Multiple Sclerosis NSG 213, Test #1 Actual
Questions And Answers With Complete Solutions
2025
Multiple Sclerosis - ANSWER - Chronic, progressive degenerative disorder of
CNS
-Affects primarily white matter of the brain and spinal cord.
- It is classified as an autoimmune disease.
- Approximately 400,000 people in US have MS
-Onset between 20-50 years.
- High prevalence rate.
- Woman affected more often than men.
-Caucasian affected most
Multiple Sclerosis pt. 2 - ANSWER - Etiology - cause unknown
Risk factors:
,*Certain viral infections
* Immunological factors
* Environmental exposure (higher prevalence of MS in colder, more northern
latitudes)
* Genetic predisposition (positive family history)
Multiple Sclerosis Pathophysiology - ANSWER - Chronic progressive
degenerative neuroinflammatory disease that
affects myelin.
-Myelin is the protective sheath that covers the spinal cord and nerves.
* It protects nerves and help impulses travel along the nerve faster.
* These impulses control muscle movement as well as transmitting sensory data.
- CNS contains the blood brain barrier that separates circulating blood from the
brain's extracellular fluid.
* The barrier is composed of tight junctions between endothelial cells in the CNS
vessels that restrict the passage of solutes from the blood stream.
Pathophysiology - ANSWER - Demyelination is the loss of the myelin sheath.
- It begins with a breaking down of the blood brain barrier that allows
immune cells (T lymphocytes) to infiltrate and attack the myelin.
- In MS the immune system attacks the brain and spinal cord.
, - MS is characterized by the demyelination of the nerves in the CNS. Without
myelin, nerve impulses are slowed down and with destruction of the nerve axon,
the impulses are totally blocked.
Multiple Sclerosis
*Four Main types*
Type 1 - ANSWER 1. Relapsing-remitting MS (Most common form)
- Affects twice as many women than men (typically in their 20's and 30's)
- Characterized by clearly defined relapses (exacerbations) during which new
symptoms appear and old one worsen or reappear
- Relapse can last days or months; it is followed by periods of remissions during
which client as either a partial or total recovery
Multiple Sclerosis
*Four Main types*
Type 2 - ANSWER 2. Secondary-Progressive
Questions And Answers With Complete Solutions
2025
Multiple Sclerosis - ANSWER - Chronic, progressive degenerative disorder of
CNS
-Affects primarily white matter of the brain and spinal cord.
- It is classified as an autoimmune disease.
- Approximately 400,000 people in US have MS
-Onset between 20-50 years.
- High prevalence rate.
- Woman affected more often than men.
-Caucasian affected most
Multiple Sclerosis pt. 2 - ANSWER - Etiology - cause unknown
Risk factors:
,*Certain viral infections
* Immunological factors
* Environmental exposure (higher prevalence of MS in colder, more northern
latitudes)
* Genetic predisposition (positive family history)
Multiple Sclerosis Pathophysiology - ANSWER - Chronic progressive
degenerative neuroinflammatory disease that
affects myelin.
-Myelin is the protective sheath that covers the spinal cord and nerves.
* It protects nerves and help impulses travel along the nerve faster.
* These impulses control muscle movement as well as transmitting sensory data.
- CNS contains the blood brain barrier that separates circulating blood from the
brain's extracellular fluid.
* The barrier is composed of tight junctions between endothelial cells in the CNS
vessels that restrict the passage of solutes from the blood stream.
Pathophysiology - ANSWER - Demyelination is the loss of the myelin sheath.
- It begins with a breaking down of the blood brain barrier that allows
immune cells (T lymphocytes) to infiltrate and attack the myelin.
- In MS the immune system attacks the brain and spinal cord.
, - MS is characterized by the demyelination of the nerves in the CNS. Without
myelin, nerve impulses are slowed down and with destruction of the nerve axon,
the impulses are totally blocked.
Multiple Sclerosis
*Four Main types*
Type 1 - ANSWER 1. Relapsing-remitting MS (Most common form)
- Affects twice as many women than men (typically in their 20's and 30's)
- Characterized by clearly defined relapses (exacerbations) during which new
symptoms appear and old one worsen or reappear
- Relapse can last days or months; it is followed by periods of remissions during
which client as either a partial or total recovery
Multiple Sclerosis
*Four Main types*
Type 2 - ANSWER 2. Secondary-Progressive