromuscular
Junction ......................................................................................................................................... 265
Chapter 19: Neurobiology Of Schizophrenia, Mood Disorders, And Anxiety Disorders ...................... 281
Chapter 20: Alterations Of Neurologic Function In Children ............................................................. 291
Chapter 21: Mechanisms Of Hormonal Regulation .......................................................................... 302
Chapter 22: Alterations Of Hormonal Regulation ............................................................................ 315
Chapter 23: Obesity And Disorders Of Nutrition .............................................................................. 332
Chapter 24: Structure And Function Of The Reproductive Systems .................................................. 342
Chapter 25: Alterations Of The Female Reproductive System .......................................................... 355
Chapter 26: Alterations Of The Male Reproductive System.............................................................. 368
Chapter 27: Sexually Transmitted Infections ................................................................................... 377
,Chapter 28: Structure And Function Of The Hematologic System ..................................................... 390
Chapter 29: Alterations Of Erythrocyte Platelet, Hemostatic Function ............................................. 405
Chapter 30: Alterations Of Leukocyte, Lymphoid Function .............................................................. 421
Chapter 31: Alterations Of Hematologic Function In Children .......................................................... 436
Chapter 32: Structure And Function Of The Cardiovascular And Lymphatic Systems ......................... 451
Chapter 33: Alterations Of Cardiovascular Function ........................................................................ 471
Chapter 34: Alterations Of Cardiovascular Function In Children ....................................................... 492
Chapter 35: Structure And Function Of The Pulmonary System........................................................ 504
Chapter 36: Alterations Of Pulmonary Function .............................................................................. 518
Chapter 37: Alterations Of Pulmonary Function In Children ............................................................. 541
Chapter 38: Structure And Function Of The Renal And Urologic Systems.......................................... 554
Chapter 39: Alterations Of Renal And Urinary Tract Function .......................................................... 568
Chapter 40: Alterations Of Renal And Urinary Tract Function In Children ......................................... 584
Chapter 41: Structure And Function Of The Digestive System .......................................................... 596
Chapter 42: Alterations Of Digestive Function ................................................................................. 612
Chapter 43: Alterations Of Digestive Function In Children ............................................................... 629
Chapter 44: Structure And Function Of The Musculoskeletal System ............................................... 643
Chapter 45: Alterations Of Musculoskeletal Function ...................................................................... 659
Chapter 46: Alterations Of Musculoskeletal Function In Children .................................................... 677
Chapter 47: Structure, Function, And Disorders Of The Integument ................................................. 689
Chapter 48: Alterations Of The Integument In Children ................................................................... 705
Chapter 49: Shock, Multiple Organ Dysfunction Syndrome, And Burns In Adults .............................. 715
Chapter 50: Shock, Multiple Organ Dysfunction Syndrome, And Burns In Children ........................... 728
,Chapter 1: Cellular Biology
MULTIPLE CHOICE
1. Which Statement Best Describes The Cellular Function Of Metabolic Absorption?
A. Cells Can Produce Proteins. C. Cells Can Take In And Use Nutrients.
B. Cells Can Secrete Digestive Enzymes. D. Cells Can Synthesize Fats.
Ans:C
In Metabolic Absorption, All Cells Take In And Use Nutrients And Other Substances From Their
Surroundings. The Remaining Options Are Not Inclusive In Their Descriptions Of Cellular Metabolic
Absorption.
Pts: 1 Ref: Page 2
2. Most Of A Cell’s Genetic Information, Including Rna And Dna, Is Contained In The:
A. Mitochondria C. Nucleolus
B. Ribosome D. Lysosome
Ans:C
The Nucleus Contains The Nucleolus, A Small Dense Structure Composed Largely Of Rna, Most Of The
Cellular Dna, And The Dna-Binding Proteins, Such As The Histones, Which Regulate Its Activity. The
Other Options Do Not Contain Most Of A Cell’s Genetic Information.
Pts: 1 Ref: Page 2
3. Which Component Of The Cell Produces Hydrogen Peroxide (H2o2) By Using Oxygen To
Remove Hydrogen Atoms From Specific Substrates In An Oxidative Reaction?
A. Lysosomes C. Ribosomes
B. Peroxisomes D. Oxyhydrosomes
Ans:B
Peroxisomes Are So Named Because They Usually Contain Enzymes That Use Oxygen To Remove
Hydrogen Atoms From Specific Substrates In An Oxidative Reaction That Produces H2o2, Which Is A
Powerful Oxidant And Potentially Destructive If It Accumulates Or Escapes From Peroxisomes.
,Ribosomes Are Rna-Protein Complexes (Nucleoproteins) That Are Synthesized In The Nucleolus And
Secreted Into The Cytoplasm Through Pores In The Nuclear Envelope Called Nuclear Pore Complexes.
Lysosomes Are Saclike Structures That Originate From The Golgi Complex And Contain More Than 40
Digestive Enzymes Called Hydrolases, Which Catalyze Bonds In Proteins, Lipids, Nucleic Acids, And
Carbohydrates. Oxyhydrosomes Are Involved In Enzyme Production.
Pts: 1 Ref: Page 8
4. Which Cell Component Is Capable Of Cellular Autodigestion When It Is Released During Cell
Injury?
A. Ribosome C. Smooth Endoplasmic Reticulum
B. Golgi Complex D. Lysosomes
Ans:D
The Lysosomal Membrane Acts As A Protective Shield Between The Powerful Digestive Enzymes
Within The Lysosome And The Cytoplasm, Preventing Their Leakage Into The Cytoplasmic Matrix.
Disruption Of The Membrane By Various Treatments Or Cellular Injury Leads To A Release Of The
Lysosomal Enzymes, Which Can Then React With Their Specific Substrates, Causing Cellular Self-
Digestion. The Other Options Do Not Correctly Describe This Process.
Pts: 1 Ref: Pages 7-8
5. What Is The Sequence Of Steps In The Development Of A Digestive Enzyme By The Pancreas
Cells From The Initial Transcription To The Release From The Cell?
A. The Enzyme Is Transcribed From Dna By Rna In The Nucleus, Proceeds To The Ribosome For
Synthesis, And Is Transported In A Secretory Vesicle To The Cell Membrane.
B. The Enzyme Is Transcribed From Rna By Dna In The Nucleus, Proceeds To The Lysosome For
Synthesis, And Is Transported In An Encapsulated Membrane To The Cell Membrane.
C. The Enzyme Is Transcribed By The Mitochondria In The Nucleus, Proceeds To The Ribosome For
Synthesis, And Is Transported In A Cytoskeleton To The Cell Membrane.
D. The Enzyme Is Transcribed From Dna By Rna In The Nucleus, Proceeds To The Golgi Complex
For Synthesis, And Is Transported In A Cytosol To The Cell Membrane.
Ans:A
,The Enzyme Is Transcribed From Dna By Rna In The Nucleus, Proceeds To The Ribosome For Synthesis,
And Is Transported In A Secretory Vesicle To The Cell Membrane. The Other Options Do Not Correctly
Describe This Process.
Pts: 1 Ref: Page 7 | Figure 1-5
6. During Which Phase Of The Cell Cycle Is Dna Synthesized?
A. G1 C. G2
B. S D. M
Ans:B
The Four Designated Phases Of The Cell Cycle Are: (1) The G1 Phase (G = Gap), Which Is The Period
Between The M Phase (M = Mitosis) And The Start Of Dna Synthesis; (2) The S Phase (S = Synthesis),
During Which Dna Is Synthesized In The Cell Nucleus; (3) The G2 Phase, During Which Rna And Protein
Synthesis Occurs, The Period Between The Completion Of Dna Synthesis And The Next Phase (M); And
(4) The M Phase, Which Includes Nuclear And Cytoplasmic Division.
Pts: 1 Ref: Page 37
7. What Organic Compound Facilitates Transportation Across Cell Membranes By Acting As
Receptors, Transport Channels For Electrolytes, And Enzymes To Drive Active Pumps?
A. Lipids C. Proteins
B. Proteases D. Carbohydrates
Ans:C
Proteins Act As
(1) Recognition And Binding Units (Receptors) For Substances Moving In And Out Of The Cell;
(2) Pores Or Transport Channels For Various Electrically Charged Particles Called Ions Or Electrolytes
And Specific Carriers For Amino Acids And Monosaccharides; And
(3) Specific Enzymes That Drive Active Pumps That Promote The Concentration Of Certain Ions,
Particularly Potassium (K+), Within The Cell While Keeping Concentrations Of Other Ions, For Example,
Sodium (Na+), Below The Concentrations Found In The Extracellular Environment. The Other Options
Do Not Correctly Describe This Process.
, Pts: 1 Ref: Page 13 | Page 15
8. Understanding The Various Steps Of Proteolytic Cascades, Such As Caspase-Mediated
Apoptosis And Complement Cascades, May Be Useful In Designing Drug Therapy For Which Human
Diseases?
A. Cardiac And Vascular Disorders
B. Autoimmune And Malignant Disorders
C. Gastrointestinal And Renal Disorders
D. Endocrine And Gastrointestinal Disorders
Ans:B
Understanding The Various Steps Involved In This Process Is Crucial For Designing Drug Interventions.
Dysregulation Of Proteases Features Prominently In Many Human Diseases, Including Cancer,
Autoimmunity, And Neurodegenerative Disorders. The Other Options Do Not Correctly Describe This
Process.
Pts: 1 Ref: Page 15
9. Which Structure Prevents Water-Soluble Molecules From Entering Cells Across The Plasma
Membrane?
A. Carbohydrate Chains C. Membrane Channel Proteins
B. Glycoprotein Channels D. Lipid Bilayer
Ans:D
The Bilayer’s Structure Accounts For One Of The Essential Functions Of The Plasma Membrane. It Is
Impermeable To Most Water-Soluble Molecules (Molecules That Dissolve In Water) Because The
Water-Soluble Molecules Are Insoluble In The Oily Core Region. The Bilayer Serves As A Barrier To The
Diffusion Of Water And Hydrophilic Substances While Allowing Lipid-Soluble Molecules, Such As
Oxygen (O2) And Carbon Dioxide (Co2), To Diffuse Through It Readily. The Other Options Do Not
Correctly Describe This Process.
